Kenikir leaves (Cosmos caudatus. Kunth) contain various secondary metabolic compounds, quercetin which has the potential as an immunomodulator. This study aims to determine number of leukocytes, lymphocytes, neutrophils, monocytes, CD4 T cells, ODF ethanol extract film of kenikir leaves in Wistar rat strain and macroscopic and histopathalogic images of spleen organs. The research used Spektrofo…