Diarrheal disease caused by Escherichia coli bacteria is still common in Indonesia. Kersen plant (Muntingia calabura L.) is widely used to treat various diseases, namely jaundice, gout and cough, but it can also be used as an antipyretic, antioxidant, anti-inflammatory, antidiabetic, antibacterial and antiulcer. Kersen leaves contain active compounds of flavonoids and tannins which act as antib…