ABSTRACT THE CORRELATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) AND COGNITIVE FUNCTION IN ELDERLY PATIENTS AT THE GERIATRIC OUTPATIENT CLINIC OF RSMH PALEMBANG Devin Fidela, Yuniza, Nur Riviati, Iche A. Liberty Department of Internal Medicine, Faculty of Medicine, Sriwijaya University Dr. Mohammad Hoesin Hospital Palembang Background: Cognitive impairment represents a major public health c…
This study aims to determine the significant effect of the application of the Simulation Based Learning model on the learning activity of students at SMAN 2 Indralaya Utara. This study uses a quantitative approach with an experimental method. The population in this study were all students of class X of SMAN 2 Indralaya Utara with a total of 80 students. The sample in this study was class X.1 as…
Background: Aging is often accompanied by cognitive decline, where Mild Cognitive Impairment (MCI) serves as a transitional phase at risk of developing into dementia. The pathophysiology of this condition is closely related to neurobiological mechanisms, including low levels of Brain-Derived Neurotrophic Factor (BDNF) and the high prevalence of Vitamin D insufficiency in the elderly population.…
Rice is a major food commodity that serves as the economic backbone for the community in South Sumatra, including East Ogan Komering Ulu Regency. In an effort to improve harvest efficiency and reduce yield losses, the use of mechanization technology such as the combine harvester has been implemented as an alternative to conventional harvesting methods. A combine harvester is a machine that inte…
Optimization of the extraction process and testing of the antioxidant activity of Spirulina platensis microalgae extract is important for the development of natural microalgae-based antioxidant sources. Optimization was performed using multilevel factorial design 23 with 24 runs in Design Expert® 13 using three factors, namely solvent type (ethanol, acetone), temperature (25°C, 40°C), and ex…
Pelawan leaves (Tristaniopsis merguensis Griff.) are a plant that contain important secondary metabolites such as flavonoids, tannins, saponins, and phenolic compounds, which have potential roles in regulating lipid metabolism. This study aimed to evaluate the effect and effective dose of the ethanolic extract of pelawan leaves in reducing total cholesterol, Low Density Lipoprotein (LDL), and t…
This study aims to determine the effect of the application of the Experiential Learning model on students' learning motivation in the Pancasila Education subject at SMAN 2 Indralaya Utara. This study uses a quantitative approach with an experimental method. Data collection was carried out through documentation, observation, and questionnaire techniques. The study population included all 93 stud…
Oyster mushroom (Pleurotus ostreatus) is a type of horticulture that contains many important vitamins, economic potential and high nutritional content, making the cultivation of this commodity a promising business opportunity, not only from a financial aspect but also in skills development and community empowerment. This study aims to (1) describe the stages of the oyster mushroom cultivation p…
Hyperthyroidism is a chronic endocrine disorder requiring long-term treatment; therefore, medication adherence plays an important role in therapeutic success and quality of life improvement. Lack of education may lead to poor adherence and negatively affect patients’ condition. This study aimed to analyze the effect of educational intervention on medication adherence and quality of life among…
This study aims to examine the effect of financial distress, firm age, and the independent board of commissioners on audit delay. The study is grounded in agency theory and signaling theory. Secondary data were obtained from annual reports and financial statements of companies listed in the LQ45 index on the Indonesia Stock Exchange during 2021-2024. The population consists of all LQ45 companie…
The learning process in high school requires students to actively communicate in class discussions; however, in reality, not all students have an adequate level of communication self-efficacy. Differences in learning experiences outside of school, such as participation in English courses, are suspected to also influence students' confidence in communicating. This study aims to determine whether…
Tuberkulosis sensitif obat (TB SO) masih menjadi permasalahan kesehatan masyarakat di Indonesia, termasuk di Provinsi Bengkulu. Pada tahun 2022–2024 masih terdapat kesenjangan antara estimasi dan temuan kasus TB. Data menunjukkan bahwa pada tahun 2024 estimasi kasus TB di Provinsi Bengkulu sebesar 7.772 kasus, sedangkan kasus yang ditemukan sebanyak 3.624 kasus. Penelitian ini bertujuan untuk…
Civil Law
Akreditasi klinik merupakan instrumen penting dalam upaya peningkatan mutu pelayanan kesehatan serta menjadi kewajiban bagi seluruh FKTP sesuai Permenkes Nomor 34 Tahun 2022. Namun, hingga tahun 2025, capaian akreditasi klinik swasta di Kota Palembang menunjukkan bahwa 44,2% klinik swasta masih belum terakreditasi. Penelitian ini bertujuan untuk menganalisis determinan yang berhubungan dengan p…
Mental health problems among university students have become an increasingly important issue, while access to mental health services remains suboptimal. On the other hand, telemedicine serves as an alternative solution for mental health services that is more accessible and flexible. This study aimed to analyze the factors influencing the utilization of telemedicine-based mental health services …
The implementation of digital health services in primary healthcare requires both organizational readiness and health workers’ acceptance as system users. This study analyzes the readiness and perceptions of health workers toward digital health services at Tanjung Batu Public Health Center, Ogan Ilir Regency. A qualitative study with a phenomenological approach was conducted through in depth …
Osteoarthritis is a progressive degenerative disease that causes chronic pain, dysfunction, and disability so that it has the potential to reduce the quality of life. The intensity of pain and the level of anxiety are thought to be related to the patient's quality of life. This study aimed to analyze the relationship between pain intensity and anxiety levels and quality of life in osteoarthriti…
The development of digital technology has transformed various aspects of social life, including the tradition of sharing Eid al-Fitr allowances (THR). One such transformation is reflected in the use of the DANA Kaget feature within the DANA digital wallet application, which is widely used by Generation Z. This study aims to examine the role of social connectedness needs and entertainment needs …
Child sexual harassment has significant psychological, physical, and social consequences. Insufficient knowledge among children regarding sexual harassment constitutes one of the contributing factors to its occurrence; therefore, preventive educational interventions are essential. This study aimed to examine the effect of PUKESDES game-based media on elementary school students' knowledge of sex…