Skripsi

PENGARUH PEMBERIAN VITAMIN D TERHADAP PERUBAHAN KADAR PLASMA HOMA-IR, ADIPONEKTIN, HOMOSISTEIN, DAN Hs-CRP SEBAGAI BIOMARKER SINDROM METABOLIK DAN ATEROSKLEROSIS PADA PENDERITA EPILEPSI YANG MENDAPAT OBAT ANTIBANGKITAN ENZIMATIK

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Introduction: Epilepsy is a manifestation of brain disorders that is associated with high morbidity. Decreased vitamin D levels and incidence of metabolic syndrome in patients receiving antiseizure medications (ASMs) have been reported. This study aimed to analyse the effect of vitamin D administration on changes in plasma levels of HOMA-IR, adiponectin, homocysteine, and hs-CRP as biomarkers of metabolic syndrome and atherosclerosis in epilepsy patients receiving enzymatic AEDs. Methods: This study encompassed a double-blind placebo-controlled randomised controlled trial (RCT) design. The intervention was vitamin D dose of 2,000 IU per day for 12 weeks. Measurements of vitamin D, HOMA-IR, adiponectin, hs-CRP, and homocysteine levels were conducted before and after the intervention and differences in levels were considered significantly different when statistical tests showed p

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Availability

Detail Information

Series Title

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Call Number

T1789172025

Publisher

Indralaya : Prodi Magister Ilmu Biomedik, Fakultas Kedokteran Universitas Sriwijaya., 2025

Collation

xiii, 104 hlm.; ilus.; tab.; 29 cm.

Language

Indonesia

ISBN/ISSN

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Classification

610.280 7

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Ilmu Biomedik

Specific Detail Info

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Statement of Responsibility

MI

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