Skripsi
PROFIL KLINIS DAN LUARAN PERDARAHAN INTRAKRANIAL NONTRAUMATIK PADA BAYI DI PEDIATRIC INTENSIVE CARE UNIT RSUP DR. MOHAMMAD HOESIN
Background. Nontraumatic intracranial hemorrhage is bleeding within the cranial cavity without a history of head trauma. The most common cause in infants is vitamin K1 deficiency (VKDB), while other contributing factors include vascular malformations, infections, tumors, cardiac abnormalities, systemic conditions, or idiopathic causes. This hemorrhage can result in brain injury and increased intracranial pressure, often requiring care in the Pediatric Intensive Care Unit (PICU) and contributing to morbidity and mortality in infants. Methods. This descriptive observational study with a retrospective approach used medical record data of infants aged >28 days to 6 months diagnosed with intracranial hemorrhage due to vitamin K1 deficiency at Dr. Mohammad Hoesin General Hospital Palembang from January 1, 2023, to May 30, 2025. Variables included sociodemographic, birth and perinatal characteristics, clinical signs and symptoms, laboratory findings, types of hemorrhage, surgical intervention, and clinical outcomes. Results. Of the 42 patients included, all were aged 1–3 months (100%), predominantly male (61.9%), and resided outside Palembang (83.3%). Most were born at term (84.2%) through spontaneous vaginal delivery (90.9%) assisted by midwives (75%). A total of 54.3% of patients did not receive prophylactic vitamin K1. The majority of patients had severe consciousness impairment (GCS 1 lesion) (38.1%) and subdural hematoma (SDH) (26.2%). Most patients underwent surgery (54.8%). Clinically, 27 patients (64.3%) survived. Conclusion. All patients with nontraumatic intracranial hemorrhage were 1–3 months old, mostly male, and primarily from outside Palembang. Most were born via spontaneous vaginal delivery assisted by midwives and had not received prophylactic vitamin K1. The majority presented with severe conditions, especially impaired consciousness and seizures, often with coagulation disorders, combination-type bleeding, and underwent surgery. Most survived, while the rest died. Keywords. Nontraumatic Intracranial Hemorrhage, Vitamin K1 Deficiency Bleeding (VKDB), infants, Pediatric Intensive Care Unit (PICU).