Skripsi

HUBUNGAN KADAR ALBUMIN DAN GLOBULIN SERUM DENGAN TINGKAT KEPARAHAN TB PARU DI RSMH PALEMBANG

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Background. Pulmonary tuberculosis (TB) is a chronic infectious disease that remains a major health concern in Indonesia. Its prolonged inflammatory process can affect serum protein levels, particularly albumin and globulin. Based on current theoretical evidence, albumin functions as a negative acute-phase protein that decreases during inflammation and malnutrition, whereas globulin increases as a humoral immune response to Mycobacterium tuberculosis infection. This study aimed to determine the association between serum albumin and globulin levels and the radiological severity of pulmonary TB. Methods. This analytical observational study employed a cross-sectional design using secondary medical record data of adult pulmonary TB patients at Dr. Mohammad Hoesin General Hospital Palembang. Collected data included demographic characteristics, serum albumin level, serum globulin level, A/G ratio, and TB severity categorized as mild, moderate, or severe based on chest X-ray findings. Bivariate analysis was performed using the chi-square test. Results. The findings showed that most patients had normal albumin and globulin levels, with the majority of cases classified as mild TB severity. Chi-square analysis revealed a significant association (p

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Detail Information

Series Title

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Call Number

T1883642025

Publisher

Palembang : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya., 2025

Collation

xvii, 132 hlm.; ilus.; tab, 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

616.995 07

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

tuberkulosis
Prodi Pendidikan Dokter

Specific Detail Info

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Statement of Responsibility

MI

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