Skripsi

KORELASI KADAR HbA1c DENGAN KADAR PROFIL LIPID PADA PASIEN DIABETES MELITUS

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Background : Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia resulting from impaired insulin secretion or reduced insulin sensitivity. Hemoglobin A1c (HbA1c) reflects long-term glycemic control and is suspected to be associated with changes in lipid profiles. This study aimed to analyze the correlation between HbA1c levels and lipid profile parameters in patients with diabetes mellitus. Methods : This descriptive study employed a case series design and involved 113 patients with diabetes mellitus enrolled in the Prolanis program at Dempo and Merdeka Primary Health Centers in Palembang City. Data were obtained from medical records, including HbA1c, total cholesterol, HDL, LDL, triglycerides, and patient characteristics. Data analysis was performed using SPSS, consisting of the Kolmogorov–Smirnov normality test, comparative tests (Independent t-test, Mann–Whitney, One-Way ANOVA, Kruskal–Wallis), and Spearman correlation analysis. Results : The majority of patients were aged ≥60 years (57.5%), female (72.6%), had normal body mass index (32.7%), had been diagnosed with DM for ≥3 years (74.3%), and were receiving monotherapy (58.4%). HbA1c levels indicated poor glycemic control. The lipid profile showed elevated total cholesterol, LDL, and triglycerides, along with decreased HDL in most patients. There were significant differences in HbA1c levels based on sex and type of DM therapy (p0.05). However, a significant correlation was observed between HbA1c and triglyceride levels (p≤0.05). Conclusion : A significant correlation was found between HbA1c levels with triglycerides, whereas no significant correlation was observed with HDL, LDL, and total cholesterol among patients with diabetes mellitus. Keywords: Diabetes melitus, HbA1c, Lipid profile.

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Detail Information

Series Title

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Call Number

T1883582025

Publisher

Palembang : Prodi Pendidikan Dokter, Fakultas Kedokteran Universitas Sriwijaya., 2025

Collation

xxi, 122 hlm.; ilus.; tab, 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

616.462 07

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Diabetes Melitus
Prodi Pendidikan Dokter

Specific Detail Info

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Statement of Responsibility

MI

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