Skripsi

UJI AKTIVITAS ANTIBAKTERI HIDROLISAT KOLAGEN TULANG IKAN TENGGIRI (SCOMBEROMORUS SP.) TERHADAP BAKTERI STREPTOCOCCUS MUTANS

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Background: Streptococcus mutans is one of the main factors causing dental caries. The side effects of improper use of antibacterial drugs create an urgency to seek alternative materials. Mackerel fish is a type of marine fish whose collagen hydrolysate has potential as an alternative antibacterial agent. Aim: This study aims to determine the antibacterial activity of collagen hydrolysate from mackerel fish bones against Streptococcus mutans. Methods: This research is an in vitro laboratory study. Collagen was extracted with an acid solution, then hydrolyzed using bromelain enzyme with different hydrolysis times of 60 minutes, 90 minutes, and 120 minutes. The antibacterial activity against Streptococcus mutans was tested using the Kirby-Bauer disk diffusion method to determine the diameter of the inhibition zone. The positive control in this study was 0.2% chlorhexidine. Results: The highest average diameter of the inhibition zone was shown by the positive control group with 0.2% chlorhexidine, measuring 21.15 mm (p>0,05), followed by the groups with hydrolysis times of 120 minutes (p0,05), and 60 minutes (p

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Detail Information

Series Title

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Call Number

T1517502024

Publisher

Indralaya : Prodi Kedokteran Gigi dan Mulut, Fakultas Kedokteran Universitas Sriwijaya., 2024

Collation

ix, 74 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

615.329 07

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

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Subject(s)

Prodi Kedokteran Gigi dan Mulut

Specific Detail Info

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Statement of Responsibility

KA

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