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AKURASI D-DIMER SEBAGAI PREDIKTOR KEMATIAN PASIEN COVID-19 DI RSUD SITI FATIMAH PROVINSI SUMATERA SELATAN
Background: The COVID-19 pandemic, which has spread worldwide and resulted in fatalities, has had a significant impact. Globally, as of March 7, 2023, there have been 759,408,703 confirmed cases of COVID-19, including 6,866,434 deaths, reported to the WHO. Indonesia ranked first in the highest number of COVID-19 cases in ASEAN in 2021, with a total of 4,253,598 cases. According to the Indonesia Health Profile for 2021, the COVID-19 Case Fatality Rate (CFR) in Indonesia was 3.4%, with South Sumatra being the fifth-ranked province. The increase in D-dimer levels and poor laboratory test results serve as markers of worsening patient condition, which is also supported by age and comorbidities. The objective of this study was to determine the accuracy of D-dimer as a predictor of mortality in COVID-19 patients at RSUD Siti Fatimah. Method: This study employed a retrospective cohort design using secondary data from COVID-19 patients with medical records treated at RSUD Siti Fatimah, South Sumatra Province, from January to December 2021. The sampling technique involved total sampling, comprising 928 patients. Results: The majority of patients (83.94%) survived, and 59.16% had D-dimer levels below 500 ng/mL. The average D-dimer levels were higher in patients who died compared to those who survived (p-value
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