Skripsi
KARAKTERISTIK KLINIKOPATOLOGI MORBUS HANSEN DI BAGIAN/KSM PATOLOGI ANATOMI RS KEMENKES MOHAMMAD HOESIN PALEMBANG PERIODE 2020-2024
Background: Morbus Hansen (MH), also known as leprosy, is a chronic infectious disease caused by Mycobacterium leprae that primarily affects the skin and peripheral nerves. Despite global elimination efforts, MH remains a public health problem in Indonesia. Histopathological examination plays an essential role in establishing the diagnosis and determining the disease spectrum. This study aimed to describe the clinicopathological characteristics of Morbus Hansen patients at the Department/KSM of Anatomical Pathology, RS Kemenkes Mohammad Hoesin Palembang, during the period 2020–2024. Methods: This study was a descriptive observational study with a cross-sectional design. Data were obtained from medical records and histopathological reports of Morbus Hansen patients examined at the Department/KSM of Anatomical Pathology, RS Kemenkes Mohammad Hoesin Palembang, from January 1, 2020 to December 31, 2024. Total sampling was applied. Data were analyzed descriptively and presented as frequency distributions. Results: The results showed that 56 Morbus Hansen patients met the inclusion criteria. The highest prevalence was found in 2024 (0.1%). The most affected age group was 31–40 years (25%). Female patients were more predominant than males (55.4% vs 44.6%). The most common lesion location was the upper and lower extremities (62.5%). Based on histopathological classification, the most frequently identified type was Borderline Lepromatous (41.1%), followed by Borderline Tuberculoid (26.8%). Conclusion: In conclusion, Morbus Hansen cases at RS Kemenkes Mohammad Hoesin Palembang during 2020–2024 were predominantly found in the productive age group, more common in females, with lesions mainly located on the extremities, and the most frequent histopathological type was Borderline Lepromatous. These findings are expected to contribute to improved diagnosis and management of Morbus Hansen based on local data. Keywords: Morbus Hansen, leprosy, clinicopathological characteristics, histopathology, anatomical pathology