Skripsi

DESAIN SCAFFOLD TULANG AUXETIC DENGAN RASIO POISSON NEGATIF BERBASIS FSI UNTUK OPTIMASI KINERJA BIOMEKANIK DAN NUTRIEN

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Design and development of auxetic bone scaffold with a Negative Poisson’s Ratio (NPR) have become a strategic approach to improving both mechanical performance and nutrient transport in bone tissue engineering applications. Re-entrant Hexagonal Honeycomb (RHH), Double Arrowhead (DAH), and Auxetic Star Shape (ASS) bone scaffold were successfully developed using with Polycaprolactone (PCL) as the base material and simulated using a Fluid–Structure Interaction (FSI) computational approach. Geometrical parameters and material properties of the auxetic scaffold models were obtained from the literature and from human cancellous bone morphology related to porosity. The results show that each scaffold model exhibits a strong relationship with its Poisson’s ratio value, where increasingly negative Poisson’s ratio corresponds to higher Von Mises Stress, wall shear stress (WSS), fluid pressure, and nutrient flux. Interestingly, the permeability of the three bone scaffold models demonstrates a unique pattern in which longitudinal permeability decreases while transverse permeability increases as the negative Poisson’s ratio intensifies. The findings indicate that all three auxetic scaffold models meet the criteria of an ideal bone scaffold, superior biomechanical performance, with fluid and nutrient transport still within the physiological range capable of stimulating human osteoblast activity.

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Detail Information

Series Title

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Call Number

T1896032025

Publisher

Indralaya : Prodi Teknik Mesin, Fakultas Teknik Universitas Sriwijaya., 2025

Collation

xxvii, 130 hlm.; ilus.; tab.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

612.760 7

Content Type

Text

Media Type

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Carrier Type

-

Edition

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Subject(s)

Prodi Teknik Mesin
Gerakan Tubuh--Biomekanika

Specific Detail Info

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Statement of Responsibility

MI

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