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EVALUASI RASIONALITAS TERAPI PASIEN DEMAM TIFOID DI INSTALASI RAWAT INAP RSI SITI KHADIJAH PALEMBANG
Typhoid fever is a common infectious disease in Indonesia and may lead to serious complications if not managed appropriately. This study aimed to evaluate the rationality of drug therapy in hospitalized typhoid fever patients based on eight parameters of appropriateness. This research employed a prospective descriptive analytical design. Data were obtained from patients’ medical records and direct assessment of inpatients at RSI Siti Khadijah Palembang during the October–November 2025 period. The evaluation of therapeutic rationality demonstrated that appropriateness of diagnosis (100%), indication (100%), patient (100%), drug selection (100%), antibiotic, antipyretic, and antiemetic dosage (100%), and route of administration (100%) were fully achieved. The duration of antipyretic and antiemetic therapy was appropriate in 100% of cases, while the appropriateness of antibiotic duration was 80.43%. Monitoring for adverse effects was observed in 97.8% of antipyretic use and 100% of antiemetic use. Bivariate analysis examining the relationship between the rational use of antipyretics and body temperature outcomes showed a statistically significant association (p-value = 0.044; p < 0.05). In conclusion, the rationality of therapy among typhoid fever patients at RSI Siti Khadijah met the established criteria for rational use of medicines, with ceftriaxone being the most frequently prescribed antibiotic. Keywords: Antibiotics, Rationality, Symptomatic Therapy, Typhoid Fever
| Title | Edition | Language |
|---|---|---|
| EVALUASI RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN GERIATRI DI INSTALASI RAWAT INAP RS ISLAM SITI KHADIJAH KOTA PALEMBANG | id |