Skripsi

UJI AKTIVITAS ANTIULCER EKSTRAK ETANOL KULIT BATANG TANAMAN SUKUN (Artocarpus Altilis) PADA TIKUS YANG DIINDUKSI TUKAK DENGAN ETANOL ABSOLUT

---

Breadfruit bark (Artocarpus altilis) is a medicinal plant containing important secondary metabolites such as flavonoids, phenolics, saponins, and triterpenoids. These compounds are thought to play a role in protecting the gastric mucosa. This study aims to evaluate the antiulcer activity of ethanol extract of breadfruit bark through biochemical parameters, macroscopic, and microscopic analysis in male Wistar rats induced by absolute ethanol. A total of 36 rats were divided into six treatment groups: normal group (Na-CMC 0.5%), negative control (Na-CMC 0.5%), positive control (Omeprazole 20 mg/kgBW), and three extract groups at doses of 100 mg/kgBW, 200 mg/kgBW, and 400 mg/kgBW. The extract was administered for 14 days, then the rats were induced with absolute ethanol on the 15th day to induce gastric ulcers except for normal controls. The results showed that breadfruit bark extract had a significant protective effect on the gastric mucosa (p0.05). These findings indicate that breadfruit bark extract has the potential as a candidate for alternative natural-based therapy for the treatment of gastric ulcers.

---

Availability

Detail Information

Series Title

-

Call Number

T1921892026

Publisher

Indralaya : Prodi Ilmu Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2026

Collation

xx, 104 hlm.; ilus.; 29 cm

Language

Indonesia

ISBN/ISSN

-

Classification

615.321 07

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

-

Subject(s)

Prodi Ilmu Farmasi
Gastrointestinal - Efek Obat

Specific Detail Info

-

Statement of Responsibility

KA

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment