Skripsi
HUBUNGAN KADAR FERITIN SERUM DAN KADAR KALSIUM SERUM MATERNAL TERHADAP KEJADIAN PREEKLAMSIA DI RSUP DR. MOHAMMAD HOESIN PALEMBANG
Introduction: Preeclampsia remains a major cause of maternal morbidity and mortality in Indonesia. Its pathogenesis involves endothelial dysfunction, oxidative stress, and systemic inflammation. Ferritin, as an iron storage protein, plays a role in the inflammatory process, while low calcium levels can cause vasoconstriction and increased blood pressure through activation of the renin-angiotensin-aldosterone system. The relationship between maternal serum ferritin and calcium levels and preeclampsia requires further investigation. Objective: To determine the relationship between maternal serum ferritin and calcium levels and the incidence of preeclampsia at Dr. Mohammad Hoesin General Hospital in Palembang. Methods: This study was an analytical observational study with a cross-sectional design conducted at the Obstetrics Inpatient and Outpatient Units of Dr. Mohammad Hoesin General Hospital in Palembang from September 2024 to September 2025. The study subjects were pregnant women with and without preeclampsia who met the inclusion criteria. Ferritin and calcium levels were measured from maternal serum samples and analyzed using the Chi-square test and logistic regression. Results: The mean serum ferritin level in the preeclampsia group was higher than in the non- preeclampsia group, while the serum calcium level was significantly lower (p
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