Skripsi

UJI AKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN LABU SIAM (Sechium Edule (Jacq.) Swartz) DAN HISTOPATOLOGI PANKREAS PADA TIKUS PUTIH WISTAR JANTAN KONDISI HIPERGLIKEMIK

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Chayote leaves (Sechium edule (Jacq.) Swartz) contain secondary metabolites like flavonoids, tannins, and saponins acting as antidiabetic agents through beta-cell protection. This study aimed to determine the antidiabetic activity of the ethanolic extract of chayote leaves (EECL) and evaluate its effect on pancreatic histopathology in hyperglycemic male Wistar rats. Hyperglycemia was successfully induced using a high-fat and high-fructose diet (HFFD) for thirty days. Maceration using 96% ethanol produced a yield of 13.98%. Twenty-four rats were divided into six distinct groups: normal, negative control (0.5% Na-CMC), positive control (Metformin 45 mg/kg BW), and three EECL dosage groups (100, 200, and 400 mg/kg BW). The research results showed that EECL administration at all three doses significantly (p

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Availability

Detail Information

Series Title

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Call Number

T1936702026

Publisher

Indralaya : Prodi Ilmu Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sriwijaya., 2026

Collation

xx, 16 hlm.; ilus.; tab.; 29 cm

Language

Indonesia

ISBN/ISSN

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Classification

616.462 07

Content Type

Text

Media Type

unmediated

Carrier Type

-

Edition

-

Subject(s)

Diabetes Mellitus
Prodi Ilmu Farmasi

Specific Detail Info

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Statement of Responsibility

KA

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