Image of POTENSI EKSTRAK ETANOL SEMUT RANGRANG (Oecophylla smaragdina F.) SEBAGAI ANTIHIPERGLIKEMIK PADA MENCIT (Mus musculus) GALUR SWISS WEBSTER DAN SUMBANGANNYA PADA PEMBELAJARAN BIOLOGI SMA
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POTENSI EKSTRAK ETANOL SEMUT RANGRANG (Oecophylla smaragdina F.) SEBAGAI ANTIHIPERGLIKEMIK PADA MENCIT (Mus musculus) GALUR SWISS WEBSTER DAN SUMBANGANNYA PADA PEMBELAJARAN BIOLOGI SMA

Hyperglycemia is a clinical condition reflecting an imbalance in glucose metabolism within the body, which may be managed through the utilization of animal-derived compounds, one of which is the weaver ant (Oecophylla smaragdina F.). This study aimed to determine the efficacy of various doses of weaver ant ethanol extract in reducing blood glucose levels in Swiss Webster strain mice (Mus musculus). The study employed an experimental method with a Completely Randomized Design (CRD) consisting of five treatment groups and five replications. The test animals were male mice weighing 20–30 grams, which were first induced with alloxan at a dose of 40 mg/kgBW intravenously for 72 hours until a hyperglycemic state was achieved. The parameter measured was blood glucose level following induction and extract administration on Days-3, 0, 3, 7, and 14. Data were analyzed using SPSS version 30 through normality testing, homogeneity testing, One-Way ANOVA, and the Duncan Multiple Range Test (DMRT). The results demonstrated that administration of weaver ant ethanol extract had a highly significant effect on reducing blood glucose levels in alloxan-induced mice (p < 0.01). The most effective dose was observed in treatment group P3 at 90 mg/kg body weight, which reduced blood glucose levels from 219.8 ± 9.6 mg/dL to 93.6 ± 7.6 mg/dL by day 14, approaching a normoglycemic state. These findings suggest that weaver ant ethanol extract holds potential for development as a natural antihyperglycemic agent and may serve as a foundation for further research.

Availability
#
Central Library (Reference) T2003922026
T200392
Available but not for loan - Not for Loan
Detail Information
Series Title
-
Call Number
T2003922026
Publisher
Indralaya : Prodi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan Universitas Sriwijaya.,
Collation
xiii, 145 hlm.; ilus.; tab.; 29 cm.
Language
Indonesia
ISBN/ISSN
-
Classification
615.320 7
Content Type
Text
Media Type
-
Carrier Type
-
Edition
-
Subject(s)
Prodi Pendidikan Biologi
Ekstrak Etanol Semut Rangrang
Specific Detail Info
-
Statement of Responsibility
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