Skripsi
ANALISIS RASIONALITAS TERAPI PASIEN ANAK DENGAN DIARE AKUT DI RSI SITI KHADIJAH PALEMBANG Putra, Muhammad Az
Acute diarrhea remains a leading cause of pediatric morbidity in Indonesia, necessitating appropriate management to prevent dehydration and serious complications. This study evaluates the therapeutic patterns and the rationality of drug use in pediatric patients with acute diarrhea based on eight appropriateness parameters. Conducted as a prospective study, data were obtained from medical records and inpatient assessments at RSI Siti Khadijah Palembang during the period of October–November 2025. Results from 50 patients indicated that antibiotic therapy was dominated by Ceftriaxone (68%) and Ampicillin-Sulbactam (32%), with 100% adherence to Zinc supplementation. The evaluation of therapeutic rationality revealed 100% compliance for right diagnosis, right indication, right patient, right drug, right route of administration, right duration of therapy, and side-effect monitoring. However, the parameter for right dosage achieved a score of 94%, with three cases identified as being below the therapeutic range (underdose). In conclusion, the therapeutic rationality for pediatric acute diarrhea patients at RSI Siti Khadijah generally aligns with rational drug use criteria, characterized by the predominant use of Ceftriaxone and full adherence to supportive Zinc therapy.
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