Background: Acrochordon is a benign fibroepithelial skin tumor commonly found in intertriginous areas and thought to be associated with insulin resistance (IR). Hyperinsulinemia resulting from IR contributes to fibroblast and keratinocyte proliferation through activation of the insulin-like growth factor-1 signaling pathway. The homeostatic model assessment of insulin resistance (HOMA-IR) is a …
Deteksi karies gigi masih menjadi tantangan karena bergantung pada interpretasi visual subjektif, yang dapat menyebabkan inkonsistensi. Metode deep learning, khususnya Convoulutional Neural Network (CNN), telah menunjukkan potensi besar dalam meningkatkan akurasi diagnostik berbasis radiografi. Tujuan: Untuk meninjau literatur terkini mengenai aplikasi deep learning dalam deteksi karies gigi ot…
Background: Acute Kidney Injury (AKI), the most serious complications in critically ill patients admitted to the Intensive Care Unit (ICU). Under these conditions, the required renal replacement therapy modality that can be performed in the ICU is Continuous Renal Replacement Therapy (CRRT). However, the mortality rate remains high in patient with CRRT. This study aims to analyze the relationsh…
Background: An excessive inflammatory response and dysregulation of the immune system in severe sepsis may progress to septic shock and increase mortality. Vitamin D plays an important role in immune modulation. This study aimed to analyze the association between vitamin D levels and sepsis severity and to determine the cut-off point of vitamin D associated with the risk of septic shock in ICU …
Background: Postoperative pain in laparotomy patients poses a significant clinical challenge due to extensive tissue trauma and systemic inflammatory response. Non-opioid multimodal analgesia has become the primary strategy to optimize pain control while minimizing opioid use. A direct comparison between paracetamol–ketorolac and paracetamol–ketamine combinations for postoperative pain mana…
Latar Belakang: Anemia pada anak masih menjadi masalah kesehatan dengan prevalensi yang cukup tinggi dan dapat mengganggu pertumbuhan serta kemampuan belajar anak. Kurangnya pengetahuan orang tua mengenai anemia menjadi salah satu faktor yang memengaruhi pencegahan dan penanganan anemia pada anak. Tujuan: Mendeskripsikan asuhan keperawatan anak dengan edukasi media video untuk meningkatkan peng…
Background: Streptococcus mutans is a Gram-positive bacterium that plays an important role in the formation of dental caries through its ability to form biofilms and produce organic acids. Various materials are used in dental caries treatment because they possess antibacterial effects. Robusta coffee bean extract (Coffea canephora) is known to contain bioactive compounds such as flavonoids, chl…
The advancement of medical imaging technology has produced increasingly complex data that require fast and accurate analysis. However, the interpretation of medical images still requires considerable time, relies heavily on medical professionals, and is prone to interpretation errors. Therefore, this study aims to develop an Image Captioning system capable of automatically generating descriptio…
Pendahuluan : Tekanan intraokular (TIO) memainkan peran penting dalam diagnosis dan manajemen beberapa penyakit mata, terutama yang terkait dengan peningkatan tekanan intraokular. Tingginya TIO dan Central Corneal Thickness (CCT) merupakan faktor risiko hilangnya penglihatan. Hingga saat ini Goldmann Applanation Tonometry (GAT) masih menjadi gold standard pengukuran TIO dan telah terdapat beber…
Background: Docetaxel is a chemotherapy drug used to inhibit cell cleavage in nasopharyngeal cancer. Canalicular and ductal stenosis is a common side effect of weekly docetaxel therapy, which often causes epiphora. This study aimed to analyze the correlation between the duration of docetaxel chemotherapy and lacrimal punctum stenosis in patients with nasopharyngeal cancer. Methods: This descrip…
Background: : Centella asiatica has long been used as a wound-healing agent due to its triterpenoid content, which possesses anti-inflammatory, antioxidant, and antifibrotic properties . During the wound healing process, TGF- β regulates re-epithelialization, inflammation, angiogenesis, and granulation tissue formation. Centella asiatica has been shown to decrease TGF-β 1, and contribute to t…
Background: Corneal incisions alter the curvature of the corneal surface, leading to surgically induced astigmatism (SIA). Temporal incisions are generally superior to superior incisions due to improved surgical access and lower SIA values. This study aims to analyze the survival of SIA values resulting from temporal corneal incisions in cataract patients undergoing phacoemulsification. Methods…
ABSTRACT Background: Lumbar spinal stenosis is a degenerative condition characterized by narrowing of the spinal canal, leading to pain and neurological deficits. Inflammatory processes are thought to play a key role in its pathogenesis, with increased levels of inflammatory mediators such as C-Reactive Protein (CRP) and Interleukin-1β (IL-1β). However, the correlation between these biomarker…
Background: The first thousand days of life is a period from the beginning of pregnancy until two years of age. Dental caries is a microbiological disease of the hard dental tissues caused by the interaction of bacteria that produce acids through carbohydrate fermentation, resulting in demineralization of inorganic substances and destruction of the organic structure of the teeth. Objective: Thi…
Introduction:Breast carcinoma is the most common breast malignancy among women in Indonesia,accounting for 30.8% of female cancer cases in 2020, with high prevalence at Dr. Mohammad Hoesin General Hospital (20.9% in 2019–2020). Serum calcium plays a crucial role in cellular regulation of cancer through homeostasis of PTH, vitamin D, and mechanisms such as PTHrP and local osteolysis, where hyp…
Latar belakang: Fraktur pelvis merupakan cidera pada struktur cincin pelvis, yang dapat melibatkan tulang ilium, ischium, pubis, sakrum, atau kombinasi dari beberapa bagian tersebut. Penelitian ini bertujuan untuk mengetahui hubungan faktor-faktor risiko pasien fraktur pelvis dengan mortalitas. Metode: Desain penelitian deskriptif dalam bentuk serial kasus. Seluruh kasus fraktur pelvis di RSUP …
This dissertation is motivated by the disharmony between accelerated economic development and the preservation of environmental functions in Indonesia. The current Environmental Protection and Management (PPLH) legal system is considered to be dominated by a rigid anthropocentric and positivistic paradigm, often failing to capture the moral values and wisdom living within society. This study ai…
Law No. 16 of 2025 on the Fourth Amendment to Law No. 19 of 2003 recognizes Alternative Dispute Resolution (ADR) through deliberation and mediation, with agreements that are final and binding for the parties in dispute. However, this regulation only applies to disputes between state-owned enterprises (SOEs), while disputes between SOEs and Private-Owned Enterprises (POEs) are not regulated for …
Background: Lung cancer is a malignant tumor originating from lung tissue, including the respiratory epithelium. It is one of the leading causes of cancer-related mortality worldwide and is frequently diagnosed at an advanced stage with a poor prognosis. Systemic inflammation and nutritional status play important roles in disease progression and patient survival. The modified Glasgow Prognostic…
Background The prognosis of advanced-stage lung cancer remains poor despite ongoing therapeutic advances. Systemic inflammation and nutritional status are increasingly recognized as important prognostic determinants. The Advanced Lung Cancer Inflammation Index (ALI) is a prognostic parameter that evaluates the degree of systemic inflammation by combining body mass index (BMI), serum albumin lev…
Background: Dental caries was one of the most common chronic diseases among schoolaged children, with prevalence rates of 84.8% in children aged 5–9 years and 63.8% in those aged 10–14 years based on the 2023 Indonesian Health Survey. High consumption of added sugar and low levels of knowledge regarding its impact on oral health were identified as contributing factors. This condition highli…
Background: Parental knowledge plays an important role in maintainingoral health of children with physical disabilities who have motor limitations anddepend on parents for dental care. Objective: To analyze the relationship betweenparents’ level of knowledge and dental caries in children with physical disabilitiesat SLB D YPAC Palembang City. Methods: A descriptive-analytical quantitativestud…
Background: Dental anxiety is a primary barrier in pediatric dental care that causes treatment refusal and poor oral health. The Tell-Play-Do (TPD) method using a smartphone dentist game is a modification of conventional behavior management that potentially reduces anxiety through interactive education and distraction. Objective: This study aims to determine the effect of the TPD behavior manag…
Background: Oral health in visually impaired children required special attention because visual limitations could affect their ability to maintain oral hygiene independently, increasing the risk of plaque accumulation and oral diseases. The selection of toothbrush type and proper brushing technique were important factors in controlling plaque in these manual and sonic electric toothbrushes in v…
Latar belakang: Coronary Artery Bypass Graft (CABG) adalah prosedur bedah jantung yang dapat memengaruhi hasil pascaoperasi, termasuk lama perawatan di ICU Kardiovaskular (CV ICU). Durasi CPB dan waktu klem aorta (AoX) yang berkepanjangan diduga berhubungan dengan peningkatan morbiditas serta perpanjangan masa perawatan pascaoperasi. Tujuan: Menentukan hubungan antara lama CPB dan waktu AoX den…
Background Hemorrhagic stroke is a neurological condition with high mortality, particularly in patients requiring mechanical ventilation due to decreased consciousness or respiratory failure. Initial neurological severity, comorbidities, and complications during hospitalization may influence patient outcomes. This study aimed to analyze factors associated with mortality in hemorrhagic stroke pa…
Background: Vascular Cognitive Impairment (VCI) represents a leading cause of post-stroke cognitive impairment in Asia, including Indonesia, with substantial implications for quality of life and economic burden. Current management strategies emphasize early detection through the identification of specific biomarkers as predictive factors. The LDL/ApoB ratio is considered a more accurate surroga…
Background: Stroke is a catastrophic disease with a significant economic burden, particularly for neurointervention procedures such as mechanical thrombectomy and coiling. A disparity exists between standard costs and actual billing charges for these procedures at Dr. Mohammad Hoesin Hospital Palembang. This study aimed to analyze the factors influencing hospitalization costs of stroke patients…
Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, predominantly presenting with sensory symptoms such as numbness and tingling. Conservative therapy with oral mecobalamin is widely used; however, the onset of improvement is often slow. Perineural injection of mecobalamin may provide a faster local effect, but clinical evidence remains limited. This study aimed t…