STUDI IN SILICO POTENSI SENYAWA PADA DAUN SIRIH (Piper betle L.) SEBAGAI AGEN…

Hyperlipidemia is characterized by increased normal levels of plasma lipids such as cholesterol, triglycerides, cholesterol esters, phospholipids, and sometimes plasma lipoproteins, including very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL), along with decreased high-density lipoproteins (HDL). This study used an in silico approach to predict the molecular potential of be…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN ALPUKAT (PERSEA AMERICANA), DAUN JAMBU…

Long-term exposure to excess free radicals in the body can cause oxidative stress and various diseases, so antioxidant compounds are needed to neutralize free radicals. This research was conducted to determine the strongest antioxidant activity of avocado leaves, water guava leaves and cherry leaves which have been used empirically by the Ogan Ilir community. The extract with the strongest anti…

DOMESTIKASI BUAH MERAH

Edition

-

ISBN/ISSN

978-602-440-864-0

Collation

82 hlm. : ill. ; 23 cm.

Series Title

-

Call Number

634.6 Dar d

OPTIMASI FORMULA NANOSTRUCTURED LIPID CARRIER EKSTRAK KULIT JERUK MANIS (Citr…

The utilization of sweet orange peel is still minimal as it is often overlooked after fruit processing for consumption, despite being rich in bioactive compounds, including flavonoids, especially for topical preparations. Previous research has mainly focused on conventional formulations with limitations in skin penetration. The Nanostructured Lipid Carrier (NLC) delivery system can enhance perc…

AKTIVITAS ANTIOKSIDAN SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT DAUN…

Excessive free radicals in the body can cause oxidative stress conditions which result in tissue damage. This condition can be prevented by consuming antioxidants. Cherry leaves (Muntigia calabura L.) often used as a medicinal plant and are believed to have antioxidant properties. Based on previous research, methanol extract of cherry leaves has strong antioxidant activity, while the ethyl acet…

PEMISAHAN FRAKSI KOLOM DARI FRAKSI ETIL ASETAT DAUN KERSEN (MUNTINGIA CALABUR…

Kersen leaves (Muntingia calabura L.) have been proven to have antioxidant properties, both in the form of crude extracts and fractions. The ethyl acetate fraction of kersen leaves separated by vacuum liquid column chromatography has strong antioxidant activity (IC50 43,40 µg/mL). This research is a continuation of the previous research by further separating the fraction of vacuum liquid colum…

EVALUASI AKTIVITAS ANTIOKSIDAN DAN ANTIINFLAMASI FRAKSI DAUN SUKUN (Artocarpu…

Plants that contain high levels of flavonoid and phenol compounds have the potential to act as antioxidants and anti-inflammatories. One of them is the breadfruit plant (Artocarpus altilis). This study aims to determine the antioxidant and anti-inflammatory activity of breadfruit leaf fractions. The research began with extraction by maceration using solvents with varying polarities (n-hexane, e…

EFEKTIVITAS EKSTRAK BINAHONG (ANREDERA CORDIFOLIA) TERHADAP ZONA HAMBAT BAKTE…

Background: Staphylococcus aureus is a gram-positive bacterium that causes skin diseases, pneumonia, respiratory tract infections, nosocomial bacteremia and is resistant to antibiotics. The incidence of antibiotic-resistant Staphylococcus aureus is increasing. Binahong is a herbal plant that has many benefits, one of which is as an antibacterial. Methods: This study used an experimental design.…

EFEKTIVITAS PEMBERIAN LIDOKAIN 3,5 mg/KgBB 20ml INTRAPERITONEAL TERHADAP NYER…

Background: Post-cesarean section pain is a clinical challenge commonly encountered in medical practice. Despite various approaches to postoperative pain management, achieving optimal pain control remains challenging. One therapy being explored is intraperitoneal lidocaine administration. Lidocaine is known to have potential analgesic effects and may give the operator a benefit in reducing post…

PEMISAHAN SENYAWA METABOLIT DARI FRAKSI n-HEKSANA KAYU BATANG MURBEI PUTIH (M…

Separation of metabolite compounds from the n-hexane fraction of the wood of the M. alba L. plant has not been widely carried out. TLC analysis showed that M. alba L. has many metabolite compounds. This research was aimed to determine metabolite compounds from the n-hexane fraction of the wood of the M. alba L. plant using the gas chromatography-mass spectrometry (GC-MS) method. The extraction …

SOLASI SENYAWA METABOLIT SEKUNDER TURUNAN FENOLIK DARI FRAKSI ETIL ASETAT BAT…

Morus alba L. is a plant from Moraceae family which is found in tropical and subtropical areas. M. alba plant was reported to have displayed several bioactivities such as antioxidant, antitumor, antibacterial, anticancer, antidiabetic, and anti-inflammatory. M. alba plant has a diversity of secondary metabolites. This research was aimed to isolate and identify secondary metabolite compounds fro…

UJI POTENSI IMUNOMODULATOR PADA MENCIT (MUS MUSCULUS) DAN ANTI PROLIFERASI SA…

Sungkai (Peronema canescens Jack.) is one of woody plants which is usually found in the Southern part of Sumatra which is often used as an herbal plant by people for flu and fever. This research was aimed to know immunomodulator potency of Sungkai in mice (Mus muculus) and effect extract to proliferation of Saccharomyces cerevisiae yeast and leukocytes. Yeast proliferation is associated with in…

Atlas Tumbuhan Obat Indonesia Jilid II

Edition

-

ISBN/ISSN

979-661-065-5

Collation

xii, 214 hal. : ilus. ; 24 cm

Series Title

-

Call Number

633.88 Dal a

RASIONALITAS PENGGUNAAN RANITIDINE PADA KASUS GASTRITIS DI PUSKESMAS SEKIP PA…

Gastritis is a disease caused by inflammation of the gastric mucosa characterized by pain, swelling, and irritation of the gastric mucous membrane. One of the Pharmacological therapy for managing gastritis involves H2 receptor antagonists, Ranitidine. For treating gastritis, a 150-300mg dose is administered once or twice a day. Rational drug use involves administering medication according to th…

PENGARUH EKSTRAK ETANOL DAUN ALPUKAT (PERSEA AMERICANA MILL.) TERHADAP PERTUM…

Staphylococcus aureus is one of the most commonly exposed bacteria and causes infection in humans. Efforts that can be made in medicine are using antibiotics. The use of antibiotics has recently been irrational and has led to antibiotic resistance. Efforts that can be made to prevent resistance are using alternative medicine. Alternative medicine that can be used is plants. Avocado leaves are h…

PENGARUH EKSTRAK ETANOL DAUN ALPUKAT (PERSEA AMERICANA MILL.) TERHADAP PERTUM…

Background. Shigellosis is a clinical condition caused by invasion of Shigella species in the epithelium lining the terminal ileum, colon and rectum. Efforts that can be made to treat shigellosis are using fluoroquinolone antibiotics. However, cases of resistance of patients infected by Shigella to fluoroquinolone antibiotics have been reported to have increased in the Southeast Asian. This stu…

HUBUNGAN KEPATUHAN KONSUMSI DAN JENIS KELASI BESI DENGAN KADAR FERRITIN SERUM…

Background: Thalassemia is a hereditary hemolytic disease that is an autosomal recessive, characterized by a disorder in hemoglobin synthesis. The management of thalassemia, particularly major thalassemia, includes regular blood transfusions and iron chelation therapy to control iron accumulation. The iron level in the body can be determined through a common examination, which is the serum ferr…

TAKSONOMI TUMBUHAN OBAT-OBATAN

Edition

1

ISBN/ISSN

979-420-300-9

Collation

ix., 457 hlm.; ill.; 21 cm

Series Title

-

Call Number

581.634 Tji t

AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 80 DAN…

Bitter leaf extract (Andrographis paniculate (Burm.f) Wall. Ex Ness) contains secondary metabolites andrographolide and quercetin which have potential antibacterial activity. This research aims to determine the nanoemulsion formulation with a combination of Tween 80 and Ethanol 96% concentration on the activity of Propionibacterium acnes and the stability of ICH Q1A (R2). Data analysis in this …

AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 20 DAN…

Sambiloto leaves (Andrographis paniculate (Burm. F) Wall ex. Ness) contain andrografolid and flavonoids as the main compounds that have potential as antibacterial. Nanoemulsion with a combination of tween 20 and PEG-400 was carried out to produce preparations that have better antibacterial effects and are thermodynamically stable. This study was conducted to determine the characteristics and st…

STUDI IN SILICO POTENSI SENYAWA DAUN OREGANO (Origanum vulgare L.) SEBAGAI AG…

Tuberculosis is a contagious respiratory tract infection caused by Mycobacterium tuberculosis. This research utilized an in silico approach to predict the molecular potential of target compounds in oregano leaves (Origanum vulgare L.) for antituberculosis activity. The potential compounds in oregano leaves included phytol, carvacrol, γ-terpinene, p-cymene, and cyclotetradecane. The SwissADME d…

KORELASI RASIO NEUTROFIL LIMFOSIT DAN RASIO PLATELET LIMFOSIT DENGAN SKOR GRA…

Latar Belakang: Sindrom koroner akut (SKA) merupakan kelompok penyakit yang meliputi angina tidak stabil, NSTEMI dan STEMI, serta merupakan salah satu diagnosis yang sering ditemukan pada ruang IGD. Troponin T umumnya digunakan untuk diagnosis, serta skor grace sebagai prognosis pasien SKA. Sayangnya pemeriksaan tersebut tidak bisa dilakukan kepada semua orang karena pemeriksaan tersebut belum …

OPTIMASI KONSENTRASI TWEEN 80 DAN ETANOL 96% DALAM SEDIAAN NANOEMULSI EKSTRAK…

Ekstrak daun sukun (Artocarpus altilis (Parkinson) Fosberg) mengandung senyawa metabolit sekunder utama flavonoid dan fenolik. Penelitian ini bertujuan untuk mengetahui optimum konsentrasi Tween 80 dan Etanol 96% dalam sediaan nanoemulsi ekstrak etanol daun sukun. Optimasi dilakukan dengan desain faktorial 22 menggunakan Design Expert 12®. Formula optimum yang diperoleh selanjutnya dilakukan k…

STUDI STABILITAS PROTRANSETOSOM KLINDAMISIN HCL DENGAN LIOPROTEKTAN TREHALOSA…

Clindamycin HCl as a topical anti-acne drug has low bioavailability due to its hydrophilic nature which is difficult to penetrate the stratum corneum. Propionibacterium acnes, the main pathogen of acne, lives in the sebaceous glands in the dermis, so it requires deeper penetration. Transethosomes can increase penetration because they are classified as lipid nanovesicles with good elasticity and…

OPTIMASI PATCH TRANSDERMAL EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) TER…

Wounds or damage to part of the body tissue if not treated immediately will cause infection and even death. Plants that can help the wound healing process include alpha mangostin compounds from mangosteen skin (Garcinia mangostana L.). Optimization of active substance delivery is carried out in the form of transdermal patch preparations. This study aims to obtain the optimum formula for transde…

EVALUASI PENGGUNAAN OBAT PADA PASIEN DISPEPSIA RAWAT JALAN DI RSUD SITI FATIM…

Dyspepsia is a condition of discomfort that persists (episodic) or experiences recurrence of pain in the upper abdomen, nausea, vomiting, bloating, fullness, fullness of the stomach, and pain in the epigastrium. with an incidence proportion of 35.5% in Palembang City in 2015. Rational use of dyspepsia medication is very important to ensure that the medication given is appropriate, safe, and eff…

PREPARASI DAN KARAKTERISASI TRANSDERMAL PATCH EKSTRAK KULIT MANGGIS (Garcinia…

Mangosteen peel extract has an alfa-mangosteen compound that can accelerate cell healing by stimulating fibroblast growth, thus providing effects as an anti�inflammatory and antimicrobial. The choice of transdermal patch dosage form for mangosteen peel extract aims to effectively deliver active substances through the skin to reach the systemic. The purpose of this study was to obtain a formul…

OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI ETOSOM FRAKSI ETIL ASETAT EKSTRAK DAUN…

Daun singkong (Manihot Esculenta Crantz.) mengandung senyawa metabolit yang dihasilkan salah satunya flavonoid terdapat rutin dikenal sebagai quercetin-3-rutinoside yang berpotensi sebagai anti acne. Etosom memiliki kemampuan sebagai pengantar untuk meningkatkan transfer bahan aktif melalui kulit dengan lebih efisien dalam hal permeabilitas kulit. Tujuan dari penelitian ini adalah mengetahui fo…

UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia Tuber…

The Purple golden leaves (Ruellia tuberosa L.) contain secondary metabolites in the form of flavonoid compounds which have antioxidant activity which can act as a hepatoprotector. This study aims to determine the hepatoprotective activity of ethanol extract of purple golden leaves (Ruellia tuberosa L.) in male Wistar white rats induced by CCl4 based on parameters measuring SGOT, SGPT and ALP le…

UJI EFEKTIVITAS EKSTRAK DAUN SUNGKAI (Peronema canescens Jack) SEBAGAI BIOINS…

The grasshopper has a tendency to eat plant leaves, causing physical damage such as tears in the leaves, and can even cause the loss of all leaves. One way to deal with the presence of locusts is by using sungkai leaf bioinsecticide (Peronema canescens) which contains poison for locusts. The purpose of this study was to determine the effect of sungkai leaf extract and the optimal concentration …