Obesity is a chronic metabolic condition characterized by excessive fat accumulation and low-grade systemic inflammation, which play crucial roles in the pathogenesis of insulin resistance and various metabolic complications. Intermittent fasting, particularly the time-restricted feeding (TRF) type, has been shown to improve metabolic homeostasis and reduce inflammation; however, evidence regar…
Low back pain (LBP) is a major cause of disability with a high prevalence, including 18% in Indonesia. Most cases are nonspecific, reducing productivity and requiring pharmacological as well as rehabilitation management. Patient satisfaction is an essential indicator of service quality and can be assessed using the MRPS questionnaire. Previous studies reported that patient satisfaction has not …
Introduction: Flies are mechanical vectors of enteric pathogens and may carry Soil-Transmitted Helminth (STH) eggs, particularly in open-dumping landfill environments. This study assessed STH egg contamination on flies at the Palemraya disposal site and described fly density, species composition, and local environmental conditions. Methods: A descriptive cross-sectional study was conducted in t…
Background: Childhood obesity has become a serious public health challenge that requires the identification of contributing factors, as pharmacological therapies are often less effective. This study aims to analyze the association between sociodemographic and behavioral factors (emotional eating, snacking habits, and family mealtime practices) and obesity among elementary school students, as we…
Background: Endometriosis is a chronic gynecological disorder characterized by the growth of endometrial tissue outside the uterine cavity, often leading to chronic pelvic pain and infertility. This condition negatively affects the quality of life and reproductive health of women of reproductive age. The paucity of data on the prevalence and associated risk factors across populations highlight …
Background. Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity, which may cause chronic pelvic pain and infertility. This condition often leads to a reduction in ovarian reserve due to inflammatory processes, fibrosis, and follicular damage. One of the indicators used to assess ovarian reserve is the Anti-Müllerian Hor…
Background: Iron deficiency is a common complication in hemodialysis patients and has been known to have a negative impact on cognitive function. This study aimed to analyze the association of iron deficiency with cognitive impairment in chronic hemodialysis patients. Methods: This observational study was conducted using cross-sectional design in chronic hemodialysis patients at Mohammad Hoesin…
Cytomegalovirus Retinitis (CMVR) is an opportunistic ocular infection caused by CMV and commonly occurs in patients with Human Immunodeficiency Virus (HIV), particularly in the advanced stage of Acquired Immune Deficiency Syndrome (AIDS), where it serves as a major cause of visual impairment and blindness with a relatively high prevalence in developing countries. The absence of comprehensive da…
Spinal anesthesia for lower extremity surgery often causes complications such as back pain. Body mass index (BMI) is suspected to influence the risk of back pain, but studies on this relationship are still limited, especially at RS Mohammad Hoesin Palembang. This was a quantitative observational analytic study with a cross-sectional design. The sample consisted of postoperative lower extremity …
Chronic rhinosinusitis (CRS) is a clinical syndrome characterized by symptomatic inflammation of the nasal cavity and paranasal sinus mucosa lasting for more than 12 weeks. CRS is classified into two types, primary and secondary CRS. Primary CRS refers to a persistent inflammation without an identifiable etiopathogenic factor, while secondary CRS develops as part of another pathological process…
Reference values are essential basis for clinical decision making dan can vary between populations. Until now, in Palembang, specifically at RSUP dr. Mohammad Hoesin Palembang, there are currently no established reference values for the TG/HDL-C ratio, non-HDL-C, and remnant-C. Therefore, research establish these reference values is necessary. This study is an observational analytical research …
In the current digital era, technological dependence and escalated screen time are widespread phenomena, particularly among medical students. This occurrence is influenced by variables such as self-control and level of loneliness. However, the relationship among these variables has not been investigated among medical students at Sriwijaya University. Therefore, this study aims to investigate th…
Conjunctivitis is the most common eye inflammation disease worldwide and is frequently encountered in primary healthcare facilities, including community health centers. Conjunctivitis can occur in individuals of all ages and genders. Although often considered a mild condition, conjunctivitis can lead to serious complications if not managed properly; therefore, appropriate treatment according to…
Systemic Lupus Erythematosus (LES) is a condition in which autoantibodies against body cells occur that can affect various organ systems. Globally, the most common manifestations in LES patients are hematologic and renal manifestations. The level of disease activity in LES patients can be measured by the MEX-SLEDAI index. Some previous studies have suggested a correlation between hematologic an…
Pseudomonas aeruginosa is an opportunistic gram-negative bacterial pathogen frequently associated with nosocomial infections. The challenge of antibiotic resistance has driven interest in alternative treatments, such as plant extracts. Purple sweet potato (Ipomoea batatas L.) is known to contain bioactive secondary metabolites with potential antibacterial properties. This in vitro experimental …
Introduction: Complementary feeding (CF) refers to food provided to children aged 6–24 months to meet their nutritional needs when breast milk alone is insufficient. Studies indicate that many mothers of children aged 6–12 months do not provide CF appropriately. Knowledge and attitudes of the mother significantly influence the accuracy of CF practices for children in this age group. To enha…
Background. Cervical cancer is a malignancy of the cervical epithelium primarily caused by infection with the Human Papillomavirus (HPV). In 2022, GLOBOCAN reported 36,964 new cases and 20,708 deaths due to cervical cancer. Hematological inflammatory parameters can reflect systemic inflammation that correlates with cancer severity. This study aimed to analyze the association between hematologic…
Background: Dry eye disease (DED) is a multifactorial disorder of the ocular surface characterized by the loss of tear film homeostasis. The prevalence of DED in Indonesia reaches 27.5%, with the evaporative type being the most common. Prolonged use of digital devices significantly contributes to the development of DED. Radiation emitted from digital screens is more easily absorbed by younger t…
Background. Urinary tract infection (UTI) is a common health problem among females and is strongly influenced by genital hygiene. Lack of knowledge and poor personal hygiene practices, especially among adolescent girls, can increase the risk of developing UTIs. Therefore, this study aimed to determine the relationship between the level of knowledge of genital hygiene and UTI prevention behavior…
Background: Cardiomegaly refers to an abnormal enlargement of the heart, which can be detected through various diagnostic methods, with echocardiography regarded as the gold standard. However, in patients who are bedridden, along with the limitations in healthcare infrastructure at some medical facilities, antero-posterior (AP) chest radiography serves as a more accessible alternative. This stu…
Medical students often face heavy academic burdens, high expectations for achievement, and difficulties in balancing studies with personal life. These conditions make them vulnerable to experiencing emotional mental disorders. However, awareness and intention to seek psychological help remain low. Seeking psychological help is an active effort to obtain support or treatment related to mental he…
Background: According to data released by the World Health Organization (WHO) in 2022, around 450,000 cases of TB-RO will occur throughout the world. In TB-RO patients there was an increase in the number of neutrophils and a decrease in the number of leukocytes. RNL calculations are carried out as an indicator that plays a role in reflecting the body's inflammatory response to infection. At the…
Background: Breast Milk is an essential source of nutrition for infants, containing micronutrients, macronutrients, and bioactive components that support their health and development. Breast milk consists of 87%-88% water, 7% lactose, 1% protein, and 3.8% fat, as well as various vitamins and antibodies that play a role in protecting infants from diseases. The composition of breast milk is influ…
Background: Hepatoma, or hepatocellular carcinoma, is the primary liver tumor accounting for 90% of liver tumor cases. In certain cases, hepatoma patients only undergo laboratory examinations without radiological imaging. An alternative method is needed to monitor tumor progression, predict patient prognosis, and determine appropriate treatment without radiological examinations, namely by measu…
Background: The most common superficial fungal skin disease, which has become a global health problem, is Tinea versicolor or Pityriasis versicolor. Personal hygiene behaviors were performed to maintain personal cleanliness and health. Several behaviors increased the risk of Pityriasis versicolor among scavengers, including not showering immediately after work, rarely changing work clothes, and…
Menopause is the cessation of menstruation for 12 consecutive months due to the loss of ovarian follicle function. Various factors can influence the menopausal process, such as dietary patterns, sleep patterns, stress levels, and physical activity. A study conducted by Mirrah in Palembang in 2023 revealed that 93.93% of women experienced menopausal symptoms. However, research on the relationshi…
Bakteri Klebsiella penumoniae dapat menyebabkan infeksi serius, terutama ketika sudah menyebar pada organ tubuh. Penggunaan antibiotik sering menjadi pilihan dalam menangani infeksi, namun bakteri dapat beradaptasi dengan membentuk biofilm. Senyawa antibiofilm yang biasa digunakan berbahan sintetik kimia yang dapat berdapak negatif pada manusia. Oleh karena itu, pencarian alternatif antibiofilm…
Background. Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, requiring rational pharmacological therapy. Metformin is the first-line therapy for type 2 DM as recommended by WHO and the National Formulary. Defined Daily Dose (DDD) measurement enables a quantitative evaluation of drug use. However, studies on DDD for metformin in South Sumatra remain limited.…
Cervical cancer is the main cause of cancer death among woman and the third most cancer case in the world. High expression of VEGF in cervical cancer is linked to a poor prognosis, therefore anti-VEGF therapy has an important role in cervical cancer resolution. Several studies show that emodin inhibit proliferation, migration, and a formation of endothelial cells stimulated by VEGF. This resear…
Infectious diseases are a major health problem in Indonesia, with antibiotics being the primary choice for treatment. However, inappropriate antibiotic use can lead to resistance, increasing morbidity, mortality, and healthcare costs. The World Health Organization (WHO) recommends the Defined Daily Dose (DDD) method to standardize and measure antibiotic use for effective monitoring. This study …