Background. Dacryocystitis is an inflammation of the lacrimal sac, commonly caused by tear stagnation due to obstruction of the nasolacrimal duct. Based on its clinical presentation, dacryocystitis is classified into acute and chronic forms. If not properly managed, particularly in the acute phase, dacryocystitis may lead to several complications that can affect visual function. Research on dac…
Background: Porphyromonas gingivalis was one of the Gram-negative anaerobic bacteria that played an important role in the pathogenesis of periodontal disease. The increasing resistance of bacteria to synthetic antibiotics encouraged the search for alternative antibacterial agents from natural sources. Snakehead fish (Channa striata) was known to contain bioactive compounds such as albumin and m…
Background: Pneumonia is one of the leading causes of patients requiring intensive care unit (ICU) admission and contributes significantly to high morbidity and mortality rates. The length of ICU stay is influenced by various clinical factors, including age, comorbidities, and types of antibiotic therapy. Objective: To identify factors influencing the length of stay among pneumonia patients in …
Backgrounds: Head injury is one of the leading causes of morbidity and mortality in trauma cases and remains a major public health concern worldwide. In Indonesia, head injuries most commonly occur as a result of traffic accidents, particularly among productive age groups. Profiling head injury patients is essential for evaluating healthcare services, management strategies, and prevention progr…
Background: Hirschsprung disease (HSCR) is a congenital intestinal disorder caused by aganglionosis that requires histopathological confirmation; a full-thickness biopsy (FTB) is sometimes used to establish the diagnosis and determine definitive management. Methods: This retrospective descriptive-analytic study used medical records from Dr. Mohammad Hoesin General Hospital Palembang (January 20…
Backgrounds: Impetigo is a common superficial skin infection often caused by Streptococcus pyogenes. Mupirocin is a first-line treatment, but rising antibiotic resistance encourages the search for alternative therapies, including pineapple core (Ananas comosus L. Merr) extract, which contains active compounds such as bromelain with potential antibacterial effects. This study aimed to evaluate t…
Thalassemia is a genetic blood disorder that requires lifelong management, including regular blood transfusions and iron chelation therapy. This condition affects the quality of life of children, which is strongly influenced by their parents’ level of knowledge in providing care. This study aimed to determine the relationship between parents’ level of knowledge and the quality of life of ch…
Introduction: Sepsis is a life-threatening organ dysfunction, one of the leading cause of morbidity and mortality worldwide, including Indonesia. The rapid progression of the disease and its variable clinical manifestations affect sepsis- related mortality. Biomarker testing, particularly plasma lactate level, plays a vital role as an indicator of tissue hypoxia, a predictor of mortality, and a…
Background: Allergic rhinitis is one of the most common atopic diseases in children, characterized by inflammation of the nasal mucosa due to type I hypersensitivity reactions mediated by immunoglobulin E (IgE), often caused by house dust mites. Methods: This study is an observational analytical study with a cross-sectional approach using medical records and laboratory data on pediatric allergi…
Soil-Transmitted Helminth (STH) infections remain a public health problem in Indonesia, with a prevalence of 28.12%. STH infections can lead to growth retardation in children and decreased work productivity in adults. Transmission occurs through the fecal–oral route, and consumption of contaminated vegetables can serve as a medium for infection. The development of hydroponic farming systems, …
Breast cancer is the most common type of cancer in the world. Chemotherapy can be one of the treatment options and has been proven to have a significant impact on patient survival. However, there are concerns about the side effects of chemotherapy that can affect the cognitive function of patients, known as chemotherapy-induced cognitive impairment (CICI). This study aims to determine the cogni…
Chemotherapy is the main treatment for breast cancer; however, it may cause cognitive impairment, known as chemobrain, which is characterized by a decline in memory, attention, reasoning, concentration, processing speed, executive function, and visual ability. Clinicopathological factors such as age, education, marital status, cancer stage, type and number of chemotherapy cycles are believed to…
Coronary Slow-Flow Phenomenon (CSFP) is characterized by delayed coronary blood flow without significant stenosis, with a prevalence of 1–7% and 38.3% at Dr. Mohammad Hoesin General Hospital Palembang. The condition often causes recurrent chest pain and increases cardiovascular risk. Endothelial dysfunction is suspected to play a role in its pathogenesis, while dyslipidemia may contribute thr…
Cholelithiasis is the formation of gallstones due to an imbalance between cholesterol, bile salts, and phospholipids. Factors such as age, gender, and body mass index (BMI) play important roles in this process. Older age is associated with decreased activity of the enzyme 7α-hydroxylase, which reduces bile acid production, while higher estrogen levels in females increase cholesterol secretion …
Polycystic Ovary Syndrome (PCOS) is an endocrine disorder characterized by an imbalance of LH and FSH hormones, insulin resistance, and dyslipidemia, which increase the risk of metabolic complications. Purple sweet potato (Ipomoea batatas L. Poir) is known to contain anthocyanins and flavonoids with antioxidant properties that contribute to improving lipid profiles. This study aims to evaluate …
Acute coronary syndrome (ACS) is one of the leading causes of cardiovascular morbidity and mortality worldwide, including in Indonesia. This condition occurs due to the sudden obstruction of coronary blood flow caused by rupture or erosion of atherosclerotic plaques. Platelet activation plays a role in the process of atherothrombosis and the formation of coronary thrombi. Platelet indices such …
Background: Musculoskeletal pain is one of the most common occupational health problems experienced by healthcare workers, particularly dentists. In Indonesia, the prevalence of musculoskeletal disorders among dentists reaches 58.9%, indicating that this condition is a significant issue requiring proper attention. Various risk factors contribute to this condition, including working posture, str…
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Urinary tract infection (UTI) is one of the most common complications associated with diabetes mellitus. This study aims to determine whether there is an association between patient characteristics specifically sex, age, and body mass index (BMI), and the incidence of urinary tract infection (UTI) in patients with…
Background. DSD is a heterogeneous group of congenital conditions associated with variations in chromosomes, gonads, or anatomical sex. CAH is classified as a DSD that is usually diagnosed based on ambiguous genitalia in newborn girls or salt-wasting crises. Early diagnosis and treatment of CAH DSD patients is crucial. However, a major challenge is that research conducted primarily at the natio…
Background: Neck pain is one of the most common musculoskeletal complaints among adolescents, particularly those who spend extend periods sitting and maintaining non-ergonomic neck positions during academic activities. Neck position can be assessed using the Craniovertebral Angle (CVA), which biomechanically correlates with increased load on the cervical muscles. However, evidence regarding the…
Background: The spine is the central supporting structure of the body. Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional structural deformity of the spine that occurs in adolescents 10-17 years old which is characterized by lateral curvature in the frontal plane, thoracic lordosis in the sagittal plane, and rotation of the vertebrae in the transverse plane, with a Cobb angle reaching…
Background: Anemia in pregnancy is a common maternal health problem contributing to prematurity, morbidity, and maternal–infant mortality. Low hemoglobin leads to placental hypoxia, HPA-axis activation, and increased prostaglandins that trigger early uterine contractions. This study analyzed the association between anemia and prematurity at RSUP Dr. Mohammad Hoesin Palembang. Methods: This an…
Background: Candy is a processed food in the form of a solid and if consumed excessively it will reduce the salivary pH which is one of the factors causing caries. This decrease occurs due to the activity of acid-producing bacteria in the oral cavity. Preventing a decrease in salivary pH can be done by adding gambir and xylitol to candy. Gambir is a herbal ingredient containing catechins and ta…
Background: The liver is susceptible to damage due to exposure to free radicals, which trigger oxidative stress. This condition increases AST and ALT enzymes, which are markers of liver injury. This study used CCl₄-induced Wistar rats as a model of liver damage. Antioxidants are needed to prevent damage, and silymarin was used as a positive control. Purple sweet potato leaf extract contains f…
Background. Endometrial carcinoma is a gynecological malignancy originating from the endometrial lining of the uterus. It ranks as the sixth most common cancer among women worldwide, and its incidence is associated with excessive estrogen exposure to the endometrium. This study aims to describe the risk profile and therapeutic modalities of patients with endometrial carcinoma treated at RSUP Dr…
Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a wide spectrum of clinical manifestations, ranging from mild cutaneous abnormalities to severe organ dysfunction. Previous studies have shown a decrease in lymphocyte count, or lymphopenia, in SLE patients, which is often associated with disease activity. However, research on the relationship betwee…
Background: Hypospadias is the second most common congenital anomaly found in males after cryptorchidism, with urethrocutaneous fistula being the most frequent postoperative complication. The incidence rate of urethrocutaneous fistula is one of the indication of the success of hypospadias management. The age at surgery is suspected to play a role in determining the treatment outcome. However, r…
Komplikasi umum yang dapat terjadi selama kehamilan adalah hipertensi, termasuk preeklampsi, hipertensi gestasional, dan hipertensi kronis, yang mempengaruhi hingga 10% kehamilan. Hipertensi yang tidak ditangani dengan baik dapat menyebabkan berbagai masalah kesehatan serius bagi ibu dan janin, seperti penyakit arteri koroner, penyakit ginjal kronis, dan hambatan pertumbuhan janin. Komplikasi a…
Introduction: S. aureus is one of the most frequently found and detected microorganisms in odontogenic infections of oral and cerebral abscesses. The treatment of odontogenic infections can be treated using antibiotics, which can be replaced by honey. Tembesu bitter black honey is a natural material that can be used as an antibacterial because it has high osmolarity, low pH (3,2-4,5), low water…
Introduction: Chronic Kidney Disease (CKD) is a chronic kidney disease that causes the accumulation of fluids, electrolytes, and waste in the body, which affects sleep patterns. In nursing interventions, the use of sleep support in the form of Progressive Muscle Relaxation (PMR) is a technique performed by contracting and stretching muscles to provide relaxation effects and address sleep distur…