A poor lifestyle can lead to the accumulation of free radicals that trigger degenerative diseases. Natural antioxidant compounds are needed to reduce free radical molecules formed in the body. One source of natural antioxidants comes from the kuku elang plant (Oxyceros longiflorus (Lam.) T. Yamaz.). The research methods used are extraction, fractionation, antioxidant activity test of fractions …
The leaves of the kencana ungu (Ruellia tuberosa L.) contains flavonoid compounds potentially as diuretics. This study aims to determine the diuretic activity of ethanol extract of kencana ungu leaves. Diuretic activity testing was carried out on 6 groups of test animals including normal (aquades), negative (NaCMC), positive (Furosemide), and three groups of treatment doses of 100, 200 and 400 …
Cassava leaves contain rutin compounds which are flavonoid derivatives that have antibacterial properties. Transdermal patch preparation was chosen for the ethyl acetate fraction of cassava leaves because it can produce effective preparations to deliver active compounds through the skin to reach the systemic. This study aims to obtain the best formula with plasticizer concentration in transderm…
Fraksi etil asetat daun singkong mengandung senyawa rutin yang efektif menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini bertujuan mengetahui variasi konsentrasi kalsium klorida sebagai crosslinker terhadap transdermal patch yang dihasilkan dan mengetahui aktivitas antibakteri sediaan transdermal patch. Polimer yang digunakan pada penelitian ini adalah kitosan dan natrium alg…
Kanker payudara adalah kelainan pada payudara yang berupa tumor karena proliferasi sel. Penelitian ini bertujuan memprediksi potensi molekuler dari senyawa daun Clinacanthus nutans terhadap aktivitas antiproliferasi kanker payudara dengan pendekatan bioinformatika. Ekstrak yang memiliki senyawa potensi ditelaah interaksi molekulernya. Basis data pkCSM menampilkan profil ADMET tiap senyawa. Basi…
Setelah sukses dengan buku `atlas tumbuhan obat indonesia` jilid 1 dan 2, kini kami hadirkan jilid 3 untuk melengkapi pengetahuan anda tentang berbagai tumbuhan yang memiliki khasiat obat. selain dilengkapi foto yang menunjang, uraian yang detail dan jelas akan membuat Anda mudah memahami isi buku ini. Segera simak semua informasi penting yang terangkum dalam buku ini dan ciptkan keluarga, masy…
Setelah Bertahun- tahun mendewakan obat modern yang memang bereaksi cepat kini, orang kembali melirik obat alami. Selain karena kesadaran akan resiko efek samping juga karena krisis ekonomi yang tak terelakkan. Untuk itulah, kami hadirkan buku ini untuk anda.
Background: Hyperuricemia is describes a condition where serum uric acid levels increase above normal values. Hyperuricemia occurs due to increased production and excretion of uric acid in the kidneys. The first line of treatment for reducing uric acid levels is xanthine oxidase inhibitors, allupurinol and febuxostat. However, many people use traditional medicine derived from natural plants. On…
Background: Purple sweet potato (Ipomoea batatas L.) is some type of potatoes that commonly used as an alternative for rice. Eventhough purple sweet potato was known to had phytopharmacal potentials, there is still few scientific literatures about the using of purple sweet potato as a therapeutic choice for renal fibrosis. This study is aimed to measure the efficacy of purple sweet potato extra…
Staphylococcus aureus is one of the most common bacterial infections in humans and is the causative agent of many human infections including bacteremia and sepsis. The use of antibiotics is a way of management, but excessive use can increase resistance. This study aims to see the effectiveness of antibacterial growth of ethanol extract of Carica papaya L. flowers on the inhibition of S.aureus A…
This research constitutes an experimental analytic study conducted in vivo, employing two parameters. The investigation of total cholesterol levels was conducted using a pre-test and post-test design with a control group. Conversely, the study of hepatic histology utilized a post-test with a control group design. Thirty male mice were allocated into five groups: a negative control, an obesity c…
Background: Indonesia's biodiversity is one of the features of our country. There are many plants with various potentials and benefits, including for health. One plant that can be used as an alternative treatment is the cherry plant. The benefits of the cherry plant are due to the secondary metabolite compounds it contains which can inhibit xanthine oxidase enzyme. Mistletoe can have the same c…
Background: Gout arthritis is an inflammatory disease of the joints caused by the deposition of monosodium urate crystals in the joint area, especially the extremities. In pharmacological therapy, allopurinol is the first-line choice in the management of gout, especially asymptomatic, intercritical, and chronic hyperuricemia phases. In Indonesia, especially now there is no data discussed gout a…
Background: Patient adherence is the key to success in the treatment of endometriosis. Monitoring of drug side effects needs to be done in order to obtain appropriate treatment results. Patients need to know information about the presence of side effects of leuprolide acetate injection drugs. This study was conducted to determine the incidence of side effects of using leuprolide acetate injecti…
Background: Over-the-counter drug (OTC) is a medicine that can be purchased freely without a doctor's prescription. Students tend to need medicine that can be accessed quickly and efficiently. Thus, the majority of population who do self-medication is mostly students. Unfortunately, there are still many people who do self-medication without being given sufficient education, so knowledge, attitu…
Background. Kersen leaf extract has the effect of inhibiting the xanthine oxidase enzyme and cherry mistletoe leaves also have the same properties considering that they are hemiparasites with their host. This study aims to determine the effect of n-hexane extract from mistletoe cherry leaves on the xanthine oxidase enzyme. Method. This research is an in vitro experimental research. The samples …
Background: Urinary tract infection (UTI) is one of the etiologies of febrile neutropenia (FN) in pediatric malignancy, an oncology emergency. Empirical antibiotic prescribing according to guidelines, based on local bacterial and resistance patterns, should be initiated immediately. This study aims to determine the prevalence of UTI, the distribution of bacterial and antibiotic sensitivity patt…
Background: Esophageal varices is the most life-threatening complication of portal hypertension in hepatic cirrhosis patients. Around 80% of cirrhosis patients will eventually experience this complication. Non-invasive parameters are needed for early detection of the degree of esophageal varices so that patients with severe varices can be immediately referred for endoscopic examination. In addi…
Introduction: Obesity is characterized by the abnormal accumulation of fat within the body, resulting from an imbalance between the energy intake and expenditure. Obesity elevates the risk of various chronic diseases, necessitating efforts to prevent and treat this condition. Previous research has revealed that Moringa oleifera leaf extract contains polyphenolic compounds with advantageous prop…
Background: Preeclampsia is the state of pregnant women experiencing hypertension with a systolic blood pressure of 140 mmHg or diastolic blood pressure of 90 mmHg and proteinuria totaling ≥ 300 mg. Nifedipine can be given to pregnant women with preeclampsia. Antihypertensive drugs of the calcium channel blocker group, namely nifedipine, are one of the drugs that are often used because of the…