Background. Systemic Lupus Erythematosus (SLE) is a complex systemic autoimmune disease with diverse multisystem manifestations. The prevalence of lupus in Indonesia is estimated at 0.5%. Patient satisfaction with treatment reflects subjective perceptions of therapeutic effectiveness, convenience, and side effects, and is closely related to adherence and long-term treatment continuity. To date,…
Background. Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis, presenting as Pulmonary TB or Extrapulmonary TB. Alterations in serum protein levels, particularly albumin and globulin, have been associated with inflammatory processes and immune status in TB patients. However, findings across studies remain inconsistent, making it necessary to further examine …
Background: Ptosis is a condition characterized by drooping of the upper eyelid resulting from dysfunction of the muscles, nerves, aponeurosis, or supporting structures of the eyelid. It may be congenital or acquired and can affect visual function as well as cosmetic appearance. Data regarding the characteristics and clinical features of ptosis in Palembang remain limited; therefore, this study…
Adolescents are a group with a high prevalence of mobile device use in Indonesia. Unwise use of mobile devices, either prolonged duration or inappropriate timing, may worsen sleep quality. Sleep quality refers to an individual’s level of satisfaction with their sleep experience, and poor sleep quality can negatively affect adolescents’ health. This study aimed to analyze the relationship be…
Background: Type 2 diabetes mellitus (T2DM) is a chronic disease with an increasing prevalence and remains a major cause of morbidity and mortality due to metabolic and vascular complications. These conditions require sustained glycemic control, one of which is supported through the Chronic Disease Management Program (PROLANIS) by BPJS Kesehatan. However, its implementation across primary healt…
Background Adolescent reproductive development between the ages of 10 and 19 requires special attention to reproductive health and the use of contraception to prevent unwanted pregnancies and sexually transmitted infections. Although modern contraceptive methods have proven effective, sociocultural barriers and lack of education hinder access and understanding among adolescents. Data indicate v…
Background. Dysmenorrhea or menstrual pain is a common gynecological problem among late adolescents and is often influenced not only by physiological factors but also by psychological conditions such as stress, anxiety, and depression. Medical students are particularly vulnerable to psychological disturbances due to high academic demands. This study aimed to determine the association between st…
Maternal Mortality Rate (MMR) is an important indicator for assessing a country’s health status and has become a global concern in efforts to achieve the SDGs 3.1 target. Although the national MMR in Indonesia shows a downward trend, the figure remains above the SDGs target. In South Sumatra Province, the MMR has fluctuated in recent years, with the highest number of cases recorded in Palemba…
Head injuries with moderate to severe severity accompanied by intracranial lesions remain a major clinical challenge, especially because they often lead to significant neurological impairment and even death. This study aims to describe the prognosis of patients with moderate to severe head injury based on lesion type, injury severity, time to arrival, time to surgery, the presence of sequelae, …
Background. Child sexual abuse is a serious issue with long-term physical, psychological, and social consequences. This study aimed to describe the injury patterns among child victims of sexual violence at Bhayangkara Hospital Palembang in 2024. The literature review was based on forensic medicine theories and the guidelines of Visum et Repertum (VeR) as a medico-legal document. Methods. This w…
Background. Pulmonary tuberculosis (TB) is a chronic infectious disease that remains a major health concern in Indonesia. Its prolonged inflammatory process can affect serum protein levels, particularly albumin and globulin. Based on current theoretical evidence, albumin functions as a negative acute-phase protein that decreases during inflammation and malnutrition, whereas globulin increases a…
Background: Stunting remains a nutritional problem among children under five in Indonesia. National data in 2024 reported a prevalence of 19.8%, indicating that the condition has not been fully resolved. Maternal knowledge about stunting plays an essential role in its prevention by shaping awareness, attitudes, and behaviors related to maintaining children’s health and nutritional needs for o…
Background. Laryngopharyngeal reflux (LPR) is a condition in which gastric contents reflux into the larynx and pharynx, resulting in symptoms such as globus sensation, chronic cough, dysphagia, and voice changes. These symptoms can substantially impair patients’ quality of life. This study aims to describe the quality of life of patients with LPR using the Laryngopharyngeal Reflux–Health-Re…
Background. Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by inflammation and multi-organ involvement. Its management requires a long-term multidisciplinary approach, which poses challenges for patients to maintain medication adherence. Poor adherence often leads to inadequate disease control, as reflected by higher disease activity, and worsened prognosis. T…
Background: Leukemia is a hematologic malignancy arising from the abnormal proliferation of immature leukocytes. It ranks as the 13th most frequently diagnosed cancer and the 10th leading cause of cancer-related death worldwide. Based on proliferation rate and cell lineage, leukemia is classified as acute or chronic, and as myeloid or lymphoid. Laboratory examination, cytomorphologic and cytoch…
Background. Osteosarcoma is the most common primary malignant bone tumor, particularly occurring in children, adolescents, and young adults. One of the genes that plays an important role in the pathogenesis of osteosarcoma is TP53, a tumor suppressor gene that regulates the cell cycle and apoptosis. Mutation or disruption of the expression of this gene causes loss of the ability to inhibit abno…
Background: Syphilis is a sexually transmitted infection caused by Treponema pallidum with an increasing trend in both global and national cases. This study is important to determine the incidence rate and the relationship between demographic profiles and risky sexual behavior in syphilis patients at the Dermatology, Venereology, and Aesthetics (DVE) Polyclinic of Mohammad Hoesin Hospital Palem…
Background. Thyroid heart disease (THD) is a cardiovascular disorder arising from thyroid dysfunctionhyperthyroidism or hypothyroidismwhich may cause palpitations and arrhythmias associated with systolic or diastolic dysfunction. This may progress to complication such as heart failure and increased mortality. Epidemiological data in Indonesia remains limited. Therefore, this study aimed t…
Background. Acute appendicitis is the most common cause of emergency abdominal surgery, yet its diagnosis remains difficult due to nonspecific early symptoms, leading to a 15–20% misdiagnosis rate. Although the Alvarado score is widely used and generally reliable, its accuracy varies across populations, potentially affecting surgical decisions. This study aimed to assess the relationship betw…
Background: Preterm birth is one of the leading causes of neonatal morbidity and mortality. The proportion of preterm births at Dr. Mohammad Hoesin General Hospital, Palembang, is relatively high, highlighting the need to identify maternal risk factors associated with preterm delivery in order to guide prevention strategies. Methods: This was an analytic observational study with a case–contro…
Background: Deaf children generally rely more on nonverbal communication, such as sign language, to interact. Sign language plays an important role in enhancing communication skills and social integration, thus it needs to be taught from an early age. The role play method offers a more interactive and participatory approach, allowing children to learn through direct experience and improve their…
Background: Adolescents are at risk of experiencing hormonal disturbances due to imbalanced nutritional status, in which excessive body mass index (BMI) may increase androgen levels and insulin resistance, while low BMI may reduce estrogen levels, thereby affecting menstrual cycle regularity and increasing sebum production that triggers acne vulgaris. This study aims to determine the relationsh…
Pendahuluan: Talasemia beta mayor merupakan kelainan genetik yang ditandai dengan gangguan pembentukan rantai β-globin sehingga menyebabkan anemia berat yang memerlukan transfusi darah rutin seumur hidup. Transfusi darah berulang dapat menimbulkan kelebihan zat besi (iron overload) yang ditandai dengan meningkatnya kadar ferritin serum. Peningkatan kadar ferritin yang tidak terkontrol dapat me…
Background: Cervical cancer is a malignancy highly influenced by Human Papillomavirus (HPV) infection, especially types 16 and 18. In Indonesia, cervical cancer cases and mortality remain high, while HPV vaccination coverage as a primary prevention effort is still suboptimal, particularly because parental decisions strongly affect child immunization. Lack of adequate knowledge and attitudes tow…
Background. Prostate cancer and benign prostatic hyperplasia (BPH) are the most common prostate disorders in elderly men, often presenting with similar clinical manifestations. Measurement of Prostate-Specific Antigen (PSA) levels plays an important role in the early detection of prostate abnormalities, although elevated PSA is not specific for malignancy. Due to limited local data on PSA level…
Background : Urinary Tract Infection (UTI) is one of the pregnancy risk factors caused by bacterial infection which, if not properly managed, can worsen pregnancy outcomes. Various risk factors such as age, socioeconomic status, education level, parity, frequency of sexual intercourse, number of pregnancies, history of UTI, and body mass index may influence the occurrence of UTI. This study aim…
Background. Coffee consumption is a common habit among medical students to improve concentration and cope with academic stress. Caffeine in coffee can affect sleep quality through adenosine receptor antagonism. This study aims to determine the relationship between coffee consumption patterns and sleep quality disturbances among medical students, Sriwijaya University, Class of 2022. Method. This…