Reference values are essential basis for clinical decision making dan can vary between populations. Until now, in Palembang, specifically at RSUP dr. Mohammad Hoesin Palembang, there are currently no established reference values for the TG/HDL-C ratio, non-HDL-C, and remnant-C. Therefore, research establish these reference values is necessary. This study is an observational analytical research …
In the current digital era, technological dependence and escalated screen time are widespread phenomena, particularly among medical students. This occurrence is influenced by variables such as self-control and level of loneliness. However, the relationship among these variables has not been investigated among medical students at Sriwijaya University. Therefore, this study aims to investigate th…
Conjunctivitis is the most common eye inflammation disease worldwide and is frequently encountered in primary healthcare facilities, including community health centers. Conjunctivitis can occur in individuals of all ages and genders. Although often considered a mild condition, conjunctivitis can lead to serious complications if not managed properly; therefore, appropriate treatment according to…
Systemic Lupus Erythematosus (LES) is a condition in which autoantibodies against body cells occur that can affect various organ systems. Globally, the most common manifestations in LES patients are hematologic and renal manifestations. The level of disease activity in LES patients can be measured by the MEX-SLEDAI index. Some previous studies have suggested a correlation between hematologic an…
Pseudomonas aeruginosa is an opportunistic gram-negative bacterial pathogen frequently associated with nosocomial infections. The challenge of antibiotic resistance has driven interest in alternative treatments, such as plant extracts. Purple sweet potato (Ipomoea batatas L.) is known to contain bioactive secondary metabolites with potential antibacterial properties. This in vitro experimental …
Introduction: Complementary feeding (CF) refers to food provided to children aged 6–24 months to meet their nutritional needs when breast milk alone is insufficient. Studies indicate that many mothers of children aged 6–12 months do not provide CF appropriately. Knowledge and attitudes of the mother significantly influence the accuracy of CF practices for children in this age group. To enha…
Background. Cervical cancer is a malignancy of the cervical epithelium primarily caused by infection with the Human Papillomavirus (HPV). In 2022, GLOBOCAN reported 36,964 new cases and 20,708 deaths due to cervical cancer. Hematological inflammatory parameters can reflect systemic inflammation that correlates with cancer severity. This study aimed to analyze the association between hematologic…
Background: Dry eye disease (DED) is a multifactorial disorder of the ocular surface characterized by the loss of tear film homeostasis. The prevalence of DED in Indonesia reaches 27.5%, with the evaporative type being the most common. Prolonged use of digital devices significantly contributes to the development of DED. Radiation emitted from digital screens is more easily absorbed by younger t…
Background. Urinary tract infection (UTI) is a common health problem among females and is strongly influenced by genital hygiene. Lack of knowledge and poor personal hygiene practices, especially among adolescent girls, can increase the risk of developing UTIs. Therefore, this study aimed to determine the relationship between the level of knowledge of genital hygiene and UTI prevention behavior…
Background: Cardiomegaly refers to an abnormal enlargement of the heart, which can be detected through various diagnostic methods, with echocardiography regarded as the gold standard. However, in patients who are bedridden, along with the limitations in healthcare infrastructure at some medical facilities, antero-posterior (AP) chest radiography serves as a more accessible alternative. This stu…
Medical students often face heavy academic burdens, high expectations for achievement, and difficulties in balancing studies with personal life. These conditions make them vulnerable to experiencing emotional mental disorders. However, awareness and intention to seek psychological help remain low. Seeking psychological help is an active effort to obtain support or treatment related to mental he…
Background: According to data released by the World Health Organization (WHO) in 2022, around 450,000 cases of TB-RO will occur throughout the world. In TB-RO patients there was an increase in the number of neutrophils and a decrease in the number of leukocytes. RNL calculations are carried out as an indicator that plays a role in reflecting the body's inflammatory response to infection. At the…
Background: Breast Milk is an essential source of nutrition for infants, containing micronutrients, macronutrients, and bioactive components that support their health and development. Breast milk consists of 87%-88% water, 7% lactose, 1% protein, and 3.8% fat, as well as various vitamins and antibodies that play a role in protecting infants from diseases. The composition of breast milk is influ…
Background: Hepatoma, or hepatocellular carcinoma, is the primary liver tumor accounting for 90% of liver tumor cases. In certain cases, hepatoma patients only undergo laboratory examinations without radiological imaging. An alternative method is needed to monitor tumor progression, predict patient prognosis, and determine appropriate treatment without radiological examinations, namely by measu…
Background: The most common superficial fungal skin disease, which has become a global health problem, is Tinea versicolor or Pityriasis versicolor. Personal hygiene behaviors were performed to maintain personal cleanliness and health. Several behaviors increased the risk of Pityriasis versicolor among scavengers, including not showering immediately after work, rarely changing work clothes, and…
Menopause is the cessation of menstruation for 12 consecutive months due to the loss of ovarian follicle function. Various factors can influence the menopausal process, such as dietary patterns, sleep patterns, stress levels, and physical activity. A study conducted by Mirrah in Palembang in 2023 revealed that 93.93% of women experienced menopausal symptoms. However, research on the relationshi…
Bakteri Klebsiella penumoniae dapat menyebabkan infeksi serius, terutama ketika sudah menyebar pada organ tubuh. Penggunaan antibiotik sering menjadi pilihan dalam menangani infeksi, namun bakteri dapat beradaptasi dengan membentuk biofilm. Senyawa antibiofilm yang biasa digunakan berbahan sintetik kimia yang dapat berdapak negatif pada manusia. Oleh karena itu, pencarian alternatif antibiofilm…
Background. Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, requiring rational pharmacological therapy. Metformin is the first-line therapy for type 2 DM as recommended by WHO and the National Formulary. Defined Daily Dose (DDD) measurement enables a quantitative evaluation of drug use. However, studies on DDD for metformin in South Sumatra remain limited.…
Cervical cancer is the main cause of cancer death among woman and the third most cancer case in the world. High expression of VEGF in cervical cancer is linked to a poor prognosis, therefore anti-VEGF therapy has an important role in cervical cancer resolution. Several studies show that emodin inhibit proliferation, migration, and a formation of endothelial cells stimulated by VEGF. This resear…
Infectious diseases are a major health problem in Indonesia, with antibiotics being the primary choice for treatment. However, inappropriate antibiotic use can lead to resistance, increasing morbidity, mortality, and healthcare costs. The World Health Organization (WHO) recommends the Defined Daily Dose (DDD) method to standardize and measure antibiotic use for effective monitoring. This study …
Introduction: Stroke is one of the leading causes of morbidity and mortality worldwide, including in Indonesia. Stroke can be categorized into two main types: ischemic stroke and hemorrhagic stroke, each influenced by various risk factors such as age, gender, history of hypertension, and cardiomegaly. This study aims to analyze the association between age, gender, history of hypertension, and c…
Sepsis is one of the leading causes of acute kidney injury (AKI). Ureum and creatinine testing is a routine diagnostic tool for acute kidney failure. This study aimed to analyze differences in ureum and creatinine levels across AKI stages in sepsis patients.This study is an analytic descriptive study using a cross sectional study design. Data were collected from the medical records of AKI sepsi…
Cervical cancer is a malignancy of the cervix wall with a high prevalence among women worldwide, ranking third after breast and colorectal cancer. The disease is primarily caused by Human Papillomavirus (HPV) infection, with HPV types 16 and 18 being the leading cause in more than 70% of cases. Cervical cancer patient survival is influenced by various factors, including stage, histopathology ty…
According to WHO, stunting is a condition where the TB/U Z-score is less than -2 SD. The problem that arises when children reach the age of 2 years is a critical period for growth disorders, including short stature or dwarfism. Genetic factors become the main foundation in achieving the final result of the child's growth and development process. The study untilized an analytic observational des…
Osteoarthritis (OA) is a degenerative joint disease of the joints characterized by cartilage destruction and thickening of the subchondral bone. Joint degeneration in osteoarthritis causes pain and stiffness, which limits joint movement. In Indonesia, the prevalence of osteoarthritis reaches 5% at age 61 years. Body mass index and physical activity are factors that can affect the severity of ge…
Pediatric transfusion-dependent thalassemia patients require lifelong transfusion to compensate for inadequate erythrocyte and to support patient’s growth and development. However, regular transfusion can cause iron overload leading to oxidative stress-induced liver injury. The purpose of this study is to analyze the relationship between iron overload and liver function in pediatric transfusi…
Hirschsprung disease (HSCR) is a congenital disorder of the large intestine resulting from missing nerve cells in the colon, leading to bowel obstruction. Despite surgical interventions, post-operative challenges, including constipation, incontinence, and emotional stress, can impact patients' quality of life. This study aims to evaluate the quality of life in school-aged HSCR patients post-sur…
One of the global health problems that is still neglected, especially in tropical and sub-tropical countries such as Indonesia, is soil-transmitted helminths (STH) infection. Scavengers who come into contact with the soil while working are a group that is vulnerable to STH contamination of the fingernails. This study aims to analyze the relationship between the level of personal hygiene and STH…
Acute Otitis Media (AOM) is a condition characterized by inflammation of the middle ear mucosa, the Eustachian tube, antrum antrum, and mastoid cells, caused by bacteria or viruses. AOM is marked by the presence of fluid and/or inflammation in the middle ear. If a persistent perforation occurs with continuous discharge, it can lead to further complications, such as chronic suppurative otitis me…
Background: Epicanthus is a fold of skin at the nasal bridge and upper eyelid that covers the medial canthus. This condition is common in Asian populations (40–90%) but rare in non-Asians (2–5%). Epicanthus may represent a normal anatomical variation or be associated with syndromes such as Down syndrome, Turner syndrome, or blepharophimosis syndrome. Types of epicanthus include tarsal, palp…