Background: Purple sweet potato (Ipomoea batatas L.) is some type of potatoes that commonly used as an alternative for rice. Eventhough purple sweet potato was known to had phytopharmacal potentials, there is still few scientific literatures about the using of purple sweet potato as a therapeutic choice for renal fibrosis. This study is aimed to measure the efficacy of purple sweet potato extra…
Staphylococcus aureus is one of the most common bacterial infections in humans and is the causative agent of many human infections including bacteremia and sepsis. The use of antibiotics is a way of management, but excessive use can increase resistance. This study aims to see the effectiveness of antibacterial growth of ethanol extract of Carica papaya L. flowers on the inhibition of S.aureus A…
This research constitutes an experimental analytic study conducted in vivo, employing two parameters. The investigation of total cholesterol levels was conducted using a pre-test and post-test design with a control group. Conversely, the study of hepatic histology utilized a post-test with a control group design. Thirty male mice were allocated into five groups: a negative control, an obesity c…
Background: Indonesia's biodiversity is one of the features of our country. There are many plants with various potentials and benefits, including for health. One plant that can be used as an alternative treatment is the cherry plant. The benefits of the cherry plant are due to the secondary metabolite compounds it contains which can inhibit xanthine oxidase enzyme. Mistletoe can have the same c…
Background: Gout arthritis is an inflammatory disease of the joints caused by the deposition of monosodium urate crystals in the joint area, especially the extremities. In pharmacological therapy, allopurinol is the first-line choice in the management of gout, especially asymptomatic, intercritical, and chronic hyperuricemia phases. In Indonesia, especially now there is no data discussed gout a…
Background: Patient adherence is the key to success in the treatment of endometriosis. Monitoring of drug side effects needs to be done in order to obtain appropriate treatment results. Patients need to know information about the presence of side effects of leuprolide acetate injection drugs. This study was conducted to determine the incidence of side effects of using leuprolide acetate injecti…
Background: Over-the-counter drug (OTC) is a medicine that can be purchased freely without a doctor's prescription. Students tend to need medicine that can be accessed quickly and efficiently. Thus, the majority of population who do self-medication is mostly students. Unfortunately, there are still many people who do self-medication without being given sufficient education, so knowledge, attitu…
Background. Kersen leaf extract has the effect of inhibiting the xanthine oxidase enzyme and cherry mistletoe leaves also have the same properties considering that they are hemiparasites with their host. This study aims to determine the effect of n-hexane extract from mistletoe cherry leaves on the xanthine oxidase enzyme. Method. This research is an in vitro experimental research. The samples …
Background: Urinary tract infection (UTI) is one of the etiologies of febrile neutropenia (FN) in pediatric malignancy, an oncology emergency. Empirical antibiotic prescribing according to guidelines, based on local bacterial and resistance patterns, should be initiated immediately. This study aims to determine the prevalence of UTI, the distribution of bacterial and antibiotic sensitivity patt…
Background: Esophageal varices is the most life-threatening complication of portal hypertension in hepatic cirrhosis patients. Around 80% of cirrhosis patients will eventually experience this complication. Non-invasive parameters are needed for early detection of the degree of esophageal varices so that patients with severe varices can be immediately referred for endoscopic examination. In addi…
Introduction: Obesity is characterized by the abnormal accumulation of fat within the body, resulting from an imbalance between the energy intake and expenditure. Obesity elevates the risk of various chronic diseases, necessitating efforts to prevent and treat this condition. Previous research has revealed that Moringa oleifera leaf extract contains polyphenolic compounds with advantageous prop…
Background: Preeclampsia is the state of pregnant women experiencing hypertension with a systolic blood pressure of 140 mmHg or diastolic blood pressure of 90 mmHg and proteinuria totaling ≥ 300 mg. Nifedipine can be given to pregnant women with preeclampsia. Antihypertensive drugs of the calcium channel blocker group, namely nifedipine, are one of the drugs that are often used because of the…
The shift in disease burden from Communicable Diseases (PM) to Non-Communicable Diseases (PTM) has occurred in the last three decades. Cardiovascular disease is the second level with the number of deaths from non-communicable diseases reaching 17.8 million (31%) deaths every year of the world's mortality rate. In Indonesia, the highest mortality from NCDs is caused by heart disease which reache…
Background: Periodontitis is an oral cavity disease with a very high prevalence in Indonesia. Periodontitis can cause loose teeth and easy detachment. Robusta coffee extract Semendo contains active compounds as antiinflammatory and antibacterial agents that can reduce the number of PMN cells in chronic periodontitis treatment. Objective: To determine the effectiveness of robusta coffee extract …
Latar Belakang: Prosedur insisi dapat menyebabkan luka yang dapat sembuh melalui proses penyembuhan yang terdiri dari 4 fase berurutan. Cangkang telur bebek merupakan sumber kalsium dan protein. Pemanfaatan cangkang telur bebek merupakan salah satu cara untuk meningkatkan jumlah fibroblas dan mempercepat proses penyembuhan luka. Tujuan: Mengetahui efektivitas ekstrak cangkang telur bebek konsen…
KIN THAT IS EXPOSED TO EXCESSIVE SUN EXPOSURE CAN RESULT IN SEVERAL LOSSES THAT CAN DAMAGE THE SKIN INCLUDING PREMATURE AGING, SKIN DAMAGE BY ULTRAVIOLET RADIATION, AND SUNBURN OR BURNING REACTIONS. SUNSCREEN IS NEEDED TO PROTECT THE SKIN FROM DAMAGE CAUSED BY UV RAYS. ZINC OXIDE IS A PHYSICAL SUNSCREEN AGENT THAT IS OFTEN USED AS AN ACTIVE INGREDIENT IN SUNSCREEN PREPARATIONS. AVOCADO LEAVES H…
Daun sambiloto (Andrographis paniculata (Burm.f.) Nees) merupakan tanaman yang mengandung senyawa aktif seperti andrografolida (diterpenlactone), flavonoid, asam quinic, steroid, saponin, alkaloid dan tanin yang memiliki potensi sebagai antiinflamasi, antioksidan, antibakteri, dan mempercepat penyembuhan luka. Penelitian ini bertujuan untuk mengoptimasi Gelling Agent pada sediaan gel ekstrak sa…
Daun sukun (artocarpus altilis) dilaporkan memiliki kandungan flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh variasi dosis terhadap efek nefroprotektif. Parameter yang diamati meliputi volume urin, pH urin, kreatinin serum, ureum serum, protein urin, klirens kreatinin, serta dilakukan …
Kenikir leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds in the form of quersetin which can become the α-glukosidase enzyme inhibitor so that excess blood glucose level can be lowered. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option for improving the delivery system whi…
Soursop leaf and sapodilla leaf contain secondary metabolit is flavonoid which is antioxidant. The study aimed to the characteristic of the ethanol extract soursop leaf (Annona muricata L.) and sapodilla leaf (Manilkara zapota L.), total flavonoid contents, and antioxidant activity of combine ethanol extract soursoup leaf and sapodilla leaf using DPPH method. The treatment of antioxidant activi…