Background: The spine is the central supporting structure of the body. Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional structural deformity of the spine that occurs in adolescents 10-17 years old which is characterized by lateral curvature in the frontal plane, thoracic lordosis in the sagittal plane, and rotation of the vertebrae in the transverse plane, with a Cobb angle reaching…
Background: Anemia in pregnancy is a common maternal health problem contributing to prematurity, morbidity, and maternal–infant mortality. Low hemoglobin leads to placental hypoxia, HPA-axis activation, and increased prostaglandins that trigger early uterine contractions. This study analyzed the association between anemia and prematurity at RSUP Dr. Mohammad Hoesin Palembang. Methods: This an…
Background: Candy is a processed food in the form of a solid and if consumed excessively it will reduce the salivary pH which is one of the factors causing caries. This decrease occurs due to the activity of acid-producing bacteria in the oral cavity. Preventing a decrease in salivary pH can be done by adding gambir and xylitol to candy. Gambir is a herbal ingredient containing catechins and ta…
Background: The liver is susceptible to damage due to exposure to free radicals, which trigger oxidative stress. This condition increases AST and ALT enzymes, which are markers of liver injury. This study used CCl₄-induced Wistar rats as a model of liver damage. Antioxidants are needed to prevent damage, and silymarin was used as a positive control. Purple sweet potato leaf extract contains f…
Background. Endometrial carcinoma is a gynecological malignancy originating from the endometrial lining of the uterus. It ranks as the sixth most common cancer among women worldwide, and its incidence is associated with excessive estrogen exposure to the endometrium. This study aims to describe the risk profile and therapeutic modalities of patients with endometrial carcinoma treated at RSUP Dr…
Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a wide spectrum of clinical manifestations, ranging from mild cutaneous abnormalities to severe organ dysfunction. Previous studies have shown a decrease in lymphocyte count, or lymphopenia, in SLE patients, which is often associated with disease activity. However, research on the relationship betwee…
Background: Hypospadias is the second most common congenital anomaly found in males after cryptorchidism, with urethrocutaneous fistula being the most frequent postoperative complication. The incidence rate of urethrocutaneous fistula is one of the indication of the success of hypospadias management. The age at surgery is suspected to play a role in determining the treatment outcome. However, r…
Komplikasi umum yang dapat terjadi selama kehamilan adalah hipertensi, termasuk preeklampsi, hipertensi gestasional, dan hipertensi kronis, yang mempengaruhi hingga 10% kehamilan. Hipertensi yang tidak ditangani dengan baik dapat menyebabkan berbagai masalah kesehatan serius bagi ibu dan janin, seperti penyakit arteri koroner, penyakit ginjal kronis, dan hambatan pertumbuhan janin. Komplikasi a…
Introduction: S. aureus is one of the most frequently found and detected microorganisms in odontogenic infections of oral and cerebral abscesses. The treatment of odontogenic infections can be treated using antibiotics, which can be replaced by honey. Tembesu bitter black honey is a natural material that can be used as an antibacterial because it has high osmolarity, low pH (3,2-4,5), low water…
Introduction: Chronic Kidney Disease (CKD) is a chronic kidney disease that causes the accumulation of fluids, electrolytes, and waste in the body, which affects sleep patterns. In nursing interventions, the use of sleep support in the form of Progressive Muscle Relaxation (PMR) is a technique performed by contracting and stretching muscles to provide relaxation effects and address sleep distur…
Dysmenorrhea is a common complaint among young adult women that can impair quality of life and academic performance. The prevalence of dysmenorrhea in Indonesia reaches 64.25%. Calcium, as an essential micronutrient, is believed to play a role in women's reproductive health; however, calcium intake among young women in Indonesia remains below the Recommended Dietary Allowance. Previous studies …
Introduction. Low back pain (LBP) is a common musculoskeletal complaint influenced by various risk factors. Yoga, as a non-pharmacological therapy, is known to help improve LBP symptoms. This study aimed to determine the characteristics of LBP and the profile of yoga practice in community X in Palembang City. Methods. This study was a descriptive observational study with a cross-sectional appro…
Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis infection in children, often leading to neurological disability and death. Diagnosis is frequently delayed due to nonspecific symptoms and limited diagnostic resources in healthcare settings. This study aimed to describe the clinical characteristics of pediatric TBM patients at Mohammad Hoesin General Hospital, Pal…
Background: Cholestasis is a condition characterized by impaired bile formation and/or obstruction of bile flow, commonly occurring within the first three months of life. The age at presentation influences the clinical outcomes of infants with cholestasis. Infants presenting after three months of age have surpassed the ideal period for early detection and evaluation of cholestasis as recommende…
Background: Tuberculosis (TB) is an infectious disease that remains a major global health problem, including in Indonesia. One of the most common forms of extrapulmonary TB is tuberculous pleurisy, which is characterized by pleural fluid accumulation due to a hypersensitivity reaction triggered by Mycobacterium tuberculosis infection. Diagnosis is established through clinical examinations, radi…
Background: Craniomaxillofacial fractures are among the most common trauma cases found in emergency departments, often leading to functional, aesthetic, and psychological impairments. These conditions can significantly affect the patient’s quality of life even after reconstructive surgery. However, studies examining the relationship between patient characteristics and post-reconstruction qual…
Background: Osteoarthritis (OA) is one of the most common degenerative diseases of chronic musculoskeletal disorders, particularly in the elderly. The prevalence of knee osteoarthritis is higher compared to other joint OA. Clinical symptoms experienced by patients with knee OA include pain, stiffness, and limited range of motion (ROM), which lead to decreased physical function, difficulties in …
Background: Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that frequently causes nosocomial infections and exhibits strong biofilmforming ability as well as high resistance to various antibiotics, including carbapenems. The increasing incidence of MDR-P. aeruginosa highlights the need for alternative antimicrobial agents derived from natural sources. Karamunting leaves (Rhod…
Background: Hyperglycemia in type 2 DM, characterized by elevated HbA1c, can cause diabetic dyslipidemia, which increases cardiovascular risk. Various atherogenic indices are used to predict this risk. This study aims to analyze the correlation of HbA1c with atherogenic index of plasma (AIP), atherogenic coefficient (AC), and Castelli risk index (CRI) in type 2 DM patients. Methods: This observ…
Background. ST Elevation Myocardial Infarction (STEMI) is the most severe form of acute coronary syndrome caused by total occlusion of the coronary artery, leading to myocardial ischemia and necrosis. Blood pressure in the early phase of STEMI reflects the patient’s hemodynamic condition and plays an important role in determining clinical outcomes. Measuring blood pressure upon hospital admis…
Background: Endometrial carcinoma is an epithelial malignancy that occurs in the endometrium, the innermost layer of the uterine wall. Endometrioid endometrial carcinoma is the most common histopathological type of endometrial carcinoma. This type is associated with estrogen exposure without progesterone (unopposed estrogen) and risk factors such as advanced age, obesity, and nulliparity. Study…
Background: Adiposity indices are anthropometric measures used to assess the amount and distribution of body fat. Changes in fat distribution may influence the morphology of various body parts, including the auricle. The auricle exhibits variations in shape and size that may reflect changes in adipose tissue composition. This study aims to determine the relationship between adiposity indices an…
Background: Coronary Artery Disease (CAD), particularly Acute Coronary Syndrome (ACS) with ST-Elevation Myocardial Infarction (STEMI), is a leading cause of morbidity and mortality worldwide. Coronary artery occlusion in STEMI patients disrupts blood flow to the myocardium, triggering clinical symptoms such as angina, dyspnea, arrhythmias, and cardiogenic shock. This study aims to analyze the r…
Background. Laryngopharyngeal reflux (LPR) is a pathological condition caused by the backflow of stomach contents into the larynx and pharynx, causing symptoms in the upper respiratory tract. One of the suspected risk factors is caffeine consumption, as it can decrease lower esophageal sphincter pressure and increase gastric acid secretion. Medical students tend to consume caffeinated beverages…
Background: Acute ischemic stroke is a major cause of global morbidity and mortality. Systemic inflammation plays a key role in its pathogenesis, and the neutrophil-to-lymphocyte ratio (NLR) is used as an inflammatory indicator. Elevated NLR is suspected to correlate with stroke severity assessed using the NIHSS. Methods: This retrospective observational analytic study used medical records of a…
Mosquitoes are vectors of infectious diseases such as dengue fever, malaria, and filariasis. Their breeding activity is strongly influenced by environmental factors, particularly the physical and chemical characteristics of water in potential breeding containers. This study aimed to analyze the correlation between water’s physical and chemical conditions and the number of mosquito larvae in B…
Kenikir leaves (Cosmos caudatus) contain various bioactive compounds and have a relatively high total protein content compared to other plant leaves. Ammonium sulfate precipitation is one of the common methods applied for protein isolation. However, there are currently no available data comparing the protein content and purity of kenikir leaves proteins precipitated with different concentration…
Background: Impetigo is a superficial skin infection in children mainly caused by Staphylococcus aureus. Although mupirocin is effective, long-term use may cause side effects and resistance. The pineapple core (Ananas comosus L. Merr.) contains bioactive compounds with potential antibacterial effects against S. aureus. This study aimed to evaluate the efficacy of pineapple core extract on the i…
Chronic Suppurative Otitis Media (CSOM) is a persistent middle ear infection characterized by tympanic membrane perforation and ear discharge, which may lead to hearing impairment and serious complications. This study aimed to determine the association between risk factors and comorbidities with the type of CSOM at the ENT-HN Department of Dr. Mohammad Hoesin General Hospital Palembang in 2025.…
Background: Pleural effusion is a common clinical manifestation encountered in internal medicine and pulmonology practice, with various etiologies, both transudative and exudative. In Indonesia, the most frequent causes of pleural effusion are tuberculosis, followed by malignancy and heart failure. Analysis of patient characteristics and pleural fluid is essential to determine the type of effus…