The shift in disease burden from Communicable Diseases (PM) to Non-Communicable Diseases (PTM) has occurred in the last three decades. Cardiovascular disease is the second level with the number of deaths from non-communicable diseases reaching 17.8 million (31%) deaths every year of the world's mortality rate. In Indonesia, the highest mortality from NCDs is caused by heart disease which reache…
Background: Periodontitis is an oral cavity disease with a very high prevalence in Indonesia. Periodontitis can cause loose teeth and easy detachment. Robusta coffee extract Semendo contains active compounds as antiinflammatory and antibacterial agents that can reduce the number of PMN cells in chronic periodontitis treatment. Objective: To determine the effectiveness of robusta coffee extract …
Latar Belakang: Prosedur insisi dapat menyebabkan luka yang dapat sembuh melalui proses penyembuhan yang terdiri dari 4 fase berurutan. Cangkang telur bebek merupakan sumber kalsium dan protein. Pemanfaatan cangkang telur bebek merupakan salah satu cara untuk meningkatkan jumlah fibroblas dan mempercepat proses penyembuhan luka. Tujuan: Mengetahui efektivitas ekstrak cangkang telur bebek konsen…
KIN THAT IS EXPOSED TO EXCESSIVE SUN EXPOSURE CAN RESULT IN SEVERAL LOSSES THAT CAN DAMAGE THE SKIN INCLUDING PREMATURE AGING, SKIN DAMAGE BY ULTRAVIOLET RADIATION, AND SUNBURN OR BURNING REACTIONS. SUNSCREEN IS NEEDED TO PROTECT THE SKIN FROM DAMAGE CAUSED BY UV RAYS. ZINC OXIDE IS A PHYSICAL SUNSCREEN AGENT THAT IS OFTEN USED AS AN ACTIVE INGREDIENT IN SUNSCREEN PREPARATIONS. AVOCADO LEAVES H…
Daun sambiloto (Andrographis paniculata (Burm.f.) Nees) merupakan tanaman yang mengandung senyawa aktif seperti andrografolida (diterpenlactone), flavonoid, asam quinic, steroid, saponin, alkaloid dan tanin yang memiliki potensi sebagai antiinflamasi, antioksidan, antibakteri, dan mempercepat penyembuhan luka. Penelitian ini bertujuan untuk mengoptimasi Gelling Agent pada sediaan gel ekstrak sa…
Daun sukun (artocarpus altilis) dilaporkan memiliki kandungan flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh variasi dosis terhadap efek nefroprotektif. Parameter yang diamati meliputi volume urin, pH urin, kreatinin serum, ureum serum, protein urin, klirens kreatinin, serta dilakukan …
Kenikir leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds in the form of quersetin which can become the α-glukosidase enzyme inhibitor so that excess blood glucose level can be lowered. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option for improving the delivery system whi…
Soursop leaf and sapodilla leaf contain secondary metabolit is flavonoid which is antioxidant. The study aimed to the characteristic of the ethanol extract soursop leaf (Annona muricata L.) and sapodilla leaf (Manilkara zapota L.), total flavonoid contents, and antioxidant activity of combine ethanol extract soursoup leaf and sapodilla leaf using DPPH method. The treatment of antioxidant activi…
Skizofrenia merupakan salah satu ganggu jiwa berat yang ditandai dengan kesulitan pada penderita untuk membedakan antara nyata dan tidak nyata dalam kehidupan sehari-hari seperti halusinasi dan delusi. Manajemen terapi yang digunakan pada pasien skizofrenia adalah menggunakan terapi antipsikotik. Efek samping yang sering muncul akibat terapi antipsikotik adalah gejala ekstrapiramidal. Penelitia…
Gout is an arthritis disease that occurs due to increased levels of uric acid in the blood (hyperuricemia), causing the deposition of monosodium urate (MSU) crystals in the joints. Rational drug use in gout patients can affect the success of therapy. This study aims to determine the correlation between the rationality of drug use and clinical outcomes in gout patients at RSI Siti Khadijah Palem…
Ekstrak etil asetat daun nangka (Artocarpus heterophyllus) mengandung senyawa metabolit sekunder berupa flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan mengetahui aktivitas perbaikan fungsi ginjal dari ekstrak etil asetat daun nangka (EEADN). Uji aktivitas perbaikan ginjal dilakukan selama 28 hari menggunakan 30…
Breadfruit leaves (Artocarpus altilis (Park.) Fosberg) contain flavonoids which have activity and have the potential to act as photoprotective agents because of their ability to absorb UV light. This study aims to determine the effect of variations in the formulation of breadfruit leaf ethyl acetate extract on the effect of activity tests as a sunscreen with Carbomer 940 and Triethanolamine as …
Exposure to direct sunlight for a long time can cause damage to the epidermal tissue of the skin which is a factor in the emergence of erythema and causes skin cancer. Sunscreen is a cosmetic product that functions to protect the skin from exposure to UV rays. Breadfruit leaves (Artocarpus altilis) are reported to contain antioxidant compounds which have the potential to be active ingredients f…
Sambiloto leaves extract (Andrographis paniculata (Burm.f.) Wall. Ex Ness) contains andrographolid and flavonoid main secondary metabolites which have potential as ultraviolet radiation protection and antioxidant activity as photoprotective agents. This research aims to determine the optimization of Tween 80 and Ethanol 96% concentrations to increase their photoprotective and stability. Optimiz…
Daun cempedak (Artocarpus champeden) mengandung metabolit sekunder berupa flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi dalam memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etil asetat daun cempedak (EEADC) terhadap volume dan pH urin, kadar kreatinin dan ureum serum, kadar protein urin, klirens kretinin dan gamb…
Catechins compounds in gambier leaves have an antioxidant effect. The purpose of this study is to determine the optimal results of gambir leaf extract and the characteristic of optimal gambier leaf extract. The extraction method used in the study was ultrasoundassisted extraction (UAE). Data analysis was carried out using software design expert 13 with factorial 23. Factors in the extraction pr…