PREPARASI DAN UJI ANTINEFROLITIASIS FRAKSI ETANOL DAUN KERSEN (Muntingia cala…

Daun kersen (Muntingia calabura L.) diketahui memiliki efek farmakologi sebagai antinefrolitiasis karena mengandung senyawa flavonoid yang dapat berikatan dengan kalsium pada batu ginjal dan meningkatkan ekskresi urin. Senyawa bahan alam mempunyai kelarutan dan bioavailabilitas yang rendah dalam air sehingga dapat diatasi dengan inovasi sediaan berupa nanosuspensi. Penelitian ini bertujuan untu…

UJI ANALGETIKA DAN ANTIINFLAMASI EKSTRAK DAN FRAKSI DAUN ASAM KANDIS (Garcini…

Asam kandis (Garcinia parvifolia (Miq.) Miq) merupakan tanaman tropis yang termasuk dalam famili Clusiaceae, yang banyak digunakan dalam pengobatan tradisional di Indonesia dan daerah tropis lainnya. Penelitian ini bertujuan untuk mengevaluasi efek analgetika dan antiinflamasi dari ekstrak dan fraksi daun asam kandis (Garcinia parvifolia (Miq.) Miq) pada tikus putih jantan. Penelitian ini mengg…

UJI TOKSISITAS SUBKRONIS EKSTRAK ETANOL DAUN SUKUN (ARTOCARPUS ALTILIS) PADA …

Daun sukun (Artocarpus altilis) merupakan salah satu tanaman obat potensial dengan berbagai khasiat. Namun, penggunaan daun sukun sebagai obat tradisional belum diketahui tingkat keamanannya. Penelitian ini bertujuan untuk mengetahui efek toksisitas subkronis ekstrak etanol daun sukun (Artocarpus altilis) pada tikus putih galur wistar. Pengujian dilakukan selama 28 hari dengan pemberian sediaan…

FORMULASI SELF-NANO EMULSION EKSTRAK GETAH GAMBIR (UNCARIA GAMBIR ROXB.) MENG…

The main component of polyphenolic compounds in gambier sap extract is catechin, a flavonoid compound with anti-inflammatory properties that can help relieve inflammatory. Catechins have low solubility and bioavailability, resulting in its to deliver into the body. In this research, gambier sap extract was formulated using a drug delivery technology system in the form of Self-Nano Emulsion syst…

UJI AKTIVITAS PENYEMBUHAN LUKA BAKAR DAN LUKA SAYAT DARI EKSTRAK ETANOL DAUN …

Lawsonia inermis is a traditional medicinal plant used to treat inflammation of the finger joints and skin diseases.The aims of This study were evaluated the efficacy of Lawsonia inermis leaf extract in healing burn and incision wounds. The extraction was carried out using the maceration method with ethanol solvent.The research were used 60 male Wistar rats, divided into six treatment groups (f…

PENGUJIAN EKSTRAK DAN FRAKSI DAUN GELAM (Melaleuca leucadendra L.) SEBAGAI AN…

Pain and inflammation are common health issues experienced by patients. Non-steroidal anti-inflammatory drugs (NSAIDs) are often used to treat these conditions, but they come with undesirable side effects. Traditional medicine using Gelam leaves (Melaleuca leucadendra L.) may offer a promising alternative with potential analgesic and anti-inflammatory properties. Secondary metabolites in Gelam …

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI DAUN JARAK PAGAR (Jatropha curca…

Jatropha curcas linn leaves contain secondary metabolite compounds such as alkaloids, flavonoids (kaemperol), saponins, steroids, tannins, quinones, and phenols. Empirically, this study aims to determine the characteristics and phytochemical screening of ethanol extracts and fractions of Jatropha curcas leaves, the effect of administering ethanol extracts and fractions on MDA levels, catalase e…

UJI AKTIVITAS PENYEMBUHAN LUKA BAKAR DAN LUKA SAYAT DARI EKSTRAK ETANOL BUNGA…

Purple Paper Flower (Bougainvillea spectabilis) has traditionally been used to treat various diseases such as hepatitis, ulcers, vaginal discharge, and irregular menstruation. Its secondary metabolite compounds include alkaloids, flavonoids, phenols, quinones, saponins, steroids, tannins, and terpenoids, which have potential to accelerate wound healing. This study aims to identify the character…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL TANAMAN TAKOKAK (Solanum torvum Sw.)

The Takokak plant (Solanum torvum Sw.) contains phenolic compounds, flavonoids, glycosides, tannins, sterols, saponins, alkaloids, triterpenes, anthraquinones, and anthocyanins, which have potential as natural antioxidants. This study aimed to determine the total phenolic and flavonoid content, antioxidant activity (IC50), and inhibition percentage of ethanol extracts from the roots, flowers, f…

UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN SUKUN (ARTOCARPUS ALTILITIS (PARK.) F…

Breadfruit leaves (Artocarpus altilitis) are one of the herbal medicines that have activity as antihyperglycemia, antibacterial, anti-inflammatory, and antihypertensive. From the results of phytochemical screening, it is known that ethanol extract of breadfruit leaves contains phenolics, saponins, tannins, flavanoids, polyphenols, hydrocyanic acid, acetylcholine, riboflavin. The safety of using…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI DAUN BANDOTAN (Ageratum conyzoid…

Bandotan leaves are known to contain alkaloids, flavonoids, tannins, saponins, triterpenoids, steroids, and phenolics. This research aims to analyze the characteristics, phytochemical composition, impact of administration of ethanol extracts and bandotan leaf fractions on antioxidant activity. The assessed parameters include MDA levels, catalase enzyme activity, macroscopic liver observations a…

Farmasi Fisik: DASAR-DASAR KIMIA FISIK DALAM ILMU FARMASETIK, EDISI KETIGA 1

Edition

3

ISBN/ISSN

979-456-031-6

Collation

722 hlm. : ilus. ; 23 cm

Series Title

-

Call Number

615.4 Mar f

FARMASI KLINIS (Kegiatan dan Keterampilan Tenaga Kefarmasian)

Edition

-

ISBN/ISSN

978-623-02-2355-6

Collation

vi, 58 hlm. ; 23 cm

Series Title

-

Call Number

615.4 Dew f

BIOFARMASETIKA: Pengantar Ilmu Biofarmasi

Edition

-

ISBN/ISSN

978-623-02-5859-6

Collation

viii, 70 hlm.; 23 cm

Series Title

-

Call Number

615.1 Ind b

Karakterisasi Sediaan Padat Farmasi

Edition

-

ISBN/ISSN

978-602-475-362-7

Collation

x, 182 hlm.; 20 cm

Series Title

-

Call Number

615.1 Sop k

AKTIVITAS ANTIDIABETES EKSTRAK DAN FRAKSI BUAH KARAMUNTING (Rhodomyrtus tomen…

Penelitian aktivitas antidiabetes ekstrak dan fraksi buah karamunting (Rhodomyrtus tomentosa (Aiton) Hassk) terhadap tikus putih jantan galur wistar terinduksi streptozotosin bertujuan mengetahuipengaruhpemberianekstraketanoldan fraksi etil asetat buah karamuntingterhadappenurunankadarglukosadarahtikusdiabetes mellitus tipe-2 dan mengetahuidosisefektifdarivariasiekstraketanol dan fraksi etil as…

STUDI IN SILICO POTENSI SENYAWA PADA DAUN SIRIH (Piper betle L.) SEBAGAI AGEN…

Hyperlipidemia is characterized by increased normal levels of plasma lipids such as cholesterol, triglycerides, cholesterol esters, phospholipids, and sometimes plasma lipoproteins, including very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL), along with decreased high-density lipoproteins (HDL). This study used an in silico approach to predict the molecular potential of be…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN ALPUKAT (PERSEA AMERICANA), DAUN JAMBU…

Long-term exposure to excess free radicals in the body can cause oxidative stress and various diseases, so antioxidant compounds are needed to neutralize free radicals. This research was conducted to determine the strongest antioxidant activity of avocado leaves, water guava leaves and cherry leaves which have been used empirically by the Ogan Ilir community. The extract with the strongest anti…

KARAKTERISASI DISPERSI PADAT IBUPROFEN DENGAN KITOSAN DAN VARIASI NATRIUM ALG…

Ibuprofen Is Classified As A Bcs Class Ii Biopharmaceutical. This Means That Researchers Use Solid Dispersion To Improve Its Solubility And Dissolution Rate, As It Has Poor Oral Solubility And Bioavailability. This Study Used A Combination Of Chitosan And Sodium Alginate To Form Solid Dispersion With Co-Grinding Technique, Which Is Easy To Do And Environmentally Friendly. In The Preparation Of …

EFEK PEMBERIAN SELF-NANO EMULSION EKSTRAK GAMBIR (UNCARIA GAMBIR ROXB) TERHAD…

Hyperlipidemia is a disorder of the fat metabolism system which causes an increase in total cholesterol, LDL, triglyceride levels and a decrease in blood HDL. Catechin is the main compound from gambier leaves, including flavonoid compounds which can reduce hyperlipidemia. The aim of this research was to determine the effect of administering self-nano emulsion from gambier leaf extract on lipid …

FORMULASI DAN PENGARUH ORALLY DISSOLVING FILM DARI TEPUNG AKAR CIKORI (Cichor…

Cikori root flour (Cichorium intybus L.) is a functional food containing inulin and is useful as a prebiotic in stimulating the growth of Bifidobacterium longum (B. longum). Prebiotic cikori root flour is made into an orally dissolving film (ODF) with the advantage of fast onset without interfering with the release of active ingredients with a pleasant taste. Research was conducted to see the p…

OPTIMASI ORALLY DISSOLVING FILM (ODF) ASAM USNAT DENGAN POLIMER HYDROXYPROPYL…

Asam usnat mempunyai kelarutan yang rendah dalam air, sehingga menyebabkan asam usnat agak sulit diformulasi. Salah satu cara untuk meningkatkan kelarutan asam usnat adalah dengan menggunakan sistem dispersi padat. Sistem dispersi padat orally dissolving film dipilih karena ODF mampu meningkatkan bioavailabilitas sistemik diperoleh dengan cara melewati first pass effect. Orally dissolving film …

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN MAHONI (Swietenia ma…

Mahogany leaves contain flavonoid, phenolic, triterpenoid, steroid, tannin and saponin compounds as antioxidants. This study aims to determine the characteristics, phytochemical screening, the effect of giving ethanol extracts and fractions of mahogany leaves on antioxidant activity with parameters of MDA levels, catalase enzyme activity, macroscopic and histopathological images of rat liver in…

OPTIMASI DAN KARAKTERISASI NANOEMULSI ERITROMISIN DENGAN VARIASI KONSENTRASI …

Erythromycin is a topical antibiotic with anti-inflammatory and immunomodulatory activities used for the therapy of mild to moderate inflammatory acne. However, conventional topical erythromycin formulations are still ineffective as they struggle to penetrate deeper into the sebaceous areas located in the dermal layer of the skin. Therefore, it is necessary to develop a topical formulation inco…

POTENSI EKSTRAK ETANOL DAN FRAKSI DAUN ASAM KANDIS (GARCINIA PARVIFOLIA (MIQ.…

The kandis tamarind plant is a plant that contains secondary metabolites such as flavonoids, phenolics, steroids, triterpenoids, saponins and tannins that have potential as antioxidants.The purpose of the study was to determine the characteristics and screening of kandis tamarind leaves, the effect of giving ethanol extracts and fractions of kandis tamarind leaves on MDA levels, catalase enzyme…

OPTIMASI KONSENTRASI CREMOPHOR RH 40 DAN ETANOL 96% DALAM FORMULASI SEDIAAN N…

Breadfruit leaves (Artocarpus altilis (Parkinson) Fosberg) contain the main flavonoid compound in the form of quercetin which has potential as an antiosteoarthritis. Nanoemulsion preparation is carried out to increase drug stability and penetration. This research aims to determine the optimum concentration of Cremophor RH 40 and Ethanol 96% using the factorial 22. The optimum formula is determi…

EFEK PEMBERIAN SELF-NANO EMULSION (UNCARIA GAMBIR ROXB.) TERHADAP PROFIL NEUR…

Diabetes mellitus (DM) can cause cognitive disorders and even Alzheimer's disorders. Catechins in gambier have pharmacological effects as antioxidants and can be used as therapy to improve cognitive function and prevent Alzheimer's disease. The research aims to determine the characteristics of gambier extract and SNE as active anti-diabetic ingredients to prevent Alzheimer's disease and to dete…

OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI TRANSETOSOM FRAKSI ETIL ASETAT DAUN SI…

Cassava leaves (Manihot Esculenta Crantz.) is proven to contain secondary metabolites, including flavonoids such as rutin, which demonstrated antibacterial capabilities. The deformability and elasticity of transethosomes penetrated the stratum corneum and increased the transfer of active substances in skin permeability. This research aimed to determine the optimum transethosome formula from var…

OPTIMASI DAN KARAKTERISASI NANOEMULSI ERITROMISIN DENGAN VARIASI KONSENTRASI …

Erythromycin is a drug classified into Biopharmaceutical Classification System (BCS) class II which has low solubility in water so that it can reduce the speed of drug penetration into skin. One of the efforts to increase the penetration of Erythromycin is to formulate erythromycin into a nanoemulsion delivery system. The nanoemulsion was prepared by the PIT (Phase Transition Temperature) metho…

OPTIMASI FORMULA NANOSTRUCTURED LIPID CARRIER EKSTRAK KULIT JERUK MANIS (Citr…

The utilization of sweet orange peel is still minimal as it is often overlooked after fruit processing for consumption, despite being rich in bioactive compounds, including flavonoids, especially for topical preparations. Previous research has mainly focused on conventional formulations with limitations in skin penetration. The Nanostructured Lipid Carrier (NLC) delivery system can enhance perc…