Melinjo leaves (Gnetum gnemon L.) have been widely researched in their use as an efficacious medicinal plant. Flavonoid as secondary metabolite compounds contained in melinjo leaves have the potential to be antioxidants. Antioxidant activity test on the ethanol fraction of melinjo leaves was tested with in vivo method with the aim of determining its effect on malondialdehyde (MDA) levels, catal…
Rimpang temulawak mengandung senyawa metabolit sekunder berupa flavonoid, steroid, triterpenoid dan tannin. Penelitian ini bertujuan untuk mengetahui efek gastroprotektif ekstrak etanol rimpang temulawak melalui parameter makroskopik lambung, volume, pH, keasaman total cairan lambung, kadar mucin, serta pengamatan mikroskopik. Tikus dibagi menjadi 6 kelompok yaitu kelompok normal, kontrol posit…
Ketidakseimbangan antara jumlah radikal bebas dan antioksidan endogen tubuh menimbulkan stress oksidatif yang dapat menyebabkan kerusakan sel. Tubuh memerlukan asupan antioksidan dari luar tubuh, baik sintetis atau alami. Salah satu sumber antioksidan alami adalah daun salam yang mengandung flavonoid yang dapat menstabilkan radikal bebas. Pengujian aktivitas antioksidan fraksi etil asetat daun …
Purple sweet potato leaves contain alkaloids, flavonoids, quinones, steroids, monoterpenes, sesquiterpenes, polyphenolics and tannins which are anti-atherosclerotic. This study aims to determine the effect of giving the ethanol fraction of purple sweet potato leaves on rat blood flow and coagulation factors and its effect on the histopathological picture of the rat aorta induced by high-fat sup…
Luka terbuka merupakan luka yang mengakibatkan kerusakan pada kulit jika diabaikan akan terjadi infeksi. Tanaman obat yang telah diteliti dan dimanfaatkan untuk penyembuhan luka terbuka salah satunya yaitu daun kardia (Bellucia pentamera Naudin). Daun kardia (Bellucia pentamera Naudin) mengandung senyawa flavonoid, saponin, tannin, fenolik, dan triterpenoid sebagai antijamur, antivirus, antibak…
Gotu Kola (Centella asiatica L.) and gambier (Uncaria gambir Roxb.) is a plant that is believed to have many benefits. The high antioxidant content, especially flavonoids, triterpenoids, polyphenols, saponins from gotu kola and gambier leaves are believed to improve memory. This study aims to determine the levels of flavonoids, levels of proximate snack bar characteristics , and to determine th…
Rimpang temu mangga (Curcuma amada Roxb.) mengandung metabolit sekunder seperti flavonoid, kurkuminoid dan fenolik yang berpotensi memiliki aktivitas antiulcer. Penelitian ini bertujuan untuk mengetahui efek antiulcer ekstrak etanol rimpang temu mangga (EERTM) yang diinduksi etanol absolut. Efek antiulcer ini dilihat dari parameter seperti, evaluasi lesi lambung, pengukuran volume, pH, keasaman…
Peronema canescens (sungkai leaf) contains flavonoid secondary metabolites that show activity as immunostimulants. This study aims to determine the properties of Orally Dissolving Film (ODF) of sungkai leaf extract, immunomodulatory effects, macroscopic and histopathology of rat spleen. ODF was prepared using solvent casting method. Immunity parameters observed were CD4+ T cell values using PIM…
Ethyl acetate fraction from lakum air (Ludwigia octovalvis (Jacq.) P.H. Raven) fruit has α-glucosidase inhibitory activity as antidiabetic. The results of phytochemical screening from ethyl acetate fraction of lakum air fruit contain flavonoids, saponins, phenolics, and tannins. Based on the useful compounds, we need to know their safety, supported by toxicity testing. In this research, an acu…
The research on the antidiabetic activity of the ethyl acetate fraction from lakum air (Ludwigia octovalvis (Jacq.) P.H. Raven) fruit in streptozotocin-induced male white rats of wistar strain was aimed to determining the decrease in blood glucose levels, ED50 (Effective Dose 50) and the histopathological effect on the pancreas from diabetic rats type 2 treated with the ethyl acetate fraction o…
Background: Wound is a disruption of the continuity of the epithelial lining of the skin or mucosa due to physical or thermal damage. One of the injuries that occur in the soft tissues of the oral cavity is the post-tooth extraction wound. Herbal ingredients that can be used for wound healing are baung fish. The content of omega-3 and albumin in baung fish can be antibacterial, anti-inflammator…
Background: Extraction is a minor oral surgical procedure performed to remove a tooth or tooth root from its socket on the alveolar bone in the oral cavity. The process of tooth extraction causes hard and soft tissue damage. Currently, many studies use bio-based materials, for example those from plants. One type of plant that contains bioactive compounds that can be developed is duku seeds. Bas…
Background: Traumatic ulcer are lesions of the oral mucosa caused by thermal, mechanical and chemical. Long-term use of topical medication can lead resistance to fungal infection. Several studies have shown that patin fish skin contains glycine and glutamic acid which can increase macrophage activation and fibroblast proliferation in the wound healing process that wound healing will be accelera…
Background: Inflammation is the body's initial response to tissue damage caused by trauma, exposure to toxins, or infection.One of the natural ingredients that have anti-inflammatory potential is catfish oil. The purpose of this study was to determine the anti-inflammatory activity of catfish oil gel in affecting the number of neutrophil cells in male white rats of the wistar strain induced by …
Latar Belakang: Daun tanaman karamunting memiliki potensi sebagai alternatif terapi diabetes melitus tipe 2 karena mengandung senyawa bioaktif yang memiliki aktivitas antioksidan dan antinflamasi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian fraksi air daun karamunting (Rhodomyrtus tomentosa) terhadap sekresi insulin pada tikus model diabetes melitus tipe 2 Metode: Penelitian in…
Mosquitoes experience 4 life cycle stages, namely eggs, larvae, pupae, and adult mosquitoes. The physical and chemical conditions of the water were important parameters that affected the growth, survival, and adaptation of mosquito larvae. TWA Punti Kayu had a potential environment and ecosystem for the spread of mosquito-borne, vector-borne diseases. The purpose of this study was to investigat…
Introduction: The use of cinnamon in daily life, either as a cooking ingredient or as herbal therapy, is unknown and there has been no previous research on the efficacy of cinnamon extract as a renoprotector. This studi aims to determine the efficacy of the ethanolic extract of cinnamon bark (Cinnamomum burmannii) whether it can act as a renoprotector in lowering urea levels in the kidney. Meth…
Gentamicin is one example of an aminoglycoside that gives its users nephrotoxic side effects. Although gentamicin has had nephrotoxic effects until now there is still little research on the effects of gentamicin on the kidneys and making gentamicin as an induction drug to make animals try models of renal fibrosis. The purpose of this study was to determine the nephrotoxic effect that leads to r…
Diarrheal disease caused by Escherichia coli bacteria is still common in Indonesia. Kersen plant (Muntingia calabura L.) is widely used to treat various diseases, namely jaundice, gout and cough, but it can also be used as an antipyretic, antioxidant, anti-inflammatory, antidiabetic, antibacterial and antiulcer. Kersen leaves contain active compounds of flavonoids and tannins which act as antib…
Beluntas leaf have antioxidant activity by inhibiting lipid peroxidation thereby preventing the formation of malondialdehyde (MDA). The purpose of this study is to determine the effect on antioxidant activity of n-hexane fraction of beluntas leaves by measuring MDA levels, knowing catalase enzyme activity and macroscopic and histopathological features of CCl4-induced rat liver. The treatments w…
Diuretics are used as drugs to treat hypertension. Diuretics work to remove excess fluid in the body by increasing the process of urine formation. The secondary metabolite content in jackfruit leaves which is thought to have potential as a diuretic is phenolic compounds. This study aims to determine the diuretic activity of the ethyl acetate fraction of jackfruit leaves. Total phenolic content …
Non-mammalian synapsids were the dominant terrestrial vertebrates from the Late Carboniferous to the Middle Triassic and play a key role in understanding the origin and evolution of mammals. Despite these facts and the outstanding fossil record of the group, early synapsids remain obscure. This book showcases the full breadth of contemporary research on non-mammalian synapsids, ranging from tax…
Penelitian mengenai Keanekaragaman Mamalia di Hutan Bukit Asam Tanjung Enim Sumatera Selatan ini bertujuan untuk memperoleh data jenis dan informasi tentang keanekaragaman mamalia yang terdapat di kawasan hutan Bukit Asam. Pengambilan data pada penelitian ini dilaksanakan pada bulan April 2009 hingga Mei 2009, bertempat di hutan Bukit Asam Tanjung Enim, Kecamatan Lawang Kidul Kabupaten Muara En…
Abstract : The Sumatran elephant (Elephas maximus sumatranus) is one of the large mammals owned by Indonesia and is included in the protected endangered species according to the Regulation of the Minister of Environment and Forestry of the Republic of Indonesia No.P.106/MENLHK/SETJRN/KUM.1/6/2018. The Padang Sugihan Wildlife Sanctuary (SM) Elephant Training Center is a conservation area that is…
Antidiabetic activity test of ethanolic extract coffee robusta‟s leaves (Coffea canephora) to rats induced by alloxan has been done. Male wistar albino rats are used as animal models which divided into 6 groups, normal group (aquadest), negative control group (Na CMC 0,5%), positive control group (glibenclamide 0,43 mg/200 gBB), and 3 test group (ethanolic extract of coffee robusta‟s leave …
Background. Kersen parasite leaves (Dendropthoe pentandra L. Miq) is a type of parasite that is hemiparasitic and contains active compounds, namely, flavonoids, terpenoids and tannins. This compound has benefits as an antidiabetic. This study aims to determine the effect of lowering blood glucose levels from the infusion of Kersen parasite leaves (Dendrophthoe pentandra L. Miq) in male rats ind…
Background: Diabetes mellitus is a metabolic disease whose incidence is increasing every year. The use of plants as alternative medicines can be an option because of the affordability of prices and availabilities. The Kersen Benalu plant (Dendrophthoe pentandra (L.) Miq.) is reported to contain the same antidiabetic compounds as its host, the Kersen plant (Mutingia calabura L.). This study aims…