Osteoarthritis (OA) merupakan bentuk penyakit sendi yang paling umum ditemukan di dunia dan diasosiasikan oleh usia. OA bermula saat faktor katabolik, sepeti TNF-α, yang berperan pada metabolisme kartilago mendominasi dan menekan faktor anabolik membuat degradasi kartilago terjadi. Faktor pertumbuhan yang didapat dari platelet memiliki peran krusial dalam penyembuhan jaringan dan respons imun.…
Osteoarthritis (OA) adalah gangguan sendi yang paling umum dan merupakan penyebab utama disabilitas dengan dampak sosial ekonomi yang besar dan terjadi akibat ketidakseimbangan mediator proinflamasi dan antiinflamasi atau aktivitas anabolik dan katabolik. Penelitian ini bertujuan untuk mengetahui pengaruh Faktor Pertumbuhan Platelet (FPP) terhadap kadar Alpha-SMA. Penelitian ini merupakan studi…
Comprehension learners sometimes have a different understanding of concepts than scientifically accepted concepts, leading to misconceptions. The purpose of this study was to determine the validity and reliability of three tier diagnostic tests of human reproductive system material in high school students in Muara Enim Regency. The method in this study is the Treagust development method which i…
Background: Stem of yellow wood (Arcangelisia flava) is a plant that are efficacious as an antihyperuricemic. This is because it contains secondary metabolites in the form of alkaloids, flavonoids, terpenoids, and tannins. Previous research conducted in vitro research on ethyl acetate extract from stem of the yellow wood (Arcangelisia flava) which has been proven to be antihyperuricemic. This s…
Osteoarthritis (OA) adalah penyakit degeneratif tulang rawan sendi yang diikuti oleh peradangan rongga synovial. Interleukin-1β (IL-1β) bertanggung jawab pada proses terjadi OA. Faktor pertumbuhan platelet diprediksi mampu memodulasi penyembuhan OA. Tujuan penelitian ini untuk mengetahui pengaruh pemberian FPP terhadap kadar IL-1β. Eksperimental in vivo menggunakan pendekatan post-test only …
White tea has pharmacological activity as an antidiabetic because it contains polyphenol compounds in the form of epigallocatechin gallate (EGCG) which can inhibit the α-glucosidase enzyme so that blood glucose levels can be returned within normal limits. However, plant extracts have low oral bioavailability, so the formula in the form of SNEDDS (Self-Nano Emulsifying Drug Delivery Systems) is…
Daun beluntas (Pluchea indica L.) mengandung metabolit sekunder seperti flavonoid yang berpotensi sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui karakterisasi, jumlah kadar flavonoid total, dan pengaruh pemberian fraksi etil asetat daun beluntas terhadap kadar MDA, aktivitas enzim katalase, gambaran makroskopik dan histopatologi hepar tikus yang diinduksi CCl4, serta mengeta…
This study aims to determine the Role of Yakesma South Sumatra in Empowering Youth through Humanitarian Activities. This study used a qualitative approach with qualitative descriptive methods, the sampling technique used in this study was a purposive sampling technique with 6 informants and used data collection techniques, namely documentation, interviews and observation techniques. From the re…
Melinjo leaves (Gnetum gnemon L.) have been widely researched in their use as an efficacious medicinal plant. Flavonoid as secondary metabolite compounds contained in melinjo leaves have the potential to be antioxidants. Antioxidant activity test on the ethanol fraction of melinjo leaves was tested with in vivo method with the aim of determining its effect on malondialdehyde (MDA) levels, catal…
This study aims to determine the effect of using the E-LKPD based on the Project Based Learning (PjBL) model on student learning outcomes in the human circulatory system material for class XI SMA with research subject students (n = 76) class XI MIPA SMA Negeri 13 Palembang. The research method used is Quasi Experiment with a Nonequivalent Control Group Design. The research instruments used were…