EVALUASI MIKROANATOMI GINJAL PEMBERIAN SELF NANO EMULSION (SNE) EKSTRAK TEH P…

White tea has pharmacological activity as an antidiabetic because it contains polyphenol compounds in the form of epigallocatechin gallate (EGCG) which can inhibit the α-glucosidase enzyme so that blood glucose levels can be returned within normal limits. However, plant extracts have low oral bioavailability, so the formula in the form of SNEDDS (Self-Nano Emulsifying Drug Delivery Systems) is…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN BELUNTAS (Pluchea indica L.…

Daun beluntas (Pluchea indica L.) mengandung metabolit sekunder seperti flavonoid yang berpotensi sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui karakterisasi, jumlah kadar flavonoid total, dan pengaruh pemberian fraksi etil asetat daun beluntas terhadap kadar MDA, aktivitas enzim katalase, gambaran makroskopik dan histopatologi hepar tikus yang diinduksi CCl4, serta mengeta…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETANOL DAUN MELINJO (Gnetum gnemon L.) TERHA…

Melinjo leaves (Gnetum gnemon L.) have been widely researched in their use as an efficacious medicinal plant. Flavonoid as secondary metabolite compounds contained in melinjo leaves have the potential to be antioxidants. Antioxidant activity test on the ethanol fraction of melinjo leaves was tested with in vivo method with the aim of determining its effect on malondialdehyde (MDA) levels, catal…

Rancangan Percobaan: Teori & Aplikasi, Edisi Ketiga

Buku ini menuntun peneliti dan mahasiswa dalam memahami dan menguasai falsafah dan penerapan ilmu rancangan percobaan dalam penelitiannya.

UJI EFEK GASTROPROTEKTIF EKSTRAK ETANOL RIMPANG TEMULAWAK (Curcuma Xanthorrhi…

Rimpang temulawak mengandung senyawa metabolit sekunder berupa flavonoid, steroid, triterpenoid dan tannin. Penelitian ini bertujuan untuk mengetahui efek gastroprotektif ekstrak etanol rimpang temulawak melalui parameter makroskopik lambung, volume, pH, keasaman total cairan lambung, kadar mucin, serta pengamatan mikroskopik. Tikus dibagi menjadi 6 kelompok yaitu kelompok normal, kontrol posit…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN SALAM (SYZYGIUM POLYANTHUM …

Ketidakseimbangan antara jumlah radikal bebas dan antioksidan endogen tubuh menimbulkan stress oksidatif yang dapat menyebabkan kerusakan sel. Tubuh memerlukan asupan antioksidan dari luar tubuh, baik sintetis atau alami. Salah satu sumber antioksidan alami adalah daun salam yang mengandung flavonoid yang dapat menstabilkan radikal bebas. Pengujian aktivitas antioksidan fraksi etil asetat daun …

PENGARUH PEMBERIAN FRAKSI ETANOL DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN PARA…

Purple sweet potato leaves contain alkaloids, flavonoids, quinones, steroids, monoterpenes, sesquiterpenes, polyphenolics and tannins which are anti-atherosclerotic. This study aims to determine the effect of giving the ethanol fraction of purple sweet potato leaves on rat blood flow and coagulation factors and its effect on the histopathological picture of the rat aorta induced by high-fat sup…

UJI AKTIVITAS EKSTRAK ETANOL DAUN KARDIA (Bellucia pentamera Naudin) TERHADAP…

Luka terbuka merupakan luka yang mengakibatkan kerusakan pada kulit jika diabaikan akan terjadi infeksi. Tanaman obat yang telah diteliti dan dimanfaatkan untuk penyembuhan luka terbuka salah satunya yaitu daun kardia (Bellucia pentamera Naudin). Daun kardia (Bellucia pentamera Naudin) mengandung senyawa flavonoid, saponin, tannin, fenolik, dan triterpenoid sebagai antijamur, antivirus, antibak…

EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINAS…

Gotu Kola (Centella asiatica L.) and gambier (Uncaria gambir Roxb.) is a plant that is believed to have many benefits. The high antioxidant content, especially flavonoids, triterpenoids, polyphenols, saponins from gotu kola and gambier leaves are believed to improve memory. This study aims to determine the levels of flavonoids, levels of proximate snack bar characteristics , and to determine th…

UJI EFEK ANTIULCER EKSTRAK ETANOL RIMPANG TEMU MANGGA (Curcuma amada Roxb.) T…

Rimpang temu mangga (Curcuma amada Roxb.) mengandung metabolit sekunder seperti flavonoid, kurkuminoid dan fenolik yang berpotensi memiliki aktivitas antiulcer. Penelitian ini bertujuan untuk mengetahui efek antiulcer ekstrak etanol rimpang temu mangga (EERTM) yang diinduksi etanol absolut. Efek antiulcer ini dilihat dari parameter seperti, evaluasi lesi lambung, pengukuran volume, pH, keasaman…

PENGARUH PEMBERIAN ORALLY DISSOLVING FILM EKSTRAK DAUN SUNGKAI (Peronema cane…

Peronema canescens (sungkai leaf) contains flavonoid secondary metabolites that show activity as immunostimulants. This study aims to determine the properties of Orally Dissolving Film (ODF) of sungkai leaf extract, immunomodulatory effects, macroscopic and histopathology of rat spleen. ODF was prepared using solvent casting method. Immunity parameters observed were CD4+ T cell values using PIM…

UJI TOKSISITAS AKUT FRAKSI ETIL ASETAT BUAH LAKUM AIR (Ludwigia octovalvis (J…

Ethyl acetate fraction from lakum air (Ludwigia octovalvis (Jacq.) P.H. Raven) fruit has α-glucosidase inhibitory activity as antidiabetic. The results of phytochemical screening from ethyl acetate fraction of lakum air fruit contain flavonoids, saponins, phenolics, and tannins. Based on the useful compounds, we need to know their safety, supported by toxicity testing. In this research, an acu…

UJI AKTIVITAS ANTIDIABETES FRAKSI ETIL ASETAT BUAH LAKUM AIR (Ludwigia octova…

The research on the antidiabetic activity of the ethyl acetate fraction from lakum air (Ludwigia octovalvis (Jacq.) P.H. Raven) fruit in streptozotocin-induced male white rats of wistar strain was aimed to determining the decrease in blood glucose levels, ED50 (Effective Dose 50) and the histopathological effect on the pancreas from diabetic rats type 2 treated with the ethyl acetate fraction o…

PENGARUH EKSTRAK IKAN BAUNG (Hemibagrus nemerus) TERHADAP JUMLAH NEUTROFIL PA…

Background: Wound is a disruption of the continuity of the epithelial lining of the skin or mucosa due to physical or thermal damage. One of the injuries that occur in the soft tissues of the oral cavity is the post-tooth extraction wound. Herbal ingredients that can be used for wound healing are baung fish. The content of omega-3 and albumin in baung fish can be antibacterial, anti-inflammator…

PENGARUH EKSTRAK BIJI DUKU (Lansium domesticum Corr)TERHADAP JUMLAH NEUTROFIL…

Background: Extraction is a minor oral surgical procedure performed to remove a tooth or tooth root from its socket on the alveolar bone in the oral cavity. The process of tooth extraction causes hard and soft tissue damage. Currently, many studies use bio-based materials, for example those from plants. One type of plant that contains bioactive compounds that can be developed is duku seeds. Bas…

PENGARUH GELATIN KULIT IKAN PATIN (PANGASIUS SP) TERHADAP PENINGKATAN JUMLAH …

Background: Traumatic ulcer are lesions of the oral mucosa caused by thermal, mechanical and chemical. Long-term use of topical medication can lead resistance to fungal infection. Several studies have shown that patin fish skin contains glycine and glutamic acid which can increase macrophage activation and fibroblast proliferation in the wound healing process that wound healing will be accelera…

EFEK ANTIINFLAMASI GEL MINYAK IKAN PATIN (Pangasius hypophthalmus) PADA TIKUS…

Background: Inflammation is the body's initial response to tissue damage caused by trauma, exposure to toxins, or infection.One of the natural ingredients that have anti-inflammatory potential is catfish oil. The purpose of this study was to determine the anti-inflammatory activity of catfish oil gel in affecting the number of neutrophil cells in male white rats of the wistar strain induced by …

PENGARUH FRAKSI AIR DAUN KARAMUNTING (RHODOMYRTUS TOMENTOSA) TERHADAP SEKRESI…

Latar Belakang: Daun tanaman karamunting memiliki potensi sebagai alternatif terapi diabetes melitus tipe 2 karena mengandung senyawa bioaktif yang memiliki aktivitas antioksidan dan antinflamasi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian fraksi air daun karamunting (Rhodomyrtus tomentosa) terhadap sekresi insulin pada tikus model diabetes melitus tipe 2 Metode: Penelitian in…

KORELASI KONDISI FISIK DAN KIMIA AIR DENGAN JUMLAH LARVA NYAMUK PADA TEMPAT P…

Mosquitoes experience 4 life cycle stages, namely eggs, larvae, pupae, and adult mosquitoes. The physical and chemical conditions of the water were important parameters that affected the growth, survival, and adaptation of mosquito larvae. TWA Punti Kayu had a potential environment and ecosystem for the spread of mosquito-borne, vector-borne diseases. The purpose of this study was to investigat…

EFEKTIVITAS EKSTRAK ETANOL KULIT KAYU MANIS (Cinnamomum burmannii) TERHADAP P…

Introduction: The use of cinnamon in daily life, either as a cooking ingredient or as herbal therapy, is unknown and there has been no previous research on the efficacy of cinnamon extract as a renoprotector. This studi aims to determine the efficacy of the ethanolic extract of cinnamon bark (Cinnamomum burmannii) whether it can act as a renoprotector in lowering urea levels in the kidney. Meth…

EFEK NEFROTOKSIK GENTAMISIN TERHADAP TIKUS WISTAR.

Gentamicin is one example of an aminoglycoside that gives its users nephrotoxic side effects. Although gentamicin has had nephrotoxic effects until now there is still little research on the effects of gentamicin on the kidneys and making gentamicin as an induction drug to make animals try models of renal fibrosis. The purpose of this study was to determine the nephrotoxic effect that leads to r…

BIOKIMIA : EKSPERIMEN LABORATORIUM

Edition

-

ISBN/ISSN

979-519-082-2

Collation

x, 189 hlm.; ilus.; 24cm

Series Title

-

Call Number

612.015 072 4 Bio b

Pedoman Penggunaan Tikus Sebagai Hewan Uji Laboratorium

Edition

-

ISBN/ISSN

978-623-203-043-5

Collation

x, 119 hlm.; ilus.; 24cm

Series Title

-

Call Number

619 Les p

RANCANGAN PERCOBAAN: Teori & Aplikasi, Edisi Ketiga

Edition

3

ISBN/ISSN

979-421-295-4

Collation

xiv, 260 hlm., 21 cm

Series Title

-

Call Number

519.52 Han r

PENGARUH FRAKSI NONPOLAR KAYU MANIS (CINNAMOMUM BURMANNII) TERHADAP KADAR KOR…

Insomnia is a sleep disorder that reduces the quality of life. Insomnia affects the HPA Axis by increasing cortisol levels. Cinnamomum burmannii is a plant that has antiinflammatory and antioxidant activity. This study aims to determine effect of nonpolar fraction of cinnamon on cortisol levels. This study was an in vivo experimental study using a post-test only design and a control group at th…

PENGARUH PEMBERIAN EKSTRAK TULANG IKAN PATIN TERHADAP ANGIOGENESIS PASCA EKST…

Background: Tooth extraction is a surgical procedure that can cause injury to the socket. Catfish (Pangasius pangasius) is freshwater fish which its bones can be used because it contains such as collagen and arginine. Collagen and arginine has been reported can increase the number of new blood vessels in the wound healing process. Aim: To determine the effect of catfish bone extract on angiogen…

PENGARUH FRAKSI NONPOLAR KAYU MANIS (Cinnamomum burmannii) TERHADAP KADAR GAB…

Background: Insomnia is a sleep disorder that adversely affects health and quality of life. Therapy using GABA-A receptor agonists has a variety of side effects. Cinnamon contains anti-inflammatory and antioxidant compounds. This study aims to determine the effect of cinnamon nonpolar fraction (CNF) on GABA levels. Methods: This study is an experimental study in vivo post-test only with a contr…

PENGARUH FRAKSI NONPOLAR KAYU MANIS (CINNAMOMUM BURMANNII) TERHADAP KADAR SER…

Insomnia is a body disorder characterized by decreased sleep quality in the form of difficulty initiating or maintaining sleep. Insomnia is often associated with serotonergic cell death. Cinnamon (Cinnamomum burmannii) is a plant studied to have anti-inflammatory and antioxidant effects. This study aims to determine the efficacy of the nonpolar fraction of cinnamon on serotonin levels. This stu…

EFEK NEFROTOKSIK ASAM FOLAT TERHADAP TIKUS WISTAR.

There is less scientific research about effect of inducing high doses of folic acid on the kidneys of wistar rats and research on creating animal models of kidney fibrosis. The purpose of this study was to determine the nephrotoxic effect that leads to kidney fibrosis in the induction of high doses of folic acid in wistar rats. In vivo experimental research was carried out in September-October …

 PENGARUH FRAKSI NONPOLAR KAYU MANIS (Cinnamomum burmannii) TERHADAP KADAR M…

Background: Insomnia is a sleep disorder that decreases quality of life and melatonin level due to chronic inflammatory, but the current treatment is still not effective. Cinnamon is rich in anti-inflammatory and antioxidants compounds. This study aims to determine the effect of the cinnamon nonpolar fraction on melatonin levels. Methods: This study is an experimental study in vivo post-test on…