UJI AKTIVITAS DIURETIK EKSTRAK ETANOL DAUN SUNGKAI (Peronema canescens jack.)…

The sungkai leaf (Peronema canescens jack.) is known to contain flavonoid compounds with potential diuretic properties. This study aimed to evaluate the diuretic activity of ethanolic extract from sungkai leaves through preclinical tests on experimental animals divided into six treatment groups. These groups consisted of a normal control (aquadest), a negative control (NaCMC), a positive contro…

UJI ANALGETIKA DAN ANTIINFLAMASI EKSTRAK DAN FRAKSI DAUN KARDIA (Bellucia pen…

The Kardia plant (Bellucia Pentamera Naudin), a member of the Melastomataceae family, contains compounds such as steroids, triterpenoids, and flavonoids, which exhibit potential analgesic and anti-inflammatory properties. This study aims to characterize the extract and evaluate its analgesic and anti-inflammatory effects based on the reduction in writhing behavior in mice and edema volume in ra…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK BERGRADIEN EMPAT TANAMAN OBAT ANTIHIPERTENS…

Free radical that can cause damage to body cells by oxidative stress as a trigger factor for degenerative diseases with the presence of antioxidant compounds able to counteract free radical. Medical plants ciplukan, guajava, katuk, and cat’s whiskers are utilized as antihypertensive traditional medicine because their bioactive compounds support blood pressure control. This study was conducted…

OPTIMASI FORMULASI NANOPARTIKEL EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L…

Moringa leaf (Moringa oleifera L.) are proven to contain secondary metabolites, one of which is flavonoids in the form of quercetin which has the ability as an anticancer. This study aims to determine the optimum formula of nanoparticles from a variety of alginate chitosan coatings at concentrations of 0.3% and 0.6% conjugated with folic acid. Moringa leaf extract was obtained through maceratio…

UJI AKTIVITAS PENYEMBUHAN LUKA BAKAR SUBMIKRO EMULSI EKSTRAK DAUN SAMBILOTO D…

Andrographis paniculata (Burm.f.) Nees) contains andrografolid, a compound that has anti-inflammatory, antibacterial, and antioxidant activities to accelerate burn wound healing. This study evaluated the preparation of submicro emulsion of bitter melon leaf extract with Tween 20 and PEG-400 at a concentration of 10% and tested the burn wound healing activity in Wistar rats. This study was divid…

OPTIMASI FORMULASI NANOPARTIKEL EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth.)…

Kenikir leaves (Cosmos caudatus Kunth.) contain flavonoid group compound quercetin which has potential as anti-cancer. The extract of kenikir leaves has low solubility and bioavailability so that a modification of the drug delivery system is needed in the form of folic acid-conjugated chitosan-alginate polymer-based nanoparticles. Folic acid-conjugated chitosan carries the drug to folate recept…

PREPARASI DAN UJI AKTIVITAS ANTI NEFROLITHIASIS NANOSUSPENSI FRAKSI DAUN MELI…

Gnetum gnemon leaves contained flavonoids that had the potential to dissolve kidney stones by increasing urinary citrate excretion and diuresis. The low bioavailability of fractions required nanoparticle dosage forms as an option to increase the effectiveness of the delivery system. This study aimed to determine the percentage of nanosuspension entrapment efficiency used for in vivo tests and t…

POTENSI ANTIINFLAMASI EKSTRAK ETANOL HERBAL SAMBILOTO (ANDROGHAPIS PANICULATA)

Inflammation is the body's protective mechanism against tissue damage caused by physical trauma, chemical irritation, or microbial infection. However, the use of synthetic anti-inflammatory drugs, such as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), often leads to side effects, including gastrointestinal irritation and impaired kidney function. Sambiloto (Andrographis paniculata) is an herba…

UJI TOKSISITAS AKUT FRAKSI ETIL ASETAT DAUN GAMAL (Gliricidia sepium) TERHADA…

Gamal leaves (Gliricidia sepium) have pharmacological activity as anthelmitic, hepatoprotector and antibacterial. The content of secondary metabolites in the ethyl acetate fraction of gamal leaves are flavonoids, tannins and saponins. The purpose of this study was to determine the effects of acute toxicity of the ethyl acetate fraction of gamal leaves with testing parameters of biochemical leve…

PREPARASI DAN UJI AKTIVITAS ANTINEFROLITIASIS NANOSUSPENSI FRAKSI ETIL ASETAT…

Kidney stones (nephrolithiasis) were a common health problem in Indonesia. The kersen leaf (Muntingia calabura L.) contained flavonoid compounds that acted as diuretics. The use of nanosuspension preparations was chosen to enhance the effectiveness and bioavailability of the fraction in delivering the active substance to the target. The aim of this study was to determine the %EE and characteriz…

PREPARASI DAN UJI ANTINEFROLITIASIS FRAKSI ETANOL DAUN KERSEN (Muntingia cala…

Daun kersen (Muntingia calabura L.) diketahui memiliki efek farmakologi sebagai antinefrolitiasis karena mengandung senyawa flavonoid yang dapat berikatan dengan kalsium pada batu ginjal dan meningkatkan ekskresi urin. Senyawa bahan alam mempunyai kelarutan dan bioavailabilitas yang rendah dalam air sehingga dapat diatasi dengan inovasi sediaan berupa nanosuspensi. Penelitian ini bertujuan untu…

KRATOM: Kajian Botani, Fitokimia, Farmakologi, Isolasi, dan Analisis

Edition

-

ISBN/ISSN

978-623-02-2723-3

Collation

x, 101 hlm.; 20 cm

Series Title

-

Call Number

582.12 Fir k

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN ALPUKAT (PERSEA AMERICANA), DAUN JAMBU…

Long-term exposure to excess free radicals in the body can cause oxidative stress and various diseases, so antioxidant compounds are needed to neutralize free radicals. This research was conducted to determine the strongest antioxidant activity of avocado leaves, water guava leaves and cherry leaves which have been used empirically by the Ogan Ilir community. The extract with the strongest anti…

DOMESTIKASI BUAH MERAH

Edition

-

ISBN/ISSN

978-602-440-864-0

Collation

82 hlm. : ill. ; 23 cm.

Series Title

-

Call Number

634.6 Dar d

OPTIMASI FORMULA NANOSTRUCTURED LIPID CARRIER EKSTRAK KULIT JERUK MANIS (Citr…

The utilization of sweet orange peel is still minimal as it is often overlooked after fruit processing for consumption, despite being rich in bioactive compounds, including flavonoids, especially for topical preparations. Previous research has mainly focused on conventional formulations with limitations in skin penetration. The Nanostructured Lipid Carrier (NLC) delivery system can enhance perc…

AKTIVITAS ANTIOKSIDAN SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT DAUN…

Excessive free radicals in the body can cause oxidative stress conditions which result in tissue damage. This condition can be prevented by consuming antioxidants. Cherry leaves (Muntigia calabura L.) often used as a medicinal plant and are believed to have antioxidant properties. Based on previous research, methanol extract of cherry leaves has strong antioxidant activity, while the ethyl acet…

PEMISAHAN FRAKSI KOLOM DARI FRAKSI ETIL ASETAT DAUN KERSEN (MUNTINGIA CALABUR…

Kersen leaves (Muntingia calabura L.) have been proven to have antioxidant properties, both in the form of crude extracts and fractions. The ethyl acetate fraction of kersen leaves separated by vacuum liquid column chromatography has strong antioxidant activity (IC50 43,40 µg/mL). This research is a continuation of the previous research by further separating the fraction of vacuum liquid colum…

EVALUASI AKTIVITAS ANTIOKSIDAN DAN ANTIINFLAMASI FRAKSI DAUN SUKUN (Artocarpu…

Plants that contain high levels of flavonoid and phenol compounds have the potential to act as antioxidants and anti-inflammatories. One of them is the breadfruit plant (Artocarpus altilis). This study aims to determine the antioxidant and anti-inflammatory activity of breadfruit leaf fractions. The research began with extraction by maceration using solvents with varying polarities (n-hexane, e…

PEMISAHAN SENYAWA METABOLIT DARI FRAKSI n-HEKSANA KAYU BATANG MURBEI PUTIH (M…

Separation of metabolite compounds from the n-hexane fraction of the wood of the M. alba L. plant has not been widely carried out. TLC analysis showed that M. alba L. has many metabolite compounds. This research was aimed to determine metabolite compounds from the n-hexane fraction of the wood of the M. alba L. plant using the gas chromatography-mass spectrometry (GC-MS) method. The extraction …

SOLASI SENYAWA METABOLIT SEKUNDER TURUNAN FENOLIK DARI FRAKSI ETIL ASETAT BAT…

Morus alba L. is a plant from Moraceae family which is found in tropical and subtropical areas. M. alba plant was reported to have displayed several bioactivities such as antioxidant, antitumor, antibacterial, anticancer, antidiabetic, and anti-inflammatory. M. alba plant has a diversity of secondary metabolites. This research was aimed to isolate and identify secondary metabolite compounds fro…

UJI POTENSI IMUNOMODULATOR PADA MENCIT (MUS MUSCULUS) DAN ANTI PROLIFERASI SA…

Sungkai (Peronema canescens Jack.) is one of woody plants which is usually found in the Southern part of Sumatra which is often used as an herbal plant by people for flu and fever. This research was aimed to know immunomodulator potency of Sungkai in mice (Mus muculus) and effect extract to proliferation of Saccharomyces cerevisiae yeast and leukocytes. Yeast proliferation is associated with in…

Atlas Tumbuhan Obat Indonesia Jilid II

Edition

-

ISBN/ISSN

979-661-065-5

Collation

xii, 214 hal. : ilus. ; 24 cm

Series Title

-

Call Number

633.88 Dal a

TAKSONOMI TUMBUHAN OBAT-OBATAN

Edition

1

ISBN/ISSN

979-420-300-9

Collation

ix., 457 hlm.; ill.; 21 cm

Series Title

-

Call Number

581.634 Tji t

AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 80 DAN…

Bitter leaf extract (Andrographis paniculate (Burm.f) Wall. Ex Ness) contains secondary metabolites andrographolide and quercetin which have potential antibacterial activity. This research aims to determine the nanoemulsion formulation with a combination of Tween 80 and Ethanol 96% concentration on the activity of Propionibacterium acnes and the stability of ICH Q1A (R2). Data analysis in this …

AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 20 DAN…

Sambiloto leaves (Andrographis paniculate (Burm. F) Wall ex. Ness) contain andrografolid and flavonoids as the main compounds that have potential as antibacterial. Nanoemulsion with a combination of tween 20 and PEG-400 was carried out to produce preparations that have better antibacterial effects and are thermodynamically stable. This study was conducted to determine the characteristics and st…

STUDI IN SILICO POTENSI SENYAWA DAUN OREGANO (Origanum vulgare L.) SEBAGAI AG…

Tuberculosis is a contagious respiratory tract infection caused by Mycobacterium tuberculosis. This research utilized an in silico approach to predict the molecular potential of target compounds in oregano leaves (Origanum vulgare L.) for antituberculosis activity. The potential compounds in oregano leaves included phytol, carvacrol, γ-terpinene, p-cymene, and cyclotetradecane. The SwissADME d…

OPTIMASI KONSENTRASI TWEEN 80 DAN ETANOL 96% DALAM SEDIAAN NANOEMULSI EKSTRAK…

Ekstrak daun sukun (Artocarpus altilis (Parkinson) Fosberg) mengandung senyawa metabolit sekunder utama flavonoid dan fenolik. Penelitian ini bertujuan untuk mengetahui optimum konsentrasi Tween 80 dan Etanol 96% dalam sediaan nanoemulsi ekstrak etanol daun sukun. Optimasi dilakukan dengan desain faktorial 22 menggunakan Design Expert 12®. Formula optimum yang diperoleh selanjutnya dilakukan k…

OPTIMASI PATCH TRANSDERMAL EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) TER…

Wounds or damage to part of the body tissue if not treated immediately will cause infection and even death. Plants that can help the wound healing process include alpha mangostin compounds from mangosteen skin (Garcinia mangostana L.). Optimization of active substance delivery is carried out in the form of transdermal patch preparations. This study aims to obtain the optimum formula for transde…

PREPARASI DAN KARAKTERISASI TRANSDERMAL PATCH EKSTRAK KULIT MANGGIS (Garcinia…

Mangosteen peel extract has an alfa-mangosteen compound that can accelerate cell healing by stimulating fibroblast growth, thus providing effects as an anti�inflammatory and antimicrobial. The choice of transdermal patch dosage form for mangosteen peel extract aims to effectively deliver active substances through the skin to reach the systemic. The purpose of this study was to obtain a formul…

OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI ETOSOM FRAKSI ETIL ASETAT EKSTRAK DAUN…

Daun singkong (Manihot Esculenta Crantz.) mengandung senyawa metabolit yang dihasilkan salah satunya flavonoid terdapat rutin dikenal sebagai quercetin-3-rutinoside yang berpotensi sebagai anti acne. Etosom memiliki kemampuan sebagai pengantar untuk meningkatkan transfer bahan aktif melalui kulit dengan lebih efisien dalam hal permeabilitas kulit. Tujuan dari penelitian ini adalah mengetahui fo…