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KORELASI KADAR BRAIN DERIVED NEUROTROPHIC FACTOR DAN FUNGSI KOGNITIF PADA PAS…
ABSTRACT THE CORRELATION OF BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) AND COGNITIVE FUNCTION IN ELDERLY PATIENTS AT THE GERIATRIC OUTPATIENT CLINIC OF RSMH PALEMBANG Devin Fidela, Yuniza, Nur Riviati, Iche A. Liberty Department of Internal Medicine, Faculty of Medicine, Sriwijaya University Dr. Mohammad Hoesin Hospital Palembang Background: Cognitive impairment represents a major public health c…
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- xi, 29 hlm.; ilus.; tab.; 29 cm.
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- T1938092026
PENGARUH PEMBERIAN SUPLEMEN VITAMIN D TERHADAP KADAR BRAIN DERIVED NEUROTROPH…
Background: Aging is often accompanied by cognitive decline, where Mild Cognitive Impairment (MCI) serves as a transitional phase at risk of developing into dementia. The pathophysiology of this condition is closely related to neurobiological mechanisms, including low levels of Brain-Derived Neurotrophic Factor (BDNF) and the high prevalence of Vitamin D insufficiency in the elderly population.…
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- xviii, 178 hlm.; ilus.; tab.; 29 cm.
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- T1940572026
PENGARUH PEMBERIAN EVOO TERHADAP MASSA OTOT, KEKUATAN OTOT, STATUS PERFORMA D…
Pendahuluan: Proses penuaan menyebabkan penurunan massa otot, kekuatan otot, dan performa fisik (sarkopenia), yang dipengaruhi oleh inflamasi kronik tingkat rendah dengan peningkatan kadar interleukin-6 (IL-6). Extra Virgin Olive Oil (EVOO) mengandung polifenol seperti hydroxytyrosol dan oleuropein yang bersifat antioksidan dan antiinflamasi, berpotensi memperbaiki fungsi otot pada lansia. Tuju…
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- xiv, 75 hlm.; ilus.; 29 cm
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- T1885702025
FAKTOR-FAKTOR YANG MEMENGARUHI GANGGUAN TIDUR PADA REMAJA PELAJAR SMP DI PALE…
Latar Belakang: Gangguan tidur pada remaja secara global cukup besar, sekitar 25-30%. Sementara itu gangguan pada proses tidur dapat menimbulkan masalah serius pada kesehatan fisik dan perilaku pada remaja. Tujuan: Mengidentifikasi faktor-faktor yang memengaruhi gangguan tidur pada remaja SMP di Palembang. Metode: Penelitian ini merupakan observasional analitik dengan desain potong lintang pada…
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- xiv, 87 hlm.; ilus.; 29 cm
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- T1921782025
HUBUNGAN RASIO NEUTROFIL-LIMFOSIT, RASIO PLATELET-LIMFOSIT, DAN INDEKS INFLAM…
Penelitian ini dilakukan di Sungai Napalan, Desa Umpam, Kecamatan Lengkiti, Kabupaten Ogan Komering Ulu, Sumatera Selatan, yang bertujuan untuk menganalisis karakteristik mikrofosil foraminifera pada batugamping Formasi Baturaja bagian bawah, tengah, dan atas. Metode penelitian meliputi studi pendahuluan, observasi lapangan, analisis laboratorium, serta interpretasi data di studio. Dari 15 loka…
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- xvi, 138 hlm.; ilus.; tab.; 29 cm.
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- T1939412026
SELF-ASSESSMENT KESEHATAN MENTAL PADA DOKTER GIGI MUDA DI RUMAH SAKIT KHUSUS …
ABSTRAK Latar Belakang: Dokter gigi muda rentan mengalami gangguan kesehatan mental, seperti depresi, kecemasan, dan stres akibat tingginya tekanan akademik maupun klinis yang mereka hadapi. Tujuan: Menganalisis kesehatan mental dokter gigi muda di Rumah Sakit Khusus Gigi dan Mulut Provinsi Sumatera Selatan serta faktor-faktor yang memengaruhinya. Metode: Penelitian ini menggunakan desain mixed…
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- v, 50 hlm.; ilus.; tab.; 29 cm.
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- T1937972026
Sintesis, karakterisasi, dan kajian respon sel terhadap hidrogel injeksi kito…
Nekrosis pulpa pada gigi permanen muda menyebabkan terhentinya perkembangan akar sehingga gigi rentan mengalami fraktur. Perawatan yang bertujuan meregenerasi kompleks dentin-pulpa pada gigi permanen muda yang mengalami nekrosis adalah prosedur endodontik regeneratif. Kitosan telah digunakan sebagai scaffold pada prosedur tersebut, akan tetapi potensi regeneratifnya belum cukup optimal. Fucoida…
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- xvii, 194 hlm.; ilus.; tab.; 29 cm.
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- T1921662025
NYERI PADA PERAWATAN ORTODONTI DENGAN CLEAR ALIGNER DAN ORTODONTI CEKAT (Syst…
Background: Orthodontic treatment using clear aligners or fixed appliances often causes pain in patients. This pain may affect comfort and compliance during orthodontic therapy. Objective: This study aims to determine whether there is a difference in pain intensity among malocclusion patients undergoing treatment with clear aligners compared to fixed orthodontic appliances. Methods: This resear…
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- xiv, 165 hlm.; ilus.; 29 cm
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- T1919132025
KORELASI ANTARA KADAR VITAMIN D DENGAN RASIO NEUTROFIL LIMFOSIT (RNL) PADA PA…
Latar Belakang: Vitamin D berperan penting sebagai pelindung dalam patogenesis sepsis dengan cara meredam inflamasi neutrofil dan menjaga fungsi limfosit. Rendahnya kadar vitamin D berkontribusi langsung pada buruknya profil hematologi (seperti tingginya RNL) dan peningkatan risiko gagal organ pada pasien sepsis. Penelitian ini bertujuan untuk mengetahui korelasi antara kadar vitamin D dengan r…
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- xv, 120 hlm.; ilus.; tab.; 29 cm.
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- T1928442025
PERBANDINGAN EFEK FENTANYL DAN SUFENTANIL TERHADAP RESPONS HEMODINAMIK SAAT L…
Introduction: Laryngoscopy and endotracheal intubation may provoke sympathetic activation, resulting in increased blood pressure and heart rate, particularly in hypertensive patients. Opioids such as fentanyl and sufentanil are commonly used to attenuate this hemodynamic response. However, comparative evidence regarding their effects in hypertensive patients remains limited. Methods: This doubl…
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- xvi, 187 hlm.; ilus.; tab.; 29 cm.
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PERBANDINGAN SURVIVAL RATE PASIEN ANAPLASTIC LARGE CELL LYMPHOMA SUBTIPE ALK-…
Background. Anaplastic Large Cell Lymphoma (ALCL) is a mature T-cell lymphoma characterized by strong CD30 expression and is classified into ALK-positive and ALK-negative subtypes. Although both subtypes share similar histopathological features, differences in ALK expression are associated with distinct biological behavior, treatment response, and prognosis. International studies have reported …
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- xv, 42 hlm.; ilus.; 29 cm
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- T1918882026
HUBUNGAN KADAR VITAMIN D 25(OH) DENGAN INFEKSI LATEN TUBERKULOSIS PADA PASIEN…
Pendahuluan: Pasien penyakit ginjal kronik (PGK) yang menjalani hemodialisis kronik memiliki risiko tinggi mengalami infeksi laten tuberkulosis (ILTB) akibat kondisi imunokompromais. Defisiensi vitamin D diketahui berperan dalam penurunan respons imun terhadap Mycobacterium tuberculosis. Namun, hubungan antara kadar vitamin D 25(OH) dengan kejadian ILTB pada populasi hemodialisis di Indonesia m…
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- xx, 59 hlm.; ilus.; 29 cm
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- T1907652025
EFEKTIVITAS TEKNIK ATP DALAM MENINGKATKAN OHI-S ANAK TUNANETRA DI SEKOLAH DAS…
Blind children are a group of children who have limited vision or are totally blind. Blind children have obstacles in communication, limited learning media, and lack of teaching resources. A survey from the World Health Organization (WHO) shows that blind children under 15 years of age have worse dental and oral health than normal children. This is because blind children have difficulty detecti…
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- x, 68 hlm.; ilus.; tab.; 29 cm.
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- T1925402026
PENGARUH PEMBERIAN ESTRADIOL TERHADAP EKSPRESI BIOMARKER NEKROPTOSIS DAN PERA…
Introduction: Sepsis is a leading cause of morbidity and mortality in critically ill patients. While estradiol administration shows potential as a sepsis therapy, its impact on the necroptosis process remains unclear. This study aims to investigate the effect of estradiol administration on necroptosis and inflammation in a sepsis-induced Wistar rat model. Methods: This experimental study employ…
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- xviii, 295 hlm.; ilus.; tab.; 29 cm.
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- T1894192025
FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUASAN PELAYANAN KESEHATAN PASIEN RAWAT INA…
Health is a basic need that supports people’s daily activities and productivity. Hospitals, as referral health care facilities, are required to provide high-quality services in line with the implementation of the National Health Insurance (JKN) program through BPJS Kesehatan. Various problems such as limited health personnel, service time, attitudes of medical staff, and the quality of facili…
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- xix, 118 hlm.; ilus.; tab.; 29 cm.
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- T1926772026
HUBUNGAN ANTARA KADAR hs-CRP SERUM DENGAN KEJADIAN INFEKSI LATEN TUBERKULOSIS…
Latar Belakang: Pasien penyakit ginjal kronik (PGK) yang menjalani hemodialisis memiliki risiko lebih tinggi mengalami infeksi laten tuberkulosis (ILTB) akibat disfungsi imun dan kondisi inflamasi kronis. High-sensitivity C-reactive protein (hsCRP) merupakan penanda inflamasi yang sering meningkat pada populasi ini, namun hubungannya dengan kejadian ILTB masih belum jelas terutama di Indonesia.…
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- vii, 64 hlm.; ilus.; 29 cm
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- T1910652025
PENGARUH PEMBERIAN EXTRA VIRGIN OLIVE OIL TERHADAP KADAR COX-2, MASSA OTOT, K…
Latar Belakang : Penuaan menyebabkan penurunan massa otot, kekuatan otot, dan performa fisik akibat proses inflamasi kronik derajat rendah yang ditandai peningkatan enzim COX-2 dan ROS. EVOO mengandung senyawa fenolik seperti oleocanthal dan hydroxytyrosol yang bersifat antioksidan dan antiinflamasi melalui inhibisi jalur NF-κB–COX-2, sehingga berpotensi menekan inflamasi dan mempertahankan …
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- xvii, 86 hlm.; ilus.; 29 cm
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- T1893402025
KORELASI KADAR VITAMIN D SERUM DENGAN KETEBALAN KARTILAGO HIALIN PADA PASIEN …
Latar Belakang: Osteoartritis (OA) lutut merupakan salah satu penyakit sendi degeneratif yang ditandai dengan penipisan kartilago hialin dan inflamasi kronik. Vitamin D memiliki peran penting dalam metabolisme tulang, modulasi respon imun, dan aktivitas kondrosit. Penurunan kadar vitamin D serum diduga berhubungan dengan penurunan ketebalan kartilago hialin. OA menjadi masalah global karena dap…
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- vii, 64 hlm.; ilus.; 29 cm
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- T1900472025
IMPLEMENTASI KEBIJAKAN EKONOMI PEMERINTAH TERHADAP HIMPUNAN PENGUSAHA MUDA SU…
This research aims to analyze the implementation of government economic policies regarding the South Sumatra Indonesian Young Entrepreneurs Association (HIPMI) in an effort to develop Micro, Small, and Medium Enterprises (MSMEs) in Palembang City. Utilizing the implementation model by Van Meter and Van Horn, this study evaluates six key dimensions: policy standards and objectives, resources, ch…
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- vii, 64 hlm.; ilus.; 29 cm
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- T1921882025
KORELASI EKSPRESI CLAUDIN 18.2 DENGAN SUBTIPE HISTOPATOLOGI ADENOKARSINOMA LA…
Background: Gastric adenocarcinoma remains a global health burden with high mortality, while effective targeted therapies are still limited. Claudin-18.2 is a transmembrane tight-junction protein selectively expressed in normal gastric mucosa and retained in gastric adenocarcinoma. Its role as a novel therapeutic target, including zolbetuximab, highlights the importance of investigating claudin…
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- xviii, 70 hlm.; ilus.; tab.; 29 cm.
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- T1899382025
HUBUNGAN REKURENSI STOMATITIS AFTOSA REKUREN TERHADAP POLA MAKAN PADA MAHASIS…
Latar Belakang: Stomatitis Aftosa Rekuren (SAR) merupakan sariawan berulang tanpa penyakit sistemik yang dapat mengganggu kualitas hidup, terutama pada mahasiswa. Salah satu faktor predisposisinya adalah pola makan yang tidak seimbang yang dapat menyebabkan defisiensi nutrisi dan menurunkan imunitas. Tujuan: “Mengetahui hubungan antara rekurensi SAR dengan jenis, jumlah, dan frekuensi pola ma…
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- xiv, 85 hlm.; ilus.; tab.; 29 cm.
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- T1923272026
IDENTIFIKASI POLA KEPEKAAN BAKTERI Klebsiella pneumoniae DARI SPESIMEN SPUTUM…
Klebsiella pneumoniae is a Gram-negative bacterium that can cause various infectious diseases, including pneumonia. Throughout its history, this bacterium has developed resistance to antibiotics. K. pneumoniae exhibits various resistance strategies, including enzymatic modification, gene mutations, and increased efflux pumps. The increasing prevalence of resistance each year has become a key fa…
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- xv, 54 hlm.; ius.; 29 cm
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- T1632032024
PENGARUH EKSTRAK ETIL ASETAT DAUN UBI JALAR UNGU (Ipomoea batatas L.) TERHADA…
Free radicals are molecules with unpaired electrons that can cause tissue damage through oxidative stress, accelerate aging, and trigger various diseases, including cancer. Antioxidants play an important role in warding off free radicals. Purple sweet potato leaves (Ipomoea batatas L.) are known to contain active compounds such as polyphenols, flavonoids, tannins and triterpenoids which have hi…
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- xvii, 78 hlm.; ilus.; 29 cm
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- T1629822024
EVALUASI KEBERHASILAN PERAWATAN ORTODONTI CEKAT PADA KASUS PENCABUTAN PREMOLAR
Background: Malocclusion is commonly encountered conditions, with the global prevalence reaching 56% and up to 80% in Indonesia. One of the most frequent types of malocclusion is dental crowding. Moderate to severe dental crowding often requires premolar extraction to provide adequate space during fixed orthodontic treatment. Premolar extraction is a widely used strategy to improve dental align…
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- vii, 67 hlm.; ilus.; 29 cm
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- T1909442025
PENGARUH BERKUMUR LARUTAN GAMBIR TERHADAP LAJU ALIR SALIVA PADA KONDISI XEROS…
Xerostomia was closely associated with hyposalivation, which had negative impacts on oral health and led to a decreased quality of life in patients; therefore, it was necessary to increase the salivary flow rate. Gambir contained catechins and tannins, which were reported to be able to increase salivary flow rate.Objective: To determine the effect of gargling gambir solution on salivary flow ra…
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- xv, 73 hlm.; ilus.; 29 cm
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- T1910532025
PEMANFAATAN KOLAGEN IKAN PATIN (Pangasius sp.) DALAM PROSES REGENERASI TULANG…
Background: Tooth extraction is the most frequently performed treatment in dentistry, with a rate reaching 7.9%. The impact of tooth extraction is alveolar bone resorption, so alternative treatments are needed that can accelerate alveolar bone regeneration with natural ingredients, namely catfish collagen. Objective: To determine the benefits and effects of administering catfish collagen on the…
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- xiii, 36 hlm.; ilus.; 29 cm
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- T1910492025
HUBUNGAN ANTARA PEMERIKSAAN RADIOLOGIS DAN PIRANI SCORE PADA PASIEN CONGENITA…
ASSOCIATION BETWEEN RADIOLOGICAL EXAMINATION AND PIRANI SCORE IN PATIENTS WITH CONGENITAL TALIPES EQUINOVARUS (CTEV) WITH PONSETTI METHOD MANAGEMENT AT DR. MOHAMMAD HOESIN GENERAL HOSPITAL PALEMBANG Abstraìct Baìckground: Clinicaìl feaìtures of deformity haìve been claìssified by Piraìni, so thaìt its severity caìn be aìssessed aìt birth aìnd the progress of treaìtment caìn be mon…
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- xviii, 295 hlm.; ilus.; tab.; 29 cm.
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- T1900682025
AKTIVITAS ANTIBAKTERI PERMEN JELI BUAH NANAS (Ananas comosus) DAN STEVIA TERH…
Porphyromonas gingivalis is the main anaerobic bacterium responsible for gingivitis and periodontitis. The use of natural ingredients such as pineapple (Ananas comosus) and stevia has potential as antibacterial agents capable of inhibiting and even killing Porphyromonas gingivalis, and can be developed into products in the form of jelly candy. This study aimed to determine the antibacterial act…
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- xiv, 58 hlm.; ilus.; 29 cm
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- T1910002025
UJI DIAGNOSTIK ALAT PEMERIKSAAN CEPAT LATERAL FLOW IMMUNOCHROMATOGRAPHIC ASSA…
Background: Vulvovaginal candidiasis (VVC) is a very common mucosal infection in the vagina and vulva, mostly caused by Candida albicans. Accurate diagnosis requires supportive examinations such as direct microscopic evaluation or fungal culture; however, in practice, these ancillary tests are often omitted in women presenting with vulvovaginal symptoms due to high patient burden and the need f…
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- xxvi, 67 hlm.; ilus.; 29 cm
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- T1913782025
EFIKASI PEMBERIAN LARUTAN DEKSTROSA 25% ORAL UNTUK MENGATASI NYERI PADA TINDA…
Procedural pain is a common clinical issue in neonates, particularly during venipuncture. Inadequately managed pain can trigger physiological stress, hemodynamic instability, and may negatively affect long-term neurodevelopment. Non-pharmacological analgesic strategies such as oral dextrose have become a practical option due to their simplicity, safety, and ability to reduce reliance on pharmac…
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- xv, 74 hlm.; ilus.; 29 cm
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- T1899122025
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