Backgrounds: Head injury is one of the leading causes of morbidity and mortality in trauma cases and remains a major public health concern worldwide. In Indonesia, head injuries most commonly occur as a result of traffic accidents, particularly among productive age groups. Profiling head injury patients is essential for evaluating healthcare services, management strategies, and prevention progr…
Background: Hirschsprung disease (HSCR) is a congenital intestinal disorder caused by aganglionosis that requires histopathological confirmation; a full-thickness biopsy (FTB) is sometimes used to establish the diagnosis and determine definitive management. Methods: This retrospective descriptive-analytic study used medical records from Dr. Mohammad Hoesin General Hospital Palembang (January 20…
Backgrounds: Impetigo is a common superficial skin infection often caused by Streptococcus pyogenes. Mupirocin is a first-line treatment, but rising antibiotic resistance encourages the search for alternative therapies, including pineapple core (Ananas comosus L. Merr) extract, which contains active compounds such as bromelain with potential antibacterial effects. This study aimed to evaluate t…
Thalassemia is a genetic blood disorder that requires lifelong management, including regular blood transfusions and iron chelation therapy. This condition affects the quality of life of children, which is strongly influenced by their parents’ level of knowledge in providing care. This study aimed to determine the relationship between parents’ level of knowledge and the quality of life of ch…
Introduction: Sepsis is a life-threatening organ dysfunction, one of the leading cause of morbidity and mortality worldwide, including Indonesia. The rapid progression of the disease and its variable clinical manifestations affect sepsis- related mortality. Biomarker testing, particularly plasma lactate level, plays a vital role as an indicator of tissue hypoxia, a predictor of mortality, and a…
Uremic pruritus is one of the most common complications in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD) and can significantly reduce quality of life. The severity of pruritus is influenced by several factors, including the duration of HD. However, to date, there are no available data describing the relationship between hemodialysis duration and the severity of uremic …
Background: Nutrition remains a major health problem in Indonesia, including stunting rates among toddlers. According to the 2023 Indonesian Child Health Survey (SKI), the prevalence of stunting in Indonesia is 21.5%, with South Sumatra reaching 20.3% and Palembang City at 18.9%, including 0.3% at the Sako Community Health Center (Puskesmas), which is still far from the 2024 RPJMN target of red…
Background: Allergic rhinitis is one of the most common atopic diseases in children, characterized by inflammation of the nasal mucosa due to type I hypersensitivity reactions mediated by immunoglobulin E (IgE), often caused by house dust mites. Methods: This study is an observational analytical study with a cross-sectional approach using medical records and laboratory data on pediatric allergi…
Soil-Transmitted Helminth (STH) infections remain a public health problem in Indonesia, with a prevalence of 28.12%. STH infections can lead to growth retardation in children and decreased work productivity in adults. Transmission occurs through the fecal–oral route, and consumption of contaminated vegetables can serve as a medium for infection. The development of hydroponic farming systems, …
Antibiotic resistance in the NICU continues to be a global problem, increasing neonatal mortality and morbidity rates. Excessive broad-spectrum empiric antibiotic therapy increases the DOT (Days of Therapy) per 1000 patient-days metric and promotes resistance development through selective pressure. The high antibiotic usage in the NICU prompted research on the effect of DOT per 1000 patient-day…
Breast cancer is the most common type of cancer in the world. Chemotherapy can be one of the treatment options and has been proven to have a significant impact on patient survival. However, there are concerns about the side effects of chemotherapy that can affect the cognitive function of patients, known as chemotherapy-induced cognitive impairment (CICI). This study aims to determine the cogni…
Freezing of gait (FOG) is a symptom characterized by a sudden inability to step during walking, described as feet feeling glued to the floor, particularly when initiating gait, turning, or facing obstacles. This symptom commonly accompanies parkinsonism and potentially increases fall risk and decreases quality of life. This study aimed to describe the characteristics of FOG in parkinsonism pati…
Chemotherapy is the main treatment for breast cancer; however, it may cause cognitive impairment, known as chemobrain, which is characterized by a decline in memory, attention, reasoning, concentration, processing speed, executive function, and visual ability. Clinicopathological factors such as age, education, marital status, cancer stage, type and number of chemotherapy cycles are believed to…
Background: The presence of Students with Special Needs (PDBK) in schools creates complex psychological dynamics for other students. The responses that emerge are reflected in regular students’ knowledge, attitudes, and behaviors toward PDBK. Methods: This study used a descriptive quantitative design with a survey approach involving 100 twelfth-grade regular students at SMAN 2 Palembang. Data…
Coronary Slow-Flow Phenomenon (CSFP) is characterized by delayed coronary blood flow without significant stenosis, with a prevalence of 1–7% and 38.3% at Dr. Mohammad Hoesin General Hospital Palembang. The condition often causes recurrent chest pain and increases cardiovascular risk. Endothelial dysfunction is suspected to play a role in its pathogenesis, while dyslipidemia may contribute thr…
Background: Lung carcinoma is the most common carcinoma and the leading cause of cancer-related death, particularly among men. The disease may be primary or metastatic and is classified into Non-Small Cell Lung Carcinoma (NSCLC) and Small Cell Lung Carcinoma (SCLC). The main risk factor is smoking, followed by exposure to pollution, radiation, genetic factors, and advanced age. Chest X-ray play…
Cholelithiasis is the formation of gallstones due to an imbalance between cholesterol, bile salts, and phospholipids. Factors such as age, gender, and body mass index (BMI) play important roles in this process. Older age is associated with decreased activity of the enzyme 7α-hydroxylase, which reduces bile acid production, while higher estrogen levels in females increase cholesterol secretion …
Polycystic Ovary Syndrome (PCOS) is an endocrine disorder characterized by an imbalance of LH and FSH hormones, insulin resistance, and dyslipidemia, which increase the risk of metabolic complications. Purple sweet potato (Ipomoea batatas L. Poir) is known to contain anthocyanins and flavonoids with antioxidant properties that contribute to improving lipid profiles. This study aims to evaluate …
Acute coronary syndrome (ACS) is one of the leading causes of cardiovascular morbidity and mortality worldwide, including in Indonesia. This condition occurs due to the sudden obstruction of coronary blood flow caused by rupture or erosion of atherosclerotic plaques. Platelet activation plays a role in the process of atherothrombosis and the formation of coronary thrombi. Platelet indices such …
Background: Musculoskeletal pain is one of the most common occupational health problems experienced by healthcare workers, particularly dentists. In Indonesia, the prevalence of musculoskeletal disorders among dentists reaches 58.9%, indicating that this condition is a significant issue requiring proper attention. Various risk factors contribute to this condition, including working posture, str…
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Urinary tract infection (UTI) is one of the most common complications associated with diabetes mellitus. This study aims to determine whether there is an association between patient characteristics specifically sex, age, and body mass index (BMI), and the incidence of urinary tract infection (UTI) in patients with…
Background. DSD is a heterogeneous group of congenital conditions associated with variations in chromosomes, gonads, or anatomical sex. CAH is classified as a DSD that is usually diagnosed based on ambiguous genitalia in newborn girls or salt-wasting crises. Early diagnosis and treatment of CAH DSD patients is crucial. However, a major challenge is that research conducted primarily at the natio…
Background: Neck pain is one of the most common musculoskeletal complaints among adolescents, particularly those who spend extend periods sitting and maintaining non-ergonomic neck positions during academic activities. Neck position can be assessed using the Craniovertebral Angle (CVA), which biomechanically correlates with increased load on the cervical muscles. However, evidence regarding the…
Background: The spine is the central supporting structure of the body. Adolescent Idiopathic Scoliosis (AIS) is a three-dimensional structural deformity of the spine that occurs in adolescents 10-17 years old which is characterized by lateral curvature in the frontal plane, thoracic lordosis in the sagittal plane, and rotation of the vertebrae in the transverse plane, with a Cobb angle reaching…
Background: Anemia in pregnancy is a common maternal health problem contributing to prematurity, morbidity, and maternal–infant mortality. Low hemoglobin leads to placental hypoxia, HPA-axis activation, and increased prostaglandins that trigger early uterine contractions. This study analyzed the association between anemia and prematurity at RSUP Dr. Mohammad Hoesin Palembang. Methods: This an…
Background: Candy is a processed food in the form of a solid and if consumed excessively it will reduce the salivary pH which is one of the factors causing caries. This decrease occurs due to the activity of acid-producing bacteria in the oral cavity. Preventing a decrease in salivary pH can be done by adding gambir and xylitol to candy. Gambir is a herbal ingredient containing catechins and ta…
Background: The liver is susceptible to damage due to exposure to free radicals, which trigger oxidative stress. This condition increases AST and ALT enzymes, which are markers of liver injury. This study used CCl₄-induced Wistar rats as a model of liver damage. Antioxidants are needed to prevent damage, and silymarin was used as a positive control. Purple sweet potato leaf extract contains f…
Background. Endometrial carcinoma is a gynecological malignancy originating from the endometrial lining of the uterus. It ranks as the sixth most common cancer among women worldwide, and its incidence is associated with excessive estrogen exposure to the endometrium. This study aims to describe the risk profile and therapeutic modalities of patients with endometrial carcinoma treated at RSUP Dr…
Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a wide spectrum of clinical manifestations, ranging from mild cutaneous abnormalities to severe organ dysfunction. Previous studies have shown a decrease in lymphocyte count, or lymphopenia, in SLE patients, which is often associated with disease activity. However, research on the relationship betwee…
Background: Hypospadias is the second most common congenital anomaly found in males after cryptorchidism, with urethrocutaneous fistula being the most frequent postoperative complication. The incidence rate of urethrocutaneous fistula is one of the indication of the success of hypospadias management. The age at surgery is suspected to play a role in determining the treatment outcome. However, r…