Rice (Oryza sativa) is the primary crop that produces rice and plays an important role in supporting Indonesia’s economy. One of the major diseases that frequently infects rice plants is blast disease, which is caused by the fungus Pyricularia oryzae. As a more environmentally friendly alternative, the use of microorganisms as biological agents can inhibit and suppress pathogen development su…
ABSTRACT Ceratocystis wilt, which attacks duku plants (Lansium domesticum), has become one of the main factors contributing to the decline in duku production in South Sumatra in recent years. The pathogen Ceratocystis fimbriata is known to be aggressive, easily spread, and difficult to control using conventional methods, thus requiring more environmentally friendly control strategies, one of wh…
Anak dengan hemofilia memiliki risiko tinggi mengalami artropati sendi akibat perdarahan berulang. Penelitian ini bertujuan untuk mengidentifikasi faktor risiko yang berhubungan dengan artropati tahap lanjut pada pasien anak dengan hemofilia. Penelitian observasional analitik dengan desain potong lintang dilakukan di RS Mohammad Hoesin Palembang pada Januari hingga Juni 2025. Sebanyak 42 anak d…
Ceratocystis fimbriata is an important pathogen in duku (Lansium domesticum Corr.) plants that causes stem cancer, tissue rot, and rapid plant death, thereby significantly impacting duku production in South Sumatra. This study aims to evaluate the effectiveness of phosphite acid (K₃PO₃) in inducing duku resistance through in vitro and in vivo testing. The study was conducted using a complet…
Rice blast disease is an important disease caused by the fungus P. oryzae, which can lead to significant yield losses. An alternative control method that can be used to control the attack of the pathogenic fungus is by using plant extracts. One type of plant that has a high ability to suppress the rate of blast development is using turmeric rhizome extract. Therefore, this research was conducte…
In some countries, corn has a carbohydrate content equivalent to rice and wheat, but its production has often declined due to leaf blight disease, which is caused by Helminthosporium sp., resulting in yield losses of up to 50%. This study aims to determine the effect of organic fertilizer application on the level of leaf blight disease (Helminthosporium sp.) on corn plants in the field in Tanju…
Background: The presence of a malignant pleural effusion (MPE) indicates advanced stage in malignancy, which severely compromises in a poor prognosis. The LENT score has been developed as a prognostic tool for MPE, yet its association with pleural effusion progression and six-month survival has not been thoroughly evaluated, particularly in Indonesia. Methods: This prospective cohort study incl…
Background: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia resulting from impaired insulin secretion or insulin resistance, with chronic low-grade inflammation playing a role in its pathogenesis. Diacerein has anti-inflammatory effects and improves insulin sensitivity; however, clinical evidence in Indonesia remains limited. Objective: To evaluate the effect of adding diacere…
Medical data related to chronic liver disease often contain missing values that can reduce the quality of data analysis and the accuracy of predictive models. Handling missing values properly is essential to ensure optimal classification performance. This study aims to apply and evaluate the K-Nearest Neighbor (KNN) Imputation method to address missing values in a medical dataset of liver cirrh…
Background: Acute Coronary Syndrome (ACS) is one of the leading causes of mortality and hospitalization due to cardiovascular disease. Variations in patient characteristics and the presence of metabolic risk factors may influence the occurrence and prognosis of ACS. Therefore, understanding the profile of ACS patient characteristics is essential as a basis for preventive planning and clinical s…
Background: STEMI is an acute condition caused by obstruction of blood flow to the heart, leading to cardiomyocyte necrosis. This process begins with the formation of atherosclerotic plaques that cause total occlusion of the coronary artery lumen, resulting in myocardial ischemia. When transmural ischemia lasts for 20–40 minutes, cardiomyocyte necrosis occurs. Methods: This study aimed to des…
This study discusses the classification of asthma disease using Machine Learning algorithms to address three research questions: the application of Machine Learning in asthma classification, the effect of different dataset conditions, and the algorithm that produces the best performance. The asthma dataset obtained from Kaggle was processed under three scenarios: original, undersampling, and Sy…
Latar belakang: Angular Cheilitis merupakan suatu keadaan inflamasi akut atau kronik yang dapat terjadi di sekitar sudut mulut dan meluas ke kulit ditandai adanya kemerahan, retakan, rasa nyeri, dan tanda lainnya. Keadaan ini lebih sering terjadi pada anak – anak terutama pada anak panti asuhan yang disebabkan oleh berbagai faktor penyebab seperti defisiensi nutrisi terutama pada kondisi keku…
Background. Low back pain (LBP) is one of the most common musculoskeletal complaints and can adversely affect physical function, quality of life, and patient productivity. Vitamin D deficiency, assessed through serum 25-hydroxyvitamin D (25-OH D) levels, plays a role in pain modulation, muscle function, and inflammatory responses, and is suspected to be associated with LBP occurrence. This stud…
Background: Bone marrow trephine biopsy is an essential diagnostic procedure for hematological diseases through assessment of morphology, fibrosis, cellularity, and tumor involvement. Since 2023, Dr. Mohammad Hoesin General Hospital Palembang has routinely performed bone marrow biopsies; however, clinicohistopathological data remain limited. This study aimed to describe the bone marrow clinicoh…
Acute Kidney Injury (AKI) is a clinical syndrome of sudden decrease in glomerular filtration rate. Several risk factors for pediatric GgGA include sociodemographics, congenital diseases, and renal replacement therapy (RRT). GgGA is often found in hospitalized sick children and is at high risk of death. This study used analytic research with a cross sectional approach. Subjects were taken using …
Background. Overcrowded, humid, and unhygienic prison environments increase the risk of skin diseases among inmates. Epidemiological data on skin diseases in Indonesian prisons are still limited; therefore, this study aims to describe the pattern of skin diseases among inmates at the Class IIA Women’s Penitentiary in Palembang. Methods. This study was an analytical observational study with a …
Background: Solid tumors are a major cause of morbidity and mortality in children. The outcomes of pediatric patients with solid tumors are influenced by various factors, including demographic characteristics, nutritional status, perinatal history, socioeconomic conditions, tumor stage, and the type of therapy administered. Data regarding outcomes and associated factors among children with soli…
Background. Neurofeedback therapy is a non-pharmacological approach that trains patients to regulate their brain activity through an EEG-based feedback system. This method has been applied to support neurological recovery in conditions such as stroke, epilepsy, and sleep disorders. However, its clinical implementation in Indonesia remains limited. This study aimed to describe the characteristic…
Background. Chronic cervicitis is a condition characterized by inflammation of the cervix lasting for more than three months and is frequently found in women of reproductive age. This condition can be caused by microbial infections, trauma, or other non-infectious factors. This study aims to describe the clinical cytopathological characteristics of patients with chronic cervicitis at RSUP Dr. M…
Background. Tension-Type Headache (TTH) is one of the most common primary headaches among young adults, especially medical students who are often exposed to intense academic pressure and long hours of gadget use. Digital devices play an important role in daily learning activities, yet prolonged screen time may contribute to physical complaints, including TTH. This study aimed to explore whether…
Background: Retinoblastoma is the most common intraocular malignancy in children and remains associated with high mortality in developing countries due to delayed diagnosis and limited access to care. Epidemiological data in Indonesia, especially in Palembang, are limited. This study aimed to describe the prevalence and characteristics of retinoblastoma patients at Mohammad Hoesin General Hospi…
Introduction. Temporary pacemaker (TPM) is used to manage severe bradycardia, defined as a heart rate
Background: Management of drug-resistant tuberculosis (DR-TB) has improved with the introduction of shorter regimens following the approval of bedaquiline in 2012. Despite its benefits, bedaquiline carries a black box warning due to its potential to prolong the QT interval, raising concerns about cardiotoxicity. This study aimed to evaluate changes in QTcF, determine the prevalence of QT prolon…
Computer Vision Syndrome (CVS) is a collection of symptoms related to prolonged use of digital devices, such as eye strain, dry eyes, and visual disturbances. CVS is a common health issue, especially among university students who frequently use computers for academic activities. This study aims to determine the incidence and risk factors of CVS among students of the Faculty of Medicine, Sriwija…
Pendahuluan: ST-elevation myocardial infarction (STEMI) merupakan bentuk tersering sindrom koroner akut dengan risiko morbiditas dan mortalitas yang tinggi. Lama rawat inap menjadi salah satu indikator prognosis. Penelitian ini bertujuan untuk membandingkan akurasi skor risiko GRACE dan klasifikasi Killip dalam memprediksi lama rawat inap pada pasien STEMI di RS Mohammad Hoesin Palembang. Metod…
Latar Belakang: Penyakit ginjal kronik (PGK) merupakan masalah kesehatan dengan beban morbiditas dan mortalitas yang tinggi, terutama pada pasien dengan faktor risiko seperti hipertensi dan diabetes melitus. Pada stadium lanjut, penurunan fungsi ginjal yang progresif sering memerlukan terapi pengganti ginjal berupa hemodialisis. Pemetaan karakteristik pasien hemodialisis diperlukan sebagai dasa…
Background: Acinetobacter baumannii is an opportunistic pathogen that frequently causes nosocomial infections, especially in patients treated in the intensive care unit (ICU). This bacterium is known for its resistance to many types of antibiotics and has shown a rising trend in infection rates over the past few years. Methods: This study is a retrospective descriptive research that utilizes me…
Background. Acute Lymphoblastic Leukemia (ALL) is the most common hematologic malignancy in children, characterized by abnormal lymphoblastic. Prognosis and treatment evaluation are generally performed through invasive bone marrow examination as gold standard. Therefore, non-invasive hematological parameters are needed to predict prognosis. Platelet involved in bone marrow activation and hemost…
Background: Nasopharyngeal non-Hodgkin lymphoma (NHL) is an extranodal lymphoid malignancy of the head and neck that is treated with systemic chemotherapy. Chemotherapy may be accompanied by changes in hematological parameters; therefore, monitoring of hematological profiles is required. Data regarding the hematological profile of patients with nasopharyngeal NHL in Indonesia are still limited.…