Background. Contractures are one of the serious complications and the major cause of morbidity in patients after burn injury. Contractures lead to loss or reduction in the Range of Motion (ROM) of the joints, interfering with mobility and resulting in difficulty performing daily activities. This study aimed to determine the characteristics of post-burn contracture patients at Dr. Mohammad Hoesi…
Background. Badan Pusat Statistik (BPS) recorded that in 2020-2022, 8.35% of women of reproductive age in Indonesia used IUD Cu T-380A as their contraception choice, making it the fourth most commonly used contraceptive method in Indonesia. Acceptors of IUD T-380A experiencing increased risk of vaginal ecosystem imbalance, or known as bacterial vaginosis. This study aims to determine the relati…
Background: Urinary tract infection (UTI) is a bacterial infection that affects the human urinary system. Bacteria live in the urethra and colonize in the bladder, when urinating the bacteria will come out so that it does not have a negative impact on the body. A significant bacterial count of more than 100,000 cfu/ml is known as bacteriuria. Bacteriuria can be asymptomatic or symptomatic if th…
Infections caused by antibiotic-resistant bacteria, particularly carbapenem-resistant Pseudomonas aeruginosa (CRPA), have become a significant global health issue. Pseudomonas aeruginosa is a common nosocomial pathogen that often demonstrates resistance to many antibiotics. Given the rising cases of antibiotic resistance, alternative treatments are needed, one of which involves utilizing the po…
Background. Streptozotocin (STZ) is a diabetogenic compound used to induce diabetes mellitus (DM) in animal models. A dose of 45–65 mg/kgBW of STZ triggers the destruction of pancreatic beta cells, resulting in a more stable hyperglycemic condition. Hyperglycemia, as a common feature of DM, leads to metabolic disturbances that cause oxidative stress and dyslipidemia. STZ at a dose of 60 mg/kg…
Background: Schizophrenia is a serious psychiatric disorder characterized by impairments in thought processes, perception, and emotional responses significantly impacting social functioning. Evaluating social functioning is essential for determining the severity of symptoms and predicting outcomes in schizophrenia patients. This study aims to describe the social functioning of patients with sch…
Acute lymphoblastic leukemia (ALL) is a hematological malignancy that frequently occurs in children, with a peak incidence between 2–5 years of age. Treatment for ALL often involves chemotherapy using anticancer drugs to destroy cancer cells. One commonly used drug class is anthracyclines, which are known for their cardiotoxic effects. Anthracycline-induced cardiotoxicity can damage the heart…
PDA, or Patent Ductus Arteriosus, is a condition where the ductus arteriosus remains open. PDA is the most common acyanotic congenital heart disease at Mohammad Hoesin Palembang Hospital. Treatment options for PDA include medication, transcatheter procedures, or ligation. This study is conducted to identify the sociodemographic and clinical characteristics of PDA patients who underwent treatmen…
Diffuse large B cell lymphoma (DLBCL) is a subtype of non-Hodgkin lymphoma (NHL) characterized by large B lymphoid cells, where the nucleus exceeds the size of a normal lymphocyte nucleus, exhibiting a spectrum of cellular progenitors and consistent nuclear morphology. Platelets and lymphocytes are commonly assessed to predict the prognosis of DLBCL patients. The platelet-to-lymphocyte ratio (P…
Osteoporosis is a disease characterized by increased bone fragility and an elevated risk of fractures. Bisphosphonates, which can inhibit bone resorption and increase BMD, are the first choice for the pharmacological management of osteoporosis. One of the bisphosphonates given by injection is zoledronic acid. Side effects that may arise from administering zoledronic acid include decreased calci…
Background: Critically ill patients are patients who are at high risk of serious and life-threatening health problems. Critically ill patients undergo treatment in the Intensive Care Unit (ICU) and are often indicated for early fluid resuscitation to improve hemodynamic stability and tissue perfusion, and reduce ICU mortality. Positive fluid balance is associated with higher mortality than nega…
Children with Down syndrome face various challenges that affect their quality of life, such as developmental delays and congenital comorbidities. The role of parents, particularly their motivation in supporting their child's therapy, is crucial to improving their child's well-being. This study aims to analyze the relationship between parental motivation and the quality of life of children with …
Background : Caesarean section delivery has been significantly rising over the past two decades, including in Indonesia, where the rate has reached 17.6%, surpassing the World Health Organization's recommended range (10-15%), and is even higher in certain regions such as Jakarta. This increase raises concerns as C-section performed without clear medical indications may lead to serious complicat…
Background: Cutaneous Adnexal Tumors (CATs) are neoplasms arising from the differentiation of adnexal skin structures, including sebaceous glands, hair follicles, apocrine, and eccrine glands. While most CATs are benign, some have malignant potential. Major risk factors include genetic predisposition, ultraviolet radiation, and ionizing radiation. The scarcity of research data in Palembang and …
Osteoporosis merupakan penyakit sistemik yang ditandai oleh penurunan densitas tulang (BMD) dan kerusakan mikroarsitektur tulang, yang meningkatkan risiko fraktur. Terapi bisfosfonat, termasuk ibandronat dan zoledronat, merupakan salah satu terapi untuk meningkatkan BMD dan mengurangi insidensi fraktur. Penelitian ini bertujuan membandingkan nilai BMD sebelum dan setelah terapi bisfosfonat pada…
Salbutamol is a bronchodilator commonly used in the management of asthma, both in acute and chronic cases. As part of the Short-Acting Beta-2 Agonist (SABA) class, salbutamol is effective in relieving bronchospasms. The purpose of this study was to determine the rationality of drug use at the Merdeka Community Health Center Palembang. A drug utilization study was conducted at Puskesmas Merdeka …
Tumor paru merupakan suatu keganasan yang timbul pada jaringan paru. Tumor terbagi menjadi dua jenis, yaitu tumor jinak (benign tumor) dan tumor ganas (malignant tumor) atau lebih umum disebut sel kanker. Di Indonesia, kanker paru termasuk dalam 5 besar kasus terbanyak yang terjadi pada wanita. Torakotomi merupakan salah satu metode tindakan untuk mendiagnosis dan menatalaksana pasien kanker pa…
Osteoporosis is a systemic bone disease characterized by reduced bone mass density and damage to bone microarchitecture that causes bone fragility and an increased risk of fractures. Therapies that can be applied to people with osteoporosis are, pharmacological and non-pharmacological therapies. The latest pharmacological therapies approved by the FDA (Food and Drug Administration) in the treat…
Nasopharyngeal carcinoma (KNF) is a malignant tumor that originates from the crypts and epithelium or mucosa located in the nasopharynx. This growth usually occurs on the lateral wall of the nasopharynx, especially the Rosenmuller fossa. The purpose of this study was to determine the clinical profile of patients with nasopharyngeal carcinoma in the ENT-KL Department of Dr. Mohammad Hoesin Hospi…
Background: Pediatric thalassemia major require lifelong blood transfusions to compensate inadequate erythrocyte. However, regular blood transfusions cause iron overload. In addition, pathologically in thalassemia, there is also iron accumulation due to faster hemolysis and ineffective erythropoiesis process. Iron overload is toxic for organ so that it must be removed using iron chelation, one …
Background: Infections in the intensive care unit (ICU) are one of the biggest challenges in healthcare, especially due to increasing antibiotic resistance. Understanding antibiogram and antibiotic sensitivity is very important to determine effective therapeutic strategies and prevent further resistance. This study aims to determine the antibiogram and antibiotic resistance of patients in the I…
Backgrounds: Escherichia coli is a bacteria that often causes serious infections, such as digestive tract, urinary tract and bloodstream infections. One of the main obstacles in its treatment is the ability of these bacteria to form biofilms, which increase resistance to antibiotics and protect against external influences. Uncontrolled use of antibiotics further exacerbates the problem of resis…
Thalassemia is a genetic disorder caused by defects in the production of one or more globin subunits of hemoglobin. In thalassemia major, patients are prone to hemolysis and require regular blood transfusions. Hemolysis and routine blood transfusions can lead to iron accumulation in the body, resulting in elevated ferritin levels, the main iron storage protein. High ferritin levels indicate exc…
Background: Incorrect use of facial skincare products can cause acne in adolescents (juvenile acne). The purpose of this study was to analyze the relationship between the usage of facial skincare and the incidence of juvenile acne. Methods: This cross-sectional analytical observational study was conducted in July - September 2024. Respondents were students of SMA Negeri 1 Palembang and Indralay…
Sepsis is a life-threatening condition that occurs when the body’s immune system fails to respond properly to an infection, leading to organ dysfunction. It remains a significant global health issue, particularly in low- and middle-income countries. This study aimed to examine the distribution of bacterial types and their antibiotic sensitivity patterns in blood cultures from sepsis patients.…
Benign Prostatic Hyperplasia (BPH) is an enlargement of the prostate gland, which is commonly accompanied by the presence of inflammation known as prostatitis on histologic examination. The pattern of prostatitis can be evaluated based on the location, extent, and degree of inflammation. This study aims to provide an overview of the comprehensive evaluation of prostatitis and the clinical profi…
Background: Pathological fracture is a fracture that occurs due to minimal or even normal stress and is the most common and serious complication of osteoporosis. It is important to perform an examination to assess the risk of fractures in individuals who are vulnerable. This study aims to determine the correlation between FRAX score and Bone Mineral Density score in pathologic neck femur fractu…
Oropharyngeal dysphagia is a swallowing disorder commonly observed in geriatric patients due to physiological decline or underlying diseases. FEES (Fiberoptic Endoscopic Evaluation of Swallowing) is performed to evaluate swallowing function and its interaction with the airway. This study aims to determine the characteristics of FEES examination results in geriatric patients with oropharyngeal d…
Kanker ovarium, khususnya subtipe serous, merupakan penyebab kematian utama kanker ginekologi pada perempuan. Keterlambatan diagnosis dan pengobatan yang kurang efektif merupakan salah satu penyebab tingginya angka kejadian dan mortalitas. Faktor risiko yang dapat dimodifikasi seperti indeks massa tubuh (IMT) dan paritas diyakini memiliki potensi pencegahan terhadap karsinoma ovarium subtipe se…
Entropion is a condition in which the edge of the eyelid turns inward, and often leads to the wrong position of the eyelashes. This condition can cause problems such as corneal infections, corneal injuries, the formation of abnormal tissue on the surface of the eye, and even loss of vision. One study states that the incidence of entropion increases with age. Indonesia has one of the largest eld…