Latar Belakang: Forward head posture (FHP) merupakan kelainan postural yang makin sering dijumpai pada remaja akibat penggunaan gawai yang berkepanjangan dan kebiasaan postur yang buruk. Posisi kepala yang terlalu maju dari garis tengah tubuh dapat menyebabkan gangguan otot dan tulang leher serta memengaruhi kualitas hidup di masa depan. Metode: Penelitian ini adalah studi deskriptif observasio…
Background: The high prevalence of oral health problems in Indonesia, especially among children, is due to a lack of knowledge about the importance of maintaining dental health. This study aims to determine the effect of daily book challenge educational media on increasing dental health knowledge of TK Fathul Ilmi students. The method used is a quantitative approach with a quasi-experimental re…
Background: Porphyromonas gingivalis was a pathogenic bacterium that played a role in the development of periodontal diseases, such as periodontitis. Effective treatment to inhibit the growth of this bacterium was highly needed. Chitosan, a biopolymer extracted from the shell of the mud crab (Scylla serrata), was known to have potential antibacterial properties. Objective: The aim of the study …
ABSTRAK Efektivitas Bone Marrow Mesenchymal Stem Cell dan/atau Dienogest Terhadap Ekspresi IL-1β, IL-8 dan Luas Lesi pada Mencit Model Endometriosis Latar Belakang: Endometriosis adalah penyakit inflamasi yang menyebabkan nyeri panggul, dismenore, dan infertilitas. Dienogest adalah terapi standar saat ini namun memiliki banyak efek samping, sehingga diperlukan terapi alternatif yang lebih efek…
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune or inflammatory disease that causes significant damage, occurs because the immune system attacks its own tissues, causing inflammation of the blood vessels. Abnormalities with the loss of the ability to distinguish between foreign substances and one's own tissues and biological responses in urine and blood can help diagnose SLE. Me…
Glaukoma merupakan penyebab utama kebutaan kedua terbesar di seluruh dunia setelah katarak. Glaukoma primer sudut terbuka adalah jenis glaukoma yang ditandai dengan perkembangan atrofi diskus optikus yang lambat, hilangnya lapang pandang perifer, dan diskus optikus yang terekskavasi secara khas. Terdapat 67 juta penduduk di dunia yang menderita penyakit ini. Penelitian ini bertujuan untuk menge…
Background: Chronic renal failure is a disorder of kidney function that is permanent or irreversible. This condition occurs when the body fails to maintain metabolic processes and fluid and electrolyte balance, which can eventually lead to uremia. Globally, the prevalence of chronic renal failure is estimated at 10% of the total population. Methods: This analytical study of correlation design w…
Background: Mutations in the rpoB gene, which encodes the β-RNA-polymerase subunit, occur in an 81-bp area called the Rifampicin Resistant Determining Region (RRDR) in codons 507 to 533. This point mutation area is used to rapidly identify rifampicin-resistant isolates. Mutations in the rpoB gene area in MTb, in addition to having changes in phenotypic properties that cause resistance to the m…
Background: Hepatocelluler carcinoma (HCC) is a malignant tumor originating from hepatocytes and is the most common primary liver tumor. In determining the stage of HCC, it is essensial to assess the size and number of tumor lesions, liver function, physical performance, tumor invasion, extrahepatic metastasis, and clinical symptoms. Several biomarkers such as neutrophil lymphocyte ratio (NLR),…
Latar Belakang: Ulkus kornea adalah luka terbuka pada kornea yang dapat menyebabkan kebutaan jika tidak ditangani dengan baik. Kondisi ini menjadi salah satu penyebab utama kebutaan di negara berkembang, termasuk Indonesia. Selama pandemi Covid-19, manifestasi klinis SARS-CoV-2 pada mata, termasuk konjungtivis, memunculkan pertanyaan mengenai pengaruh pandemi terhadap insiden ulkus kornea. Pene…
Background: Patients at high risk of caries or those who have developed early carious lesions require appropriate and immediate treatment. Untreated carious lesions can lead to extensive tooth structure damage and require invasive procedures. Prevention and management of carious lesions on the occlusal surface can be achieved by applying pit and fissure sealants, one of which is a resin-based f…
Background: Dental caries in children could cause various complications, such as gingival inflammation, abscess formation, malnutrition, periodontal disease, and loss of permanent teeth. Data from the Palembang City Health Office (2018) showed that 53.96% of children aged 5–9 years experienced dental caries. An effective educational method was required to increase children's awareness of main…
Background: Flowable composite resins were low-viscosity and cavity-adaptive restorative materials, making them suitable for minimally invasive restorations. Conventional flowable composite resins formed micromechanical bonds through an adhesive system and had no anticariogenic ability. The addition of fluoride to flowable composite resins provided anticariogenic properties that helped prevent …
Background: Midfacial fractures is one of the most commonly maxillofacial fractures. Fractures site are located on midface complex structure such as os nasal, os palate, os zygomatic, os maxilla, and os maxilla alveolar that has important function in facial aesthetics, respiratory and masticatory system. Pwpose: To determine the prevalence of midfacial fractures at RSUP Dr.Mohammad Hoesin perio…
Latar Belakang: Gigi kaninus maksila permanen berada di urutan kedua paling sering terjadi impaksi setelah gigi molar ketiga. Impaksi gigi kaninus di maksila terjadi sebesar 10-20 kali lebih sering daripada di mandibula. Prevalensi impaksi gigi kaninus maksila cukup tinggi, dan penyesuaian kembali impaksi gigi kaninus ke dalam lengkung gigi telah rutin dilakukan dalam praktik ortodontik. Impaks…
Background: Organizational stress can have a major impact not only on employees but also on organizations. Prolonged stress can develop into burnout, which is a phenomenon that has increased over the past two to three decades. Burnout is a condition of continuous stress with high intensity that makes a person experience physical, mental, and emotional exhaustion. To prevent and reduce the risk …
Latar belakang: C. albicans merupakan flora normal pada manusia, yang biasanya ditemukan di rongga mulut, saluran cerna, vagina, dan kulit. Populasi C. albicans ditemukan di rongga mulut manusia sekitar 35%-80%. Sehingga diperlukan perawatan dan pengobatan dengan menggunakan obat antijamur yaitu nystatin. Namun, penggunaan dari obat antijamur nystatin dapat memberikan efek samping. Tulang ikan …
Latar belakang: Data RISKESDAS 2018 menyatakan bahwa anak usia 10-14 tahun yang memiliki masalah gigi dan mulut mengalami peningkatan sebanyak 55,6%. Salah satu penyebab permasalahan gigi dan mulut ini adalah adanya akumulasi plak pada gigi. Permasalahan ini seringkali terjadi pada anak karena kurangnya pengetahuan dan kesadaran tentang pemeliharaan kesehatan gigi. Oleh karena itu, diperlukan a…
Background: Chewing on one side is one of the bad habit that are still practiced by society. The impact of this habit is plaque buildup, TMJ disorders, mandibular deflection and deviation, and asymmetry of the mastication muscles. Severe asymmetry can interfere with facial aesthetics. Purpose: This study aimed to determine the effect of the habit of chewing on one side of the lips on asymmetry …
Background: Heat polymerized acrylic resin is the most commonly used denture base material. Surface hardness is an important mechanical property of acrylic resin to resist abrasion of the denture base during routine cleaning procedures. Celery leaf juice with a concentration of 50% is effective as a denture cleanser. The ideal denture cleaning solution has bactericidal and fungicidal properties…
Latar Belakang: Perilaku seks bebas diakibatkan kurangnya pengetahuan tentang dampak yang terjadi akibat perilaku seks menyimpang. Kurangnya perhatian dari orang tua, pergaulan bebas, masalah ekonomi, dan faktor lingkungan juga merupakan penyebab masih banyaknya perilaku seksual pranikah pada remaja di Indonesia. Penelitian ini bertujuan untuk menganalisis hubungan antara pengetahuan dan sikap …
Latar Belakang: Perdarahan postpartum (PPH) merupakan salah satu komplikasi obstetri utama yang memberikan kontribusi signifikan terhadap kematian ibu terutama yang disebabkan oleh trombin. Asam traneksamat (TXA) menghambat kapasitas plasminogen dan plasmin untuk berikatan dengan fibrin, sehingga mempertahankan bekuan darah dari lisis yang dimediasi plasmin. Penelitian ini bertujuan untuk menge…
Latar belakang: Pada endometriosis, akumulasi eritrosit yang mengalami lisis dapat memicu kenaikan kadar zat besi (iron overload), yang dapat meningkatkan senyawa gugus hidroksi radikal berdasarkan reaksi Fenton. Produk dari inflamasi kronik dan radikal bebas yang terakumulasi akan menyebabkan dismenore melalui stimulasi nosiseptif antara senyawa tersebut dengan ujung-ujung serabut saraf termin…
Background: There are serious concerns regarding the sexual function of patients undergoing hysterectomy in the postoperative period. 85% of patients who undergo hysterectomy are sexually active, making the effects of hysterectomy on sexual life highly important and not to be overlooked. This study aims to determine the relationship between vaginal length and sexual satisfaction in post-hystere…
Enterococcus faecalis is one of the dominant opportunistic bacteria often associated with etiological factors in human diseases, particularly in the oral cavity. The prevention of microorganism proliferation is essential to address failures in root canal treatments caused by Enterococcus faecalis. Beetroot (Beta vulgaris L.) is known to contain antibacterial compounds such as flavonoids, which …
Background: Candida albicans is a normal microorganism in the oral cavity that can transform into a pathogen caused various infections like oral candidiasis. Nystatin therapy in the long term has the potential to cause side effects. Garlic skin is a natural ingredient that contains active compounds, such as flavonoids, alkaloids, polyphenols, saponins, and quinones that can inhibit fungal growt…
Penelitian ini bertujuan untuk mengkaji secara komprehensif dinamika curah hujan esktrem di bawah pengaruh anomali iklim untuk wilayah Kalimantan dan hubungannya dengan Fenomena Indian Ocean Dipole (IOD) dan El Nin ̃o Southern Oscillation (ENSO). Wilayah Kalimantan yang akan dikaji adalah Kalimantan Barat, Tengah dan Selatan. Analisis Iklim Ekstrem (curah hujan dan temperatur ekstrem) pada pen…