Background: Acute Coronary Syndrome (ACS) is one of the leading causes of mortality and hospitalization due to cardiovascular disease. Variations in patient characteristics and the presence of metabolic risk factors may influence the occurrence and prognosis of ACS. Therefore, understanding the profile of ACS patient characteristics is essential as a basis for preventive planning and clinical s…
Background: STEMI is an acute condition caused by obstruction of blood flow to the heart, leading to cardiomyocyte necrosis. This process begins with the formation of atherosclerotic plaques that cause total occlusion of the coronary artery lumen, resulting in myocardial ischemia. When transmural ischemia lasts for 20–40 minutes, cardiomyocyte necrosis occurs. Methods: This study aimed to des…
Latar belakang: Angular Cheilitis merupakan suatu keadaan inflamasi akut atau kronik yang dapat terjadi di sekitar sudut mulut dan meluas ke kulit ditandai adanya kemerahan, retakan, rasa nyeri, dan tanda lainnya. Keadaan ini lebih sering terjadi pada anak – anak terutama pada anak panti asuhan yang disebabkan oleh berbagai faktor penyebab seperti defisiensi nutrisi terutama pada kondisi keku…
Background: Heat-cured acrylic resin is one of the commonly used dental materials for the manufacture of denture bases. Color stability in acrylic resins is one of the most important clinical signs of aging or material deterioration after a long period of use, which can affect aesthetics. Factors that can affect the color stability of heat-cured acrylic resin includes acidic foods/beverages. Pe…
Background: Type 2 Diabetes Mellitus (T2DM) was a chronic metabolic disease with an increasing prevalence, accompanied by hepatic complications such as Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD). The duration of T2DM affected the severity of metabolic disturbances, insulin resistance, and hepatic fat accumulation. However, data on the incidence of MAFLD at RSUP Dr. Mohammad …
Background. Low back pain (LBP) is one of the most common musculoskeletal complaints and can adversely affect physical function, quality of life, and patient productivity. Vitamin D deficiency, assessed through serum 25-hydroxyvitamin D (25-OH D) levels, plays a role in pain modulation, muscle function, and inflammatory responses, and is suspected to be associated with LBP occurrence. This stud…
Urothelial carcinoma is the most common malignancy of the urinary tract and exhibits a wide range of clinicopathological characteristics that influence prognosis and patient management. Local data regarding the clinicopathological characteristics of urothelial carcinoma in Palembang remain limited; therefore, this study was conducted to provide a more representative overview. This study was a d…
Background: Chronic Kidney Disease (CKD) is a progressive condition that requires long-term hemodialysis treatment. Hemodialysis results are greatly influenced by vascular access, especially Arteriovenous Shunt (AV Shunt) as permanent access and Double Lumen Catheter (CDL) as temporary access. The difference between the patient's characteristics and the clinical condition is often a factor in t…
Introduction: Neonatal sepsis is a clinical syndrome of systemic disease accompanied by bacteremia in infants within the first month of life. Neonatal sepsis is one of the main causes of morbidity and mortality, both in full-term and premature infants. Cases of neonatal sepsis in Indonesia are quite high, including in high-risk groups such as male infants. The purpose of this study was to deter…
Background: Bone marrow trephine biopsy is an essential diagnostic procedure for hematological diseases through assessment of morphology, fibrosis, cellularity, and tumor involvement. Since 2023, Dr. Mohammad Hoesin General Hospital Palembang has routinely performed bone marrow biopsies; however, clinicohistopathological data remain limited. This study aimed to describe the bone marrow clinicoh…
Background: Acute coronary syndrome (ACS) is a heart disorder characterized by the sudden decrease of blood supply to the heart due to the narrowing of the coronary blood vessels. Acute coronary syndrome is based on risk factors such as age, gender, and lifestye. An abnormal lipid profile due to an unhealthy lifestyle is also one of the risk factors of acute coronary syndrome. This study aims t…
Background: Coronary Artery Bypass Graft (CABG) is a myocardial revascularization procedure aimed at restoring blood flow to the heart in patients with coronary artery disease. Postoperative evaluation of functional capacity is important to assess the effectiveness of cardiac recovery, particularly during phase I of cardiac rehabilitation. The Six-Minute Walk Test (6MWT) is a simple and safe me…
Background: Short-term memory is a chemical process between neurons in processing and storing information in a small and short duration. Memorizing the Qur'an can induce neuroplasticity through the Long-term Potentiation (LTP) mechanism, thus strengthening synaptic connections that will implement in increasing memory acuity and brain intelligence. This study aims to determine relationship betwe…
Latar belakang: Resin komposit packable konvensional memiliki kandungan filler yang tinggi dengan kekuatan fleksural yang tinggi. Namun, resin komposit packable memiliki viskositas yang tinggi sehingga sulit mengisi kavitas yang kecil. Highly filled flowable composite merupakan generasi baru dari resin komposit flowable dengan kandungan filler yang lebih tinggi sehingga tidak hanya digunakan un…
Background: Sexual harassment is a serious and widespread human rights violation, encompassing physical, verbal, or psychological acts without the victim's consent, occurring in various contexts such as households, workplaces, and educational institutions. Its impact is severe, including depression and decreased quality of life. Among students, cases of sexual harassment continue to increase, e…
Cervical cancer is the fourth most common cancer in the world, with a total of 569,847 cases and 311,365 deaths in 2018. Cervical cancer ranks as the second-highest cause of death in women . This study aims to determine the prevalence , age distribution , and distribution of histopathology subtypes based on the World Health Organization 2014 classification , the location of metastasis, the rela…
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, with 150,000 new cases yearly. Roughly 40% of patients who receive rituximab in addition to vincristine, cyclophosphamide, doxorubicin, and prednisone treatment have primary refractory disease or recurrence. Although the Ann Arbor stage could determine DLBCL prognosis, new biomarkers are needed to stratify patient pro…
Background: Sarcopenia is a condition characterized by a decrease in muscle mass accompanied by a reduction in muscle strength and/or physical performance, which frequently occurs in older adults and leads to an increased risk of falls, dependency, cognitive and cardiopulmonary function decline, lower quality of life, mortality, and high healthcare costs. Calf circumference is recommended as a …
Background: Morbus Hansen (MH), also known as leprosy, is a chronic infectious disease caused by Mycobacterium leprae that primarily affects the skin and peripheral nerves. Despite global elimination efforts, MH remains a public health problem in Indonesia. Histopathological examination plays an essential role in establishing the diagnosis and determining the disease spectrum. This study aimed …
Background: The eyelids in humans have a vital role in protecting the eyes from the external environment and foreign objects. The skin of the eyelids is not only the thinnest skin of the body but also the part that is often exposed to sunlight, in addition the eyelids are also the most sensitive part of the body, making it possible to contract benign or malignant tumors. This study purpose is t…
Acute Kidney Injury (AKI) is a clinical syndrome of sudden decrease in glomerular filtration rate. Several risk factors for pediatric GgGA include sociodemographics, congenital diseases, and renal replacement therapy (RRT). GgGA is often found in hospitalized sick children and is at high risk of death. This study used analytic research with a cross sectional approach. Subjects were taken using …
Background: Gastric malignant tumors are the sixth most common malignancy in the world and the fourth leading cause of cancer death in the world. Approximately 90% of gastric malignant tumor cases originate from the epithelium, namely adenocarcinoma. The etiology and main risk factors for gastric malignant tumors are caused by Helicobacter pylori infection. Symptoms of gastric malignant tumors …
Obesity is a condition characterized by excess body fat, leading to various health issues, including histological changes in organs such as the spleen (lien). This study aims to compare the histological features of the spleen in an obesity mouse model treated with Moringa oleifera leaf extract to investigate its potential effects on obesity-induced histological alterations. This experimental st…
Obesitas merupakan masalah kesehatan global yang berkaitan dengan inflamasi sistemik, termasuk inflamasi lobular pada hati yang memicu perkembangan Non-Alcoholic Fatty Liver Disease (NAFLD). Ekstrak daun kelor (Moringa oleifera) dikenal memiliki efek antioksidan dan antiinflamasi yang potensial untuk menurunkan inflamasi tersebut. Penelitian ini menggunakan desain deskriptif observasional denga…
Low Birth Weight (LBW) is a leading cause of infant mortality and is associated with various long-term complications, such as growth and developmental disorders. Maternal characteristics and behaviors during pregnancy are believed to influence the incidence of LBW. This study aims to explore this relationship. A cross-sectional analytical study was conducted involving 55 mothers who delivered b…
Background: Anemia is a common health problem among adolescent girls and can lead to decreased productivity, learning concentration, and academic performance. Medical students are expected to have good knowledge and attitudes toward anemia prevention; however, such understanding is not always reflected in preventive behaviors. Objective: This study aimed to determine the relationship between kn…
Latar belakang: Candida albicans merupakan jamur yang dapat menyebabkan kandidiasis psuodomembran atau oral trush, yang apabila tidak dirawat dapat menyebar ke aliran darah dan menyebabkan sepsis dan syok sepsis. Menyikat gigi dengan pasta gigi dapat mengontrol plak secara kimiawi. Kombinasi fluoride dan ekstrak gambir terbukti dapat menghambat pertumbuhan C. albicans, kombinasi kedua bahan ter…
Latar belakang: Aggregatibacter actinomycetemcomitans adalah bakteri gram negatif yang paling sering ditemukan pada periodontitis. Daun sirih merah sebagai bahan alami dilaporkan memiliki kandungan senyawa berupa flavonoid, alkaloid, tanin, saponin dan minyak atsiri yang terbukti memiliki efek antibakteri. Tujuan: Mengetahui ada atau tidaknya aktivitas antibakteri ekstrak daun sirih merah (Pipe…
Background: The use of contact lenses continues to increase among university students, both for cosmetic purposes and refractive correction. However, improper usage behavior may increase the risk of complications, particularly when hygiene and wearing duration are not adequately managed. This study aimed to describe the compliance level regarding contact lens use among medical students at the F…