The number of diabetes mellitus cases continues to increase each year. Antidiabetic drugs are essential for individuals with diabetes, particularly type 2, to control blood glucose levels. However, commonly used modern antidiabetic drugs are often associated with adverse side effects. Therefore, natural products such as karamunting leaves (Rhodomyrtus tomentosa (Aiton) Hassk.) have been investi…
Background: Nosocomial infections remain a major problem with high incidence rates globally and in Indonesia, contributing to morbidity and mortality, especially with the increasing antibiotic resistance including Serratia marcescens, a multidrug-resistant organism and a common Gram-negative pathogen in ICUs. Indonesia is rich in herbal plants, one of which is karamunting leaf (Rhodomyrtus tome…
Backgrounds: Escherichia coli is a bacteria that often causes serious infections, such as digestive tract, urinary tract and bloodstream infections. One of the main obstacles in its treatment is the ability of these bacteria to form biofilms, which increase resistance to antibiotics and protect against external influences. Uncontrolled use of antibiotics further exacerbates the problem of resis…
ABSTRAK Luka terbuka dapat berpotensi mengalami infeksi kronik jika tidak diobati. Daun karamunting (Rhodomyrtus tomentosa (Ait) Hassk) mengandung zat utama rhodomyrtone serta flavonoid, tanin, saponin, fenol dan steroid sebagai antibakteri, antiinflamasi dan antioksidan yang dapat membantu proses penyembuhan luka. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol daun…
Uji toksisitas subkronis kombinasi fraksi n-heksana dan etil asetat daun Karamunting (Rhodomyrtus tomentosa) pada tikus putih jantan dilakukan untuk mengetahui keamanan setelah pemberian sediaan uji secara berulang. Uji toksisitas kombinasi fraksi daun karamunting dilakukan selama 28 hari pemberian sediaan uji dan ditambah 14 hari untuk pengamatan efek yang tertunda pada tikus. Ada 4 kelompok m…