Excessive free radical production can lead to oxidative stress that damages DNA, proteins and lipids, triggering serious neurodegenerative and autoimmune diseases. Oxidative damage caused by free radicals can be prevented by the activity of antioxidant compounds. Based on previous research, papaya leaves, melinjo leaves, and pelawan leaves as natural antioxidants contain flavonoids and phenolic…
The ethanol extract of Pelawan leaves (Tristaniopsis merguensis Griff.) contains flavonoids, steroids, phenolics, and terpenoids, which have the potential to act as analgesics and anti-inflammatory agents due to their ability to inhibit prostaglandin formation, the main mediator of pain and inflammation. This study aimed to evaluate the characteristics of the extract as well as the analgesic an…
The use of antioxidants can prevent oxidative stress conditions, which cause tissue damage, due to too many free radicals in the body. The body produces antioxidant compounds such as SOD (Superoxide Dismutase), Gpx (Glutathione peroxidase), and catalase to protect the endothelium of blood vessels from free radical attacks, which reduce oxidative stress. This study aims to evaluate the antioxida…
Free radicals trigger oxidative stress through an increase in Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) which leads to degenerative diseases such as cancer, cardiovascular diseases, and others. Antioxidants are needed to protect from free radicals. One of the plants that has potential as a natural antioxidant is pelawan leaves (Tristaniopsis merguensis Griff). Secondary …