Staphylococcus aureus and Escherichia coli bacteria can cause serious infections, especially when the immune system is low. The use of antibiotics is often the choice in treating infections, but bacterial resistance to antibiotics is increasing. Therefore, the search for alternative antibacterials from natural sources is important. One potential plant is the kenikir leaf (Cosmos caudatus). This…
Kenikir leaves (Cosmos caudatus Kunth.) contain flavonoid group compound quercetin which has potential as anti-cancer. The extract of kenikir leaves has low solubility and bioavailability so that a modification of the drug delivery system is needed in the form of folic acid-conjugated chitosan-alginate polymer-based nanoparticles. Folic acid-conjugated chitosan carries the drug to folate recept…