The utilization of sweet orange peel is still minimal as it is often overlooked after fruit processing for consumption, despite being rich in bioactive compounds, including flavonoids, especially for topical preparations. Previous research has mainly focused on conventional formulations with limitations in skin penetration. The Nanostructured Lipid Carrier (NLC) delivery system can enhance perc…
Herpes Simplex Virus Type-1 (HSV-1) is a common virus responsible for skin and genital infections. This research employs an in silico approach to predict the target mechanisms of sweet orange (Citrus sinensis) peel extract against HSV-1. The investigated peel extract is known for its antiviral properties aimed at preventing HSV-1 infection through molecular interactions. SwissTargetPrediction a…
Background: Discolored teeth can be treated through bleaching that is aimed at restoring the white color of the teeth. Previous studies showed that teeth whitening from hydrogen peroxide application can be improved by repeated its applications, however the use of this material still causes tooth surface roughness. 2.5% tangerine peel extract reported to have the potential to be an alternative b…
Background: Root canal preparation produced a layer called smear layer. Irrigant solution used to eliminate microorganism, debris, and smear layer. Lemon (Citrus limon) peel is one of natural resources that has active compounds to eliminate smear layer from root canal. This study aims to determine the effectiveness of lemon peel (Citrus limon) extract 5%, 10%, 15%, 20% as final root canal treat…
Latar Belakang: Jeruk menduduki peringkat 3 besar sebagai komoditas unggul buah tahunan Indonesia. Salah satu varietas jeruk unggulan Indonesia adalah jeruk keprok medan (Citrus nobilis). Bagian kulit jeruk keprok medan diketahui mengandung senyawa aktif antibakteri berupa, flavonoid, tanin, saponin, dan triterpenoid yang mampu menghambat pertumbuhan bakteri Gram positif. Tujuan: Tujuan penelit…