Background. Cervical cancer is a malignancy of the cervical epithelium primarily caused by infection with the Human Papillomavirus (HPV). In 2022, GLOBOCAN reported 36,964 new cases and 20,708 deaths due to cervical cancer. Hematological inflammatory parameters can reflect systemic inflammation that correlates with cancer severity. This study aimed to analyze the association between hematologic…
Background: The liver is a vital organ essential for metabolism, detoxification,and nutrient storage but is highly vulnerable to damage from exposure to toxic substances like CCl4. This compound can rapidly induce liver fibrosis. Purple sweet potato (Ipomoea batatas L.), a plant widely consumed in Indonesia, is predominantly used for its tubers, while its leaves are often neglected. However, th…
Kanker ovarium, khususnya subtipe serous, merupakan penyebab kematian utama kanker ginekologi pada perempuan. Keterlambatan diagnosis dan pengobatan yang kurang efektif merupakan salah satu penyebab tingginya angka kejadian dan mortalitas. Faktor risiko yang dapat dimodifikasi seperti indeks massa tubuh (IMT) dan paritas diyakini memiliki potensi pencegahan terhadap karsinoma ovarium subtipe se…
Introduction: Gestational trophoblastic disease is a spectrum of condition that has a potential progression of malignancy, with characteristics of proliferation of the trophoblasts. Lesions including hydatidiform mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor. Hydatidiform mole is an unsuccessful pregnancy with abnormal proliferation of chorionic villi caused by hy…
Background. The mosi common breast carcinomas are ductal (40-70%) and lobular (5-15%) types. They have distinct histopathologycal features, but the challenge for the pathologists are sometimes boih features can appears on the same tumor in confusing pattern. Jn order to help distinguishing this two types carcinomas, there are many researchs for E-cadherin expression and proven as usefitl tools.…
Background. Triple negative breast cancer (TNBC) is defined as a subtype that is negative for estrogen receptor, progesterone receptor and HER-2,accounts for 10-70% ofall breast cancer.TNBC have aggressive behavior, poor prognosis, unique clinicohistopathologic characteristic and molecular profiles. This study designedto identified characteristics andfactors are had relationship with TNBC subty…
Kanker payudara adalah kanker yang terjadi pada payudara. Kanker payudara merupakan salah satu kanker yang paling sering menyerang wanita di dunia dan menempati urutan tertinggi pertama di Indonesia. Di Indonesia diperkirakan terdapat 100 penderita kanker baru untuk setiap 100.000 penduduk per tahunnya. Penelitian ini bertujuan untuk mengetahui insidensi dan sebaran gambar karsinoma mammae di b…
Osteosarkoma disebut juga osteogenik sarkoma adalah suatu neoplasma ganas yang berasal dari sel primitif (poorly differentiated cells) di daerah metaflse tulang panjang. Sejauh ini penelitian mengenai karakteristik osteosarkoma masih sangat sedikit. Penelitian ini bertujuan untuk mengetahui karakteristik histopatologi penderita osteosarkoma periode lima tahun mulai Januari 2007 sampai dengan De…
Introduction: Cholecystitis is inflammation of the gallbladder due to cystic duet obstruetion due to cholelithiasis. Prevalence of cholecystitis in Indonesia is relatively lower compared to westem countries. Cholecystitis cases are found about 10% in the population, about 90% of cases associated with gallstones, while the remaining 10% not cholecystitis. Delay diagnosis of acute cholecystitis w…
Background: Benign prostate hyperplasia (BPH) and prostate carcinoma are two types of proliferative lesions that are often found in the prostate gland. The incidence of BPH and prostate carcinoma are increasing with age. On histopathological examination of BPH varied comorbid lesions can be found. Histopathological examination to determine subtypes and Gleason score used as predictor of prostat…
Background: Mature teratoma is a rare tumour which consists of multiple cell types and tissues derived from three germinal layers. This tumour is usually found in the midline of the body, and occurs at any age. There are only few studies that have been conducted so far to describe profile (age, sex, location) and histopathological feature (germinal layer), especially in Indonesia. The aim of th…
Endometrial cancer is the third most gynecological cancer in Indonesia. In 2005, endometrial cancer is the fourth most gynecologic cancer observed at Obstetrics Gynecology Department of Mohammad Hoesin Hospital Palembang. This study is aimed to determine the prevalence of endometrial carcinoma at the Laboratory Pathology Anatomy, Mohammad Hoesin Hospital Palembang. Method: This study used a des…
tew/gw prostatic hyperplasia (BPH) adalah pembesaran jinak kelenjar prostat yang banyak diderita oleh laki-laki. Pada tahun 2010, diperkirakan ada 92,4 juta kasus BPH pada laki-laki yang berusia di atas 50 tahun di tujuh negara yaitu Amerika, Jepang, Francis, Jerman, Italia, Spanyol dan Inggris. Di Indonesia Khususnya Sumatera Selatan, prevalensi BPH belum diketahui. Selain itu, berdasarkan pen…