Background The prognosis of advanced-stage lung cancer remains poor despite ongoing therapeutic advances. Systemic inflammation and nutritional status are increasingly recognized as important prognostic determinants. The Advanced Lung Cancer Inflammation Index (ALI) is a prognostic parameter that evaluates the degree of systemic inflammation by combining body mass index (BMI), serum albumin lev…
Cervical cancer is one of the leading causes of morbidity and mortality among women, making early detection of precancerous lesions essential. However, lesion segmentation in cervical images still faces several challenges, including unclear object boundaries, illumination variations, imaging artifacts, and class imbalance between lesion and background, which reduce the performance of deep learn…
Cervical cancer is a leading cause of death among women. The subjectivity of Visual Inspection with Acetic Acid (VIA) screening encourages the use of Artificial Intelligence (AI) for medical image segmentation automation. However, limited datasets frequently cause model overfitting. This research aims to improve the segmentation performance of cervical precancerous images on the YOLOv11-seg mod…
Visual diagnosis via colposcopy is prone to observer subjectivity, making a more objective computational system necessary. This study explores two approaches: hybrid feature engineering (color, texture, contour) using machine learning (ML) via a rule-based system that adapts the Sweden score method, and end-to-end architectures based on YOLO (v8, v11, v12, v26). The dataset is sourced from the …
Background: Gastric adenocarcinoma remains a global health burden with high mortality, while effective targeted therapies are still limited. Claudin-18.2 is a transmembrane tight-junction protein selectively expressed in normal gastric mucosa and retained in gastric adenocarcinoma. Its role as a novel therapeutic target, including zolbetuximab, highlights the importance of investigating claudin…
Latar belakang: Karsinoma ovarium epitelial merupakan keganasan ginekologi dengan mortalitas tinggi dan sebagian besar terdiagnosis pada stadium lanjut. Vitamin A dan reseptor vitamin A diduga berperan dalam regulasi proliferasi dan diferensiasi sel, sedangkan CA-125 merupakan biomarker yang luas digunakan untuk menilai beban tumor dan memantau respons terapi. Namun, data mengenai hubungan kada…
Breast cancer is the most common cancer in women with a percentage of 30% of cancer cases every year. Mastectomy is a treatment that can be performed on breast cancer patients. Mastectomy has a physical and psychological impact on the patient. Sexual function problems are a psychological impact that occurs in breast cancer patients after mastectomy. Sexual function is one of the basic human asp…
Background. Breast lymphoma is a blood malignancy that can be seen as a primary tumor (primary breast lymphoma/PBL) or a secondary manifestation of lymphoma that arises from different parts of the body. Although it is rarer than breast cancer (BC), it has a worse prognosis than BC. This study aims to determine the number of cases and distribution of characteristics of breast lymphoma at Dr. Moh…
The prevalence of breast cancer among younger populations continues to increase and has become a global health concern. Female adolescents represent a critical target group for breast cancer prevention, as the formation of health-related knowledge and behaviors begins during adolescence. This study aimed to describe the level of knowledge among female adolescents regarding breast cancer prevent…
Colorectal cancer is a leading cause of cancer-related deaths globally, predominately developing from adenomatous polyps. While colonoscopy is the gold standard for polyp detection, it suffers from a miss rate of 26% due to operator fatigue and visual variability. This study aims to develop a real-time Computer-Aided Diagnosis (CADx) system for polyp segmentation using the efficient YOLOv11-Seg…
Cervical cancer is the fourth most common cancer in the world, with a total of 569,847 cases and 311,365 deaths in 2018. Cervical cancer ranks as the second-highest cause of death in women . This study aims to determine the prevalence , age distribution , and distribution of histopathology subtypes based on the World Health Organization 2014 classification , the location of metastasis, the rela…
This research presents the implementation and evaluation of a LightWeight Vision Transformer (ViT) architecture for classifying seven different types of skin cancer using medical dermoscopic images from the HAM10000 dataset. The methodology includes data preprocessing, class balancing using Random Oversampling, and splitting the dataset into training and testing sets. Several hyperparameter con…
Kidney and urinary tract diseases in children can cause complications such as acute and chronic kidney disease. Proteinuria is an important marker for early detection. Dipstick urinalysis, manual or automated, is widely used for its speed and simplicity, though accuracy may differ. No study has compared these methods at Kemenkes RS Dr. Mohammad Hoesin Palembang. This descriptive comparative stu…
Background: Bladder cancer is a prevalent urological malignancy strongly linked to exposure to tobacco-derived carcinogens, yet the influence of smoking behavior on its clinical and histopathological characteristics remains inconsistent across populations. Objective: This study aimed to assess the association between smoking status and both histopathological grading and clinical staging among p…
Mola Hidatidosa adalah suatu kegagalan proses reproduksi yang secara histologis tampak jaringan trofoblast sebagian atau seluruhnya menunjukkan gambaran degenerasi hidrofik dan hiperplasia. Penyebab Mola sampai saat ini belum terjawab. Berbagai teori telah dikemukakan, tetapi belum mampu menjawab secara tuntas. Walau demikian ada beberapa faktor-faktor yang termasuk kelompok resiko tinggi antar…
Breast cancer is the most common type of cancer in the world. Chemotherapy can be one of the treatment options and has been proven to have a significant impact on patient survival. However, there are concerns about the side effects of chemotherapy that can affect the cognitive function of patients, known as chemotherapy-induced cognitive impairment (CICI). This study aims to determine the cogni…
Chemotherapy is the main treatment for breast cancer; however, it may cause cognitive impairment, known as chemobrain, which is characterized by a decline in memory, attention, reasoning, concentration, processing speed, executive function, and visual ability. Clinicopathological factors such as age, education, marital status, cancer stage, type and number of chemotherapy cycles are believed to…
Background: Lung cancer is the world's highest cancer case at 12.4% and in Indonesia the second largest with a percentage of 9.5% so it needs attention from health workers, families and communities. Patients with lung cancer will feel chronic pain caused by tumor infiltration and nerve suppression. Therefore, in addition to pharmacological therapy, it is necessary to provide non-pharmacological…
Background: Endometrial carcinoma is an epithelial malignancy that occurs in the endometrium, the innermost layer of the uterine wall. Endometrioid endometrial carcinoma is the most common histopathological type of endometrial carcinoma. This type is associated with estrogen exposure without progesterone (unopposed estrogen) and risk factors such as advanced age, obesity, and nulliparity. Study…
The most common symptoms in patients with cervical cancer are bleeding, pain during intercourse, and vaginal discharge. In advanced stages, symptoms will develop into low back or lower abdominal pain due to tumor pressure in the pelvic region laterally to ureteral obstruction, even to oligo or anuria. The results of the assessment found the same nursing problems in the three patients managed, n…
Background: Endometrial cancer is a gynecologic malignancy that originates from the endometrial lining. It ranks as the sixth most common cancer among women worldwide. The survival rate of patients with endometrial cancer is influenced by several factors, including age, stage, histopathological type, grade, and treatment modalities. This study aims to determine the survival rate of patients wit…
Background: Cervical cancer is the second most common type of cancer in Indonesia. Cervical cancer is most often found when it is already in the invasive, advanced, or even terminal stages with the main complaint being pain caused by tumor infiltration. Continuous pain can affect daily activities and the quality of life of cervical cancer patients. One of the non-pharmacological pain treatments…
Colon carcinoma is one of the most common malignancies of the lower gastrointestinal tract with high incidence and mortality rates worldwide, including in Indonesia. Most patients are diagnosed at an advanced stage with a poorer prognosis. This study aimed to determine the profile and clinical as well as inflammatory characteristics of colon carcinoma patients at RSUP Dr. Mohammad Hoesin Palemb…
Chronic pain in untreated ovarian cancer patients affected quality of life, led to psychological disturbances, physical issues, and caused discomfort. The finger hold relaxation technique helped ovarian cancer patients cope with pain, as this technique provided a sense of comfort that helped free mental and physical conditions, thereby increasing tolerance to pain. The purpose of this scientifi…
Breast cancer is one of the leading causes of death among women worldwide. Early detection of breast cancer is crucial to increase the chances of recovery. This study aims to develop a breast cancer classification system using the Convolutional Neural Network (CNN) method with ResNet-50 and VGG-16 architectures. The data used in this study are breast ultrasound images obtained from a public dat…
Background. Cervical cancer is a malignancy of the cervical epithelium primarily caused by infection with the Human Papillomavirus (HPV). In 2022, GLOBOCAN reported 36,964 new cases and 20,708 deaths due to cervical cancer. Hematological inflammatory parameters can reflect systemic inflammation that correlates with cancer severity. This study aimed to analyze the association between hematologic…
Background: Hepatoma, or hepatocellular carcinoma, is the primary liver tumor accounting for 90% of liver tumor cases. In certain cases, hepatoma patients only undergo laboratory examinations without radiological imaging. An alternative method is needed to monitor tumor progression, predict patient prognosis, and determine appropriate treatment without radiological examinations, namely by measu…
Cervical cancer is the main cause of cancer death among woman and the third most cancer case in the world. High expression of VEGF in cervical cancer is linked to a poor prognosis, therefore anti-VEGF therapy has an important role in cervical cancer resolution. Several studies show that emodin inhibit proliferation, migration, and a formation of endothelial cells stimulated by VEGF. This resear…
Cervical cancer is a malignancy of the cervix wall with a high prevalence among women worldwide, ranking third after breast and colorectal cancer. The disease is primarily caused by Human Papillomavirus (HPV) infection, with HPV types 16 and 18 being the leading cause in more than 70% of cases. Cervical cancer patient survival is influenced by various factors, including stage, histopathology ty…
Background: Breast cancer is a type of cancer with a high prevalence in Indonesia. The quality of life of breast cancer patients undergoing chemotherapy can be influenced by many factors, which require assessment using instruments such as the EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30). Methods: This study used a descriptive o…