Background: Lung cancer is a malignant tumor originating from lung tissue, including the respiratory epithelium. It is one of the leading causes of cancer-related mortality worldwide and is frequently diagnosed at an advanced stage with a poor prognosis. Systemic inflammation and nutritional status play important roles in disease progression and patient survival. The modified Glasgow Prognostic…
Background: Dental caries was one of the most common chronic diseases among schoolaged children, with prevalence rates of 84.8% in children aged 5–9 years and 63.8% in those aged 10–14 years based on the 2023 Indonesian Health Survey. High consumption of added sugar and low levels of knowledge regarding its impact on oral health were identified as contributing factors. This condition highli…
Background: Parental knowledge plays an important role in maintainingoral health of children with physical disabilities who have motor limitations anddepend on parents for dental care. Objective: To analyze the relationship betweenparents’ level of knowledge and dental caries in children with physical disabilitiesat SLB D YPAC Palembang City. Methods: A descriptive-analytical quantitativestud…
Background: Dental anxiety is a primary barrier in pediatric dental care that causes treatment refusal and poor oral health. The Tell-Play-Do (TPD) method using a smartphone dentist game is a modification of conventional behavior management that potentially reduces anxiety through interactive education and distraction. Objective: This study aims to determine the effect of the TPD behavior manag…
Background: Oral health in visually impaired children required special attention because visual limitations could affect their ability to maintain oral hygiene independently, increasing the risk of plaque accumulation and oral diseases. The selection of toothbrush type and proper brushing technique were important factors in controlling plaque in these manual and sonic electric toothbrushes in v…
Nekrosis pulpa pada gigi permanen muda menyebabkan terhentinya perkembangan akar sehingga gigi rentan mengalami fraktur. Perawatan yang bertujuan meregenerasi kompleks dentin-pulpa pada gigi permanen muda yang mengalami nekrosis adalah prosedur endodontik regeneratif. Kitosan telah digunakan sebagai scaffold pada prosedur tersebut, akan tetapi potensi regeneratifnya belum cukup optimal. Fucoida…
Background: Orthodontic treatment using clear aligners or fixed appliances often causes pain in patients. This pain may affect comfort and compliance during orthodontic therapy. Objective: This study aims to determine whether there is a difference in pain intensity among malocclusion patients undergoing treatment with clear aligners compared to fixed orthodontic appliances. Methods: This resear…
Background. Anaplastic Large Cell Lymphoma (ALCL) is a mature T-cell lymphoma characterized by strong CD30 expression and is classified into ALK-positive and ALK-negative subtypes. Although both subtypes share similar histopathological features, differences in ALK expression are associated with distinct biological behavior, treatment response, and prognosis. International studies have reported …
Blind children are a group of children who have limited vision or are totally blind. Blind children have obstacles in communication, limited learning media, and lack of teaching resources. A survey from the World Health Organization (WHO) shows that blind children under 15 years of age have worse dental and oral health than normal children. This is because blind children have difficulty detecti…
Introduction: Sepsis is a leading cause of morbidity and mortality in critically ill patients. While estradiol administration shows potential as a sepsis therapy, its impact on the necroptosis process remains unclear. This study aims to investigate the effect of estradiol administration on necroptosis and inflammation in a sepsis-induced Wistar rat model. Methods: This experimental study employ…
Health is a basic need that supports people’s daily activities and productivity. Hospitals, as referral health care facilities, are required to provide high-quality services in line with the implementation of the National Health Insurance (JKN) program through BPJS Kesehatan. Various problems such as limited health personnel, service time, attitudes of medical staff, and the quality of facili…
Latar Belakang: Stomatitis Aftosa Rekuren (SAR) merupakan sariawan berulang tanpa penyakit sistemik yang dapat mengganggu kualitas hidup, terutama pada mahasiswa. Salah satu faktor predisposisinya adalah pola makan yang tidak seimbang yang dapat menyebabkan defisiensi nutrisi dan menurunkan imunitas. Tujuan: “Mengetahui hubungan antara rekurensi SAR dengan jenis, jumlah, dan frekuensi pola ma…
Klebsiella pneumoniae is a Gram-negative bacterium that can cause various infectious diseases, including pneumonia. Throughout its history, this bacterium has developed resistance to antibiotics. K. pneumoniae exhibits various resistance strategies, including enzymatic modification, gene mutations, and increased efflux pumps. The increasing prevalence of resistance each year has become a key fa…
Free radicals are molecules with unpaired electrons that can cause tissue damage through oxidative stress, accelerate aging, and trigger various diseases, including cancer. Antioxidants play an important role in warding off free radicals. Purple sweet potato leaves (Ipomoea batatas L.) are known to contain active compounds such as polyphenols, flavonoids, tannins and triterpenoids which have hi…
Background: Malocclusion is commonly encountered conditions, with the global prevalence reaching 56% and up to 80% in Indonesia. One of the most frequent types of malocclusion is dental crowding. Moderate to severe dental crowding often requires premolar extraction to provide adequate space during fixed orthodontic treatment. Premolar extraction is a widely used strategy to improve dental align…
Xerostomia was closely associated with hyposalivation, which had negative impacts on oral health and led to a decreased quality of life in patients; therefore, it was necessary to increase the salivary flow rate. Gambir contained catechins and tannins, which were reported to be able to increase salivary flow rate.Objective: To determine the effect of gargling gambir solution on salivary flow ra…
Background: Tooth extraction is the most frequently performed treatment in dentistry, with a rate reaching 7.9%. The impact of tooth extraction is alveolar bone resorption, so alternative treatments are needed that can accelerate alveolar bone regeneration with natural ingredients, namely catfish collagen. Objective: To determine the benefits and effects of administering catfish collagen on the…
Porphyromonas gingivalis is the main anaerobic bacterium responsible for gingivitis and periodontitis. The use of natural ingredients such as pineapple (Ananas comosus) and stevia has potential as antibacterial agents capable of inhibiting and even killing Porphyromonas gingivalis, and can be developed into products in the form of jelly candy. This study aimed to determine the antibacterial act…
Background: Food allergy is one of the most common health problems in children, with prevalence increasing annually. However, many parents often misinterpret their children's symptoms as food allergies, even though food may not necessarily be the cause. Given the rising incidence of food allergies and the misunderstanding among parents, this study aims to determine the prevalence of food allerg…
Background: Pediatric intensive care unit (PICU) patients are in critical condition, requiring a clear understanding of admission indications, treatment priorities, and patient outcomes. Mapping these profiles is important to describe case patterns in the PICU at Dr. Mohammad Hoesin General Hospital in Palembang and to serve as a basis for evaluating and improving service quality. Objective: To…
Background: Hypertensive disorders in pregnancy remain one of the leading causes of maternal and fetal morbidity and mortality worldwide. These conditions may result in serious complications such as preeclampsia, eclampsia, and fetal growth restriction. Calcium requirements increase significantly during the third trimester to support fetal bone mineralization, while calcium deficiency has been …
Background. Breast lymphoma is a blood malignancy that can be seen as a primary tumor (primary breast lymphoma/PBL) or a secondary manifestation of lymphoma that arises from different parts of the body. Although it is rarer than breast cancer (BC), it has a worse prognosis than BC. This study aims to determine the number of cases and distribution of characteristics of breast lymphoma at Dr. Moh…
Background: Free radicals are reactive compounds that can cause oxidative stress and are related to diseases in the oral cavity, such as periodontitis. Semendo arabica coffee is rich of tannins, flavonoids, and polyphenol compounds that can neutralize free radicals. Semendo arabica coffee extract was reported to have antioxidant activity, therefore in this study it was developed into a jelly ca…
Background: Pulmonary tuberculosis (TB) is a chronic contagious infection caused by Mycobacterium tuberculosis. Tuberculosis is a public health problem that has become a global challenge. Non-adherence to treatment is one of the biggest obstacles in treating TB in the world, and is the factor that contributes most to treatment failure. The aim of this research is to determine the level of educa…
Latar belakang: Angular Cheilitis merupakan suatu keadaan inflamasi akut atau kronik yang dapat terjadi di sekitar sudut mulut dan meluas ke kulit ditandai adanya kemerahan, retakan, rasa nyeri, dan tanda lainnya. Keadaan ini lebih sering terjadi pada anak – anak terutama pada anak panti asuhan yang disebabkan oleh berbagai faktor penyebab seperti defisiensi nutrisi terutama pada kondisi keku…
Background: Heat-cured acrylic resin is one of the commonly used dental materials for the manufacture of denture bases. Color stability in acrylic resins is one of the most important clinical signs of aging or material deterioration after a long period of use, which can affect aesthetics. Factors that can affect the color stability of heat-cured acrylic resin includes acidic foods/beverages. Pe…
Introduction: Neonatal sepsis is a clinical syndrome of systemic disease accompanied by bacteremia in infants within the first month of life. Neonatal sepsis is one of the main causes of morbidity and mortality, both in full-term and premature infants. Cases of neonatal sepsis in Indonesia are quite high, including in high-risk groups such as male infants. The purpose of this study was to deter…
Background: Acute coronary syndrome (ACS) is a heart disorder characterized by the sudden decrease of blood supply to the heart due to the narrowing of the coronary blood vessels. Acute coronary syndrome is based on risk factors such as age, gender, and lifestye. An abnormal lipid profile due to an unhealthy lifestyle is also one of the risk factors of acute coronary syndrome. This study aims t…
Background: Short-term memory is a chemical process between neurons in processing and storing information in a small and short duration. Memorizing the Qur'an can induce neuroplasticity through the Long-term Potentiation (LTP) mechanism, thus strengthening synaptic connections that will implement in increasing memory acuity and brain intelligence. This study aims to determine relationship betwe…
Latar belakang: Resin komposit packable konvensional memiliki kandungan filler yang tinggi dengan kekuatan fleksural yang tinggi. Namun, resin komposit packable memiliki viskositas yang tinggi sehingga sulit mengisi kavitas yang kecil. Highly filled flowable composite merupakan generasi baru dari resin komposit flowable dengan kandungan filler yang lebih tinggi sehingga tidak hanya digunakan un…