Background. Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by inflammation and multi-organ involvement. Its management requires a long-term multidisciplinary approach, which poses challenges for patients to maintain medication adherence. Poor adherence often leads to inadequate disease control, as reflected by higher disease activity, and worsened prognosis. T…
Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a wide spectrum of clinical manifestations, ranging from mild cutaneous abnormalities to severe organ dysfunction. Previous studies have shown a decrease in lymphocyte count, or lymphopenia, in SLE patients, which is often associated with disease activity. However, research on the relationship betwee…
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that involves various body systems and produces various autoantibodies. One of the autoantibodies in SLE is anti-double stranded deoxyribonucleic acid (anti-dsDNA) which is found in 70% of patients with SLE. Anti-dsDNA antibody has high specificity so it has been used as an indicator of disease activity. This study aims to dete…
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects many organs. Hospital information system data in 2016 has reported 2,166 hospitalized patients with lupus in 858 hospitals and 550 of them died. Evaluation of disease activity is essential to determine appropriate therapy and prevent complications. This study aims to analyze the association of hematological inflamma…
Backgroud: Systemic Lupus Eritematosus (SLE) is an autoimmune condition that affects multiple organs and often induced periods of remission and relapse. One of the therapies used is cyclophosphamide. However, previous studies have shown that cyclophosphamide has side effects, including lymphopenia. Methods: This studies is an analitic observational study with a cross sectional study design. Dat…
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that marked by the damage of cells and organs because of the bonding between tissues and autoantibody and immune complexes. The aim of SLE treatment is to increase survival rate and quality of patients. SLE has many clinical manifestations so it is hard to diagnose SLE patient. Mcthod: This was a descriptive observational s…