The development of information technology has driven the transformation of pharmaceutical services, one of which is the implementation of a website-based online drug sales system integrated with a management system and General Point of Sales (GPOS). This study aims to evaluate the implementation of a website-based online drug sales system using GPOS on the effectiveness of pharmaceutical servic…
Medication oversight in healthcare settings necessitates an organized and cohesive approach to enhance service effectiveness and ensure data precision. Klinik Su'adah Palembang is encountering obstacles in handling medication records due to the use of software with limited capabilities, which leads to challenges in ensuring stock accuracy, managing expired medications, and overseeing drug retur…
Memory decline is a cognitive problem that can be triggered by oxidative stress due to free radical activity. Pearl grass (Hedyotis corymbosa L.) is known to contain flavonoids and phenolic acids that have the potential to restore memory through antioxidant and neuroprotective effects. This study aimed to determine the effect of ethanol extract of pearl grass on restore memory in Swiss Webster …
Penelitian ini bertujuan untuk menguji daya analgesik dari ekstrak kulit kopi robusta (Coffea canephora) pada mencit (Mus musculus L.) galur Sub Swiss Webster. Penggunaan kulit kopi robusta, yang sering dianggap sebagai limbah, sebagai sumber potensi obat tradisional perlu diselidiki lebih lanjut. Penelitian ini menggunakan metode geliat (writhing test) yang diinduksi oleh asam asetat 1% secara…
Daun srikaya (Annona squamosa L.) mengandung flavonoid, alkaloid, saponin, dan triterpenoid yang berpotensi menimbulkan efek sedatif. Penelitian ini bertujuan mengetahui pengaruh serta dosis efektif ekstrak etanol daun srikaya terhadap efek sedatif pada mencit jantan galur Swiss Webster. Penelitian menggunakan RAL dengan 25 ekor mencit yang dibagi menjadi 5 kelompok, yaitu kontrol negatif (Twee…
Temu ireng (Curcuma aeruginosa Roxb.) is a medicinal plant from the Zingiberaceae family that is widespread in South Asia and Southeast Asia and has been reported to have antibacterial, anticancer, and antioxidant activities, especially in the rhizome. However, information on the antioxidant and antibacterial activities of fraction and isolated compounds is still limited. This study aims to ass…
ABSTRACT : Lenglengan (Leucas lavandulifolia) belongs to the Lamiaceae family. L. lavandulifolia is traditionally used in the treatment of headaches, migraines, rheumatism, and diabetes. Information on the activity and chemical content of L. lavandulifolia stems is still limited. The purpose of this study was to determine the antioxidant activity and chemical content of the most active column f…
Rambutan peel (Nephelium lappaceum L.) is an organic waste that has the potential to be used as a source of natural antioxidants due to its high phenolic and flavonoid content. This study aims to determine the total phenolic and flavonoid content, antioxidant activity, and quality characteristics of rambutan peel tea. Rambutan peel samples were dried, ground, and brewed using hot water at 90 °…
Optimization of the extraction process and testing of the antioxidant activity of Spirulina platensis microalgae extract is important for the development of natural microalgae-based antioxidant sources. Optimization was performed using multilevel factorial design 23 with 24 runs in Design Expert® 13 using three factors, namely solvent type (ethanol, acetone), temperature (25°C, 40°C), and ex…
Pelawan leaves (Tristaniopsis merguensis Griff.) are a plant that contain important secondary metabolites such as flavonoids, tannins, saponins, and phenolic compounds, which have potential roles in regulating lipid metabolism. This study aimed to evaluate the effect and effective dose of the ethanolic extract of pelawan leaves in reducing total cholesterol, Low Density Lipoprotein (LDL), and t…
Breadfruit bark (Artocarpus altilis) is a medicinal plant containing important secondary metabolites such as flavonoids, phenolics, saponins, and triterpenoids. These compounds are thought to play a role in protecting the gastric mucosa. This study aims to evaluate the antiulcer activity of ethanol extract of breadfruit bark through biochemical parameters, macroscopic, and microscopic analysis …
Drug control in hospitals is one of the important aspects of a pharmacy installation that can be analyzed from several indicators, including damaged drugs, expired drugs, and dead stock drugs. This study aims to determine the percentage value, compliance with ideal targets, and contributing factors of damaged drugs, expired drugs, and dead stock drugs using descriptive analysis at RSI Siti Khad…
Layered Double Hydroxide (LDH) is a layered material with a large surface area and good anion-exchange capacity, but its stability remains limited. To enhance its performance, LDH was modified with Muntingia calabura (MC) extract, which is rich in flavonoids and phenolics with strong antioxidant activity (IC₅₀ < 50 μg/mL). CaAl, CaCr, and CaFe LDH–MC composites were synthesized via the c…
Latar Belakang: Penggunaan obat antijamur pada anak baik topikal maupun sistemik cenderung meningkat seiring bertambahnya kasus infeksi jamur, terutama pada pasien dengan kondisi immunocompromised. Penggunaan antijamur yang tidak rasional dapat meningkatkan efek samping, resistensi, dan biaya perawatan. Data mengenai pola penggunaan antijamur pada populasi anak di Indonesia masih terbatas sehin…
Acute Respiratory Infection (ARI) is one of the most common diseases encountered among adult patients in healthcare facilities. This study aims to evaluate drug prescribing patterns and analyze their compliance with the Ministry of Health of the Republic of Indonesia's therapy guidelines for adult ARI patients at the Sukarami Public Health Center (Puskesmas) in Palembang. This study employed a …
Ethanol extract of breadfruit (Artocarpus altilis) stem bark is known to contain flavonoid compounds suspected to have potential as an antidepressant agent. This study was conducted to determine the effect and optimal concentration of the ethanol extract of breandruit stem bark for depression treatment. The test animals were divided into six groups: normal group (Na-CMC), negative group (Na-CMC…
This study aimed to determine the chemical composition and organoleptic characteristics of lozenges made from the extract of the water lettuce plant (Pistia stratiotes) through experimental laboratory methods. The experimental design used in this study was a Randomized Block Design (RBD) with 4 formulations differing in the concentration of water lettuce extract (30%, 20%, 10%, and 0%). Each fo…
Latar belakang: Aggregatibacter actinomycetemcomitans adalah bakteri gram negatif yang paling sering ditemukan pada periodontitis. Daun sirih merah sebagai bahan alami dilaporkan memiliki kandungan senyawa berupa flavonoid, alkaloid, tanin, saponin dan minyak atsiri yang terbukti memiliki efek antibakteri. Tujuan: Mengetahui ada atau tidaknya aktivitas antibakteri ekstrak daun sirih merah (Pipe…
Kidney stone disease (antinefrolithiasis) of calcium stone type is one of the health problems among Indonesian people. The use of diuretic drugs as a treatment for kidney stones can be replaced with natural ingredients to reduce the risk of side effects. Kersen leaves (Muntingia calabura L.) contain a lot of flavanes, flavones, flavanones, flavonols, and chalcones which are included in the flav…
Background: Drug allergy is a hypersensitivity reaction to medications involving immunological mechanisms that can cause clinical manifestations ranging from mild to severe, such as rash, urticaria, and anaphylaxis. Children are a vulnerable group due to their immature immune systems and limited alternative treatment options. This study aimed to determine the distribution of drug allergy incide…
Background: Wound healing is a complex biological process that progresses through the phases of inflammation, proliferation, and remodeling. Cung kediro (Solanum lycopersicum var. cerasiforme) contains lycopene, β–carotene, vitamin C, and flavonoids, which act as potent antioxidants and have the potential to accelerate epithelialization, angiogenesis, and keratinization. This study aimed to …
Introduction: Oxidative stress is an imbalance between free radicals and endogenous antioxidants that plays a role in the pathogenesis of various degenerative diseases. Natural antioxidants from plants, particularly those containing phenolic compounds and flavonoids, have become potential alternatives for the prevention of oxidative stress. Kersen mistletoe leaves contain various secondary meta…
Thrombosis is a leading global cause of cardiovascular diseases. While anticoagulants, antiplatelet agents, and thrombolytic therapies are the standard clinical treatments, iron oxide nanoparticles offer an alternative approach due to their ability to accumulate at sites of inflammation, such as thrombi and atherosclerotic plaques. These nanoparticles can act as photothermal agents, absorbing l…
Thrombosis is a condition that occurs due to an imbalance in the hemostasis system characterized by the formation of a blood clot (thrombus) in the blood vessel wall so that it can cause ischemic stroke disease. The anti-thrombotic drugs commonly used are thrombolytics. These drugs contain fibrinolytic enzymes such as protease enzymes. Pineapple (Ananas comosus (L.) Merr) is known to have an an…
Kegiatan penelitian yang dilakukan di Sungai Saka Formasi Gumai Daerah Negeri Sindang dan sekitarnya, Kecamatan Sosoh Buay Rayap, Kabupaten Ogan Komering Ulu, Provinsi Sumatera Selatan. Lokasi penelitian terbagi menjadi delapan lokasi dengan litologi batulempung karbonat dan batupasir karbonat. Penelitian ini dilakukan untuk mengidentifikasi lingkungan batimetri dan iklim purba melalui analisi…
Barringtonia acutangula or indian oak is a type of tree that are found in many swamps and river banks in Sumatera Selatan region. Determination of total phenolic content, total flavonoid content, antioxidant activity and toxicity of indian oak (Barringtonia acutangula) leaves extract was carried out. Extraction process was carried out by using increasing polarity maceration with n-hexane, ethyl…
Background: Gout is a chronic condition caused by the accumulation of monosodium urate (MSU) crystals due to hyperuricemia, often associated with a diet high in purines, obesity, and other metabolic disorders. Allopurinol is the first-line drug used to lower serum uric acid levels in gout patients. Ensuring the correct dosage of allopurinol is essential to enhance therapeutic effectiveness and …
Pengobatan yang baik berpengaruh pada tingkat pengetahuan, kepatuhan minum obat penurun kadar kolesterol dan kualitas hidup pasien. Tujuan penelitian ini adalah menganalisis hubungan antara tingkat kepatuhan minum obat dengan kualitas hidup pasien hiperkolesterolemia di Rumah Sakit Islam Siti Khadijah Palembang. Desain penelitian dilakukan secara observasional analitik dengan pendekatan cross-s…