Background: Hydatidiform mole is part of the spectrum of gestational trophoblastic disease and may progress to gestational trophoblastic tumor (GTT). This progression is thought to be associated with dysregulation of cell proliferation, cell-cycle control, and apoptosis. Molecular biomarkers such as Vitamin D Receptor (VDR), Ki-67, p21, p27, p63, and Bcl-2 are involved in oncogenic signaling pa…
Cadmium (Cd) is a highly toxic heavy metal; therefore, its presence in the environment particularly in plants or vegetables consumed by humans poses serious health risks. Several factors are suspected to contribute to cadmium contamination in Chinese cabbage (Brassica rapa subsp. pekinensis), including environmental pollution and the plant’s physiological ability to absorb heavy metals. There…
Latar Belakang: Stomatitis Aftosa Rekuren (SAR) merupakan sariawan berulang tanpa penyakit sistemik yang dapat mengganggu kualitas hidup, terutama pada mahasiswa. Salah satu faktor predisposisinya adalah pola makan yang tidak seimbang yang dapat menyebabkan defisiensi nutrisi dan menurunkan imunitas. Tujuan: “Mengetahui hubungan antara rekurensi SAR dengan jenis, jumlah, dan frekuensi pola ma…
Latar belakang: Karsinoma ovarium epitelial merupakan keganasan ginekologi dengan mortalitas tinggi dan sebagian besar terdiagnosis pada stadium lanjut. Vitamin A dan reseptor vitamin A diduga berperan dalam regulasi proliferasi dan diferensiasi sel, sedangkan CA-125 merupakan biomarker yang luas digunakan untuk menilai beban tumor dan memantau respons terapi. Namun, data mengenai hubungan kada…
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, with 150,000 new cases yearly. Roughly 40% of patients who receive rituximab in addition to vincristine, cyclophosphamide, doxorubicin, and prednisone treatment have primary refractory disease or recurrence. Although the Ann Arbor stage could determine DLBCL prognosis, new biomarkers are needed to stratify patient pro…
Background: Morbus Hansen (MH), also known as leprosy, is a chronic infectious disease caused by Mycobacterium leprae that primarily affects the skin and peripheral nerves. Despite global elimination efforts, MH remains a public health problem in Indonesia. Histopathological examination plays an essential role in establishing the diagnosis and determining the disease spectrum. This study aimed …
Preeclampsia is a pregnancy complication characterized as a multisystem syndrome marked by elevated blood pressure after 20 weeks of gestation, accompanied by proteinuria or other signs of organ dysfunction. If not properly managed, this condition may progress to eclampsia, which is characterized by seizures and poses a high risk of morbidity and even mortality for both the mother and the fetus…
Background. Cervical cancer is a malignancy of the cervical epithelium primarily caused by infection with the Human Papillomavirus (HPV). In 2022, GLOBOCAN reported 36,964 new cases and 20,708 deaths due to cervical cancer. Hematological inflammatory parameters can reflect systemic inflammation that correlates with cancer severity. This study aimed to analyze the association between hematologic…
Background: The liver is a vital organ essential for metabolism, detoxification,and nutrient storage but is highly vulnerable to damage from exposure to toxic substances like CCl4. This compound can rapidly induce liver fibrosis. Purple sweet potato (Ipomoea batatas L.), a plant widely consumed in Indonesia, is predominantly used for its tubers, while its leaves are often neglected. However, th…
Benign Prostatic Hyperplasia (BPH) is an enlargement of the prostate gland, which is commonly accompanied by the presence of inflammation known as prostatitis on histologic examination. The pattern of prostatitis can be evaluated based on the location, extent, and degree of inflammation. This study aims to provide an overview of the comprehensive evaluation of prostatitis and the clinical profi…
Kanker ovarium, khususnya subtipe serous, merupakan penyebab kematian utama kanker ginekologi pada perempuan. Keterlambatan diagnosis dan pengobatan yang kurang efektif merupakan salah satu penyebab tingginya angka kejadian dan mortalitas. Faktor risiko yang dapat dimodifikasi seperti indeks massa tubuh (IMT) dan paritas diyakini memiliki potensi pencegahan terhadap karsinoma ovarium subtipe se…
Elderly individuals are a vulnerable group in need of support to improve their quality of life. The Kartini Elderly School in 15 Ulu Subdistrict, Jakabaring District, Palembang City serves as a community-based empowerment initiative for the elderly. This study aims to describe the process and impact of empowerment experienced by participants in the elderly school. The research used a qualitativ…
This study aims to describe educational practices in rural schools in Muara Telang Subdistrict, Banyuasin Regency, using Pierre Bourdieu's theory of arena, habitus, and capital. This study uses a qualitative approach with a descriptive method. The results of the study indicate that educational practices in rural areas occur within a unique social context, influenced by difficult geographical co…
Pathological vaginal discharge is a condition in which the fluid discharged from the vagina undergoes changes in colour, odour, texture, or volume. Approximately 75% of women worldwide have experienced vaginal discharge at least once in their lifetime. Previous research suggests that knowledge, attitude, personal hygiene behaviour, stress, and physical activity may be risk factors for pathologi…
Background: Colitis is an inflammatory condition that occurs in the mucosa or submucosa of the colon and can be acute or chronic. The initial survey results of the study found many patients suffering from colitis such as ulcerative colitis, Crohn's Disease, and radiation colitis at the Pathology Anatomy Laboratory of Dr. Moh. Hoesin Palembang Hospital, so this study helps to summarize colitis d…