Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, with 150,000 new cases yearly. Roughly 40% of patients who receive rituximab in addition to vincristine, cyclophosphamide, doxorubicin, and prednisone treatment have primary refractory disease or recurrence. Although the Ann Arbor stage could determine DLBCL prognosis, new biomarkers are needed to stratify patient pro…
Background Nasopharyngeal carcinoma (NPC) is a malignant tumor that tends to be diagnosed at cm advanced stage, so they have low survival rate and poor prognosis. Cyclooxygenase-2 is an enzyme that is induced during injlammation and neoplastic and expressed in various tumors. The aim of this study is to evaluate the expression of cyclooxygenase-2 in nasopharyngeal carcinoma and to assess the co…
Background. The mosi common breast carcinomas are ductal (40-70%) and lobular (5-15%) types. They have distinct histopathologycal features, but the challenge for the pathologists are sometimes boih features can appears on the same tumor in confusing pattern. Jn order to help distinguishing this two types carcinomas, there are many researchs for E-cadherin expression and proven as usefitl tools.…
Background. Triple negative breast cancer (TNBC) is defined as a subtype that is negative for estrogen receptor, progesterone receptor and HER-2,accounts for 10-70% ofall breast cancer.TNBC have aggressive behavior, poor prognosis, unique clinicohistopathologic characteristic and molecular profiles. This study designedto identified characteristics andfactors are had relationship with TNBC subty…