Background: Solid tumors are a major cause of morbidity and mortality in children. The outcomes of pediatric patients with solid tumors are influenced by various factors, including demographic characteristics, nutritional status, perinatal history, socioeconomic conditions, tumor stage, and the type of therapy administered. Data regarding outcomes and associated factors among children with soli…
Meningioma is the most commonly diagnosed primary tumor of the central nervous system, with the majority being benign (WHO Grade I). Imaging modalities such as CT-Scan and MRI play a crucial role in the diagnosis and evaluation of meningioma. This study aims to describe the imaging features of brain scans in meningioma patients at Dr. Mohammad Hoesin General Hospital Palembang during the period…
Liver tumor is a condition where there is abnormal cells that grow in the liver and causes the important role of the liver organ to be distrupted. The process of separating abnormal cells and healthy tissue in liver tumors can be done by image segmentation using Convolutional Neural Network (CNN). This study proposes liver tumor segmentation on CT-scan data using a combination of DeepLabV3+, Ef…
Sedentary lifestyle yang ditandai dengan kurangnya aktivitas fisik, serta pola konsumsi makanan yang tidak sehat, diduga dapat meningkatkan risiko terkena kanker payudara. Kanker payudara merupakan salah satu jenis kanker yang paling umum terjadi pada wanita, termasuk remaja putri. Tingkat kewaspadaan dan pemahaman mengenai faktor risiko kanker payudara sangat penting dalam upaya pencegahan din…
ABSTRAK PREVALENSI DAN FAKTOR YANG MEMENGARUHI LUARAN TUMOR PADAT PADA ANAK DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE 2016-2020 (Muhammad Luthfi Hadhyan, 22 Desember 2023, 117 halaman) Fakultas Kedokteran Universitas Sriwijaya Latar Belakang. Tumor padat adalah benjolan yang muncul pada tubuh dan disebabkan oleh keganasan atau kanker. Beberapa jenis tumor padat yang paling umum terjadi pada…
Background: Over the last 10 years, Tumor infiltrating lymphocytes (TILs) have played an important role in predicting patient prognosis in several types of cancer, including ovarian cancer. TILs play a significant role in the Tumor Microenvironment (TME) and can influence prognosis. Associations between clinico-histopathological characteristics and TIL density have been observed in other cancer…
Background. Ovarian cancer is the seventh leading cause of cancer and the eighth most common cause of cancer death in women worldwide. Epithelial ovarian cancer is one of the second-leading causes of death from gynecologic cancer. 90% of ovarian cancer cases originate from epithelial cells. Some risk factors that increase the occurrence of ovarian cancer include age, body mass index, family his…
Ovarian neoplasms are one of the most common causes of female patients being referred to obstetrics departments. The incidence and characteristics of benign ovarian neoplasms tend to vary in each population. This study aims to determine the prevalence and distribution of characteristics of patients with benign ovarian neoplasms at Dr. Mohammad Hoesin Palembang Hospital. This study is a descript…
Background: Breast cancer holds the highest number of cases between incidences of cancer in Indonesia. Developing countries have a higher rate of mortality in comparison to developed countries due to late diagnosis and its worsening prognosis. Laboratory values have a high potential as one of the methods of early detection of breast cancer. Several studies reveal results of laboratory evaluatio…
Introduction: Glial tumors are tumors that originate from glial cells of the central nervous system. These tumors are aggressive and it is one of the leading causes of death from cancer. The purpose of this study was to determine the clinicopathological characteristics of glial tumor patients at RSUP Dr. Mohammad Hoesin Palembang in 2019-2022. Method: This study is a descriptive study. Samples …
Background: New cases of skin malignancy have been increasing every year for the past decade. The latest data regarding new cases of skin cancers are needed as the first step in preventing and reducing the number of new skin cancer cases. the purpose of this research was to determine the incidence and characteristics of skin cancer patients at RSUP Dr. Mohammad Hoesin Palembang for the 2019 –…
Kanker merupakan kondisi terjadinya pertumbuhan jaringan yang tidak normal dan tidak terkendali yang dapat menyebabkan kerusakan fungsi tubuh dan berdampak negatif pada kesehatan. Kanker dapat dialami oleh orang dewasa maupun anak-anak. Salah satu jenis kanker yang dialami anak adalah leukemia jenis akut. Leukemia pada anak umumnya sulit dideteksi karena kurangnya informasi dan pengetahuan oran…
Childhood cancer is increasing every year, especially in low- and middle-income countries. The treatment of cancer in children must be carried out continuously and for a long time, so the role of parents in supporting the treatment of children with cancer is very important. Parents' self-efficacy plays an important role in accompanying children through the process of treating children with canc…
The patient's ability to do self-care will increase the treatment process during the treatment stages of pulmonary TB. The family has a very important role in caring for family members who suffer from pulmonary TB. The role of family support will influence the patient's decision to complete treatment or not. Families of pulmonary TB patients must have good knowledge so they can provide good sup…
Invasive breast carcinoma of no special type (ICNST) merupakan jenis karsinoma payudara invasif yang paling banyak terdiagnosis. Human Epidermal Growth Factor Receptor 2 (HER2) dapat menstimulasi transkripsi inti sel secara abnormal sehingga menyebabkan karsinogenesis pada jaringan payudara. Penelitian ini bertujuan untuk mengetahui hubungan antara ekspresi HER2 terhadap klinikopatologi ICNST. …
Background. Brain tumor is defined as the uncontrolled proliferation of brain cells. Brain tumor can be classified as primary/secondary and can be categorized as benign/malignant regarding to its severity. The development of brain tumor can be induced by several factors, such as the long-term usage of hormonal contraceptives. A study has proven that there is approximately twelvefold increase in…
Tumor mesenkimal uterus adalah sekelompok neoplasma yang heterogen, terdiri dari beberapa jenis tumor yang dibedakan berdasarkan morfologi molekuler. Kasus tumor mesenkimal uterus terus mengalami peningkatan dalam beberapa tahun terakhir. Namun, data kejadian tumor ini masih sulit untuk didapatkan. Sehingga, diperlukan penelitian untuk menggambarkan distribusi frekuensi dan karakteristik klinis…
Background: Head and neck tumors can involve both soft tissue and hard tissue with a global incidence of 600,000 cases per year and men are more at risk than women. Low public awareness and limited access to health facilities can be a factor for patients arriving at Type A Hospitals with advanced or large-sized tumors that require wide excision and cause large defects that interfere with functi…
Background : In Indonesia, cervical cancer is 36,633 cases or equal to 9.2% caused by infection with the Human Papilloma Virus (HPV) which is the main cause of cervical cancer. One of the problems that often arise in patients with cervical cancer is pain. Pain in cancer patients is chronic pain caused by the course of cervical cancer. One of the treatments for cervical cancer patients who exper…
Ovarian cancer is the sixth most common disease and the eighth leading cause of death in Indonesia. The types of ovarian cancer are divided into 5: epithelial, germ cell, sex cord-stromal, other cancers, and metastases. Thus, this study aims to describe the incidence, clinical characteristics, and histopathological characteristics of ovarian cancer at RSUP Dr. Mohammad Hoesin Palembang from Jan…
Introduction: 2021, 59 Pages) Malignant ovarian tumor is one of the most common malignancies in women and has high mortality rate. Globocan report in 2018 showed the worldwide incidence of malignant ovarian tumor is 5.7 per 100,000 with mortality rate of 4 per 100,000. One contributing factor for the high mortality rate is inadequate early detection methods caused by high hetero geneity of immu…
Latar Belakang: Mioma uteri atau leiomyoma uteri adalah tumor jinak sel otot polos miometrium yang dikelilingi oleh pseudocapsule. Mioma uteri terjadi pada wanita usia reproduktif dan akan perlahan menghilang saat menopause. Mioma uteri merupakan masalah reproduksi terbanyak kedua yang diderita oleh wanita di Indonesia setelah kanker serviks. Angka kejadian mioma uteri di dunia sebesar 20-35% s…
Background: Malignant melanoma in skin tumors originate from melanocyte cells. The development of melanoma depends greatly on the interaction of melanoma cancer cells with microenvirontment tumor (TME). Tumor Associated Macrophages (TAMs) are drawn to tumor cells due to the release of chemokine by tumor cells. A high density of TAMs towards tumors corelate with poor prognosis. The purpose of th…
A tumor is an abnormal growth of body tissue in the body, it can be benign or malignant. According to data from the Department of Pulmonology and Respiratory Medicine, FKUI-Persahabatan Hospital, in the last 10 years there has been an increase in the incidence of lung tumors. At this time, it is still rare to find data that discusses the characteristics of tumor patients undergoing surgery, esp…
Nasopharyngeal carcinoma is a type of epithelial carcinoma originating from the mucosal lining of the nasopharynx. Nasopharyngeal carcinoma is the most common malignant tumor of the head and neck in Indonesia and occupies aranked 5th malignant tumor of the human body based on its incidence and mortality rate in Indonesia. The purpose of this study was to determine the relationship of risk facto…
Latar belakang. Meningioma adalah salah satu jenis tumor otak yang paling sering ditemui. Penelitian ini bertujuan untuk memberikan gambaran tentang karakteristik pasien Meningioma di RSUP Dr. Mohammad Hoesin Palembang. Metode. Penelitian ini menggunakan jenis penelitian observasional deskriptif dengan desain penelitian cross sectional. Hasil. Meningioma paling banyak didiagnosis pada kelompok …
Angiogenesis is the process of new blood vessel growth that has an important role in tumor development. One method to assess angiogenesis is to measure microvessel density (MVD). A high MVD is associated with a poor prognosis in various types of cancer. The aim of this study was to determine the association between microvessel density and clinicohistopathological characteristics in patients wit…
Ovarian cancer in one of the most common cancers. Neutrophils as one of the immune cells turns out play an important role in both development dan inhibiton of tumor based on their phenotype. This study aims to compare the Tumor- Associated Neutrophils (TAN) in the tumor microenvironment based on the clinical and histopathological characteristics of ovarian cancer pastients at the Anatomical Pat…
Ovarian malignant tumours is a gynecological malignancy with the highest mortality. Immunotherapy, being the main treatment modality, has shown poor efficacy due to the heterogenity of TILs in TME. It is important for us to identify the distribution and density of TILs in TME based on clinicohistopathological characteristics. This type of research is analytic observational with aapproach cross…
Background: Colorectal adenocarcinoma is a malignant tumor in the epithelium of the colon with glandular or mucinus differentiation. Colorectal cancer is one of the leading causes of death worldwide, accounting for 9,2% of the death. Tumor-Associated Neutrophils (TANs), which are the components of the tumor microenvironment, are known to be prognostic determinants in colorectal cancer patients.…